Author results

2DUV
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STRUCTURE OF CDK2 WITH A 3-HYDROXYCHROMONES
Descriptor:Cell division protein kinase 2, 2-(3,4-DIHYDROXYPHENYL)-8-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-3-HYDROXY-6-METHYL-4H-CHROMEN-4-ONE
Authors:Kim, K.H., Lee, J., Park, T., Jeong, S., Hong, C.
Deposit date:2006-07-27
Release date:2007-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:3-Hydroxychromones as cyclin-dependent kinase inhibitors: synthesis and biological evaluation.
Bioorg.Med.Chem.Lett., 17, 2007
5JUY
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ACTIVE HUMAN APOPTOSOME WITH PROCASPASE-9
Descriptor:Apoptotic protease-activating factor 1, Cytochrome c, Caspase-9, ...
Authors:Cheng, T.C., Hong, C., Akey, I.V., Yuan, S., Akey, C.W.
Deposit date:2016-05-10
Release date:2016-10-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:A near atomic structure of the active human apoptosome.
Elife, 5, 2016
5TCP
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NEAR-ATOMIC RESOLUTION CRYO-EM STRUCTURE OF THE PERIPLASMIC DOMAINS OF PRGH AND PRGK
Descriptor:Lipoprotein PrgK, Protein PrgH
Authors:Worrall, L.J., Hong, C., Vuckovic, M., Bergeron, J.R.C., Huang, R.K., Yu, Z., Strynadka, N.C.J.
Deposit date:2016-09-15
Release date:2016-12-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body.
Nature, 540, 2016
5TCQ
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NEAR-ATOMIC RESOLUTION CRYO-EM STRUCTURE OF THE SALMONELLA SPI-1 TYPE III SECRETION INJECTISOME SECRETIN INVG
Descriptor:Protein InvG
Authors:Worrall, L.J., Hong, C., Vuckovic, M., Bergeron, J.R.C., Huang, R.K., Yu, Z., Strynadka, N.C.J.
Deposit date:2016-09-15
Release date:2016-12-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body.
Nature, 540, 2016
5TCR
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ATOMIC MODEL OF THE SALMONELLA SPI-1 TYPE III SECRETION INJECTISOME BASAL BODY PROTEINS INVG, PRGH, AND PRGK
Descriptor:Protein InvG, Lipoprotein PrgK, Protein PrgH
Authors:Worrall, L.J., Hong, C., Vuckovic, M., Bergeron, J.R.C., Huang, R.K., Yu, Z., Strynadka, N.C.J.
Deposit date:2016-09-15
Release date:2016-12-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body.
Nature, 540, 2016
5WC3
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SPOIIIAG
Descriptor:SpoIIIAG, Stage III sporulation engulfment assemblyprotein
Authors:Zeytuni, N., Hong, C., Worrall, L.J., Huang, R.K., Yu, Z., Strynadka, N.C.J.
Deposit date:2017-06-29
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Near-atomic resolution cryoelectron microscopy structure of the 30-fold homooligomeric SpoIIIAG channel essential to spore formation in Bacillus subtilis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6B6H
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THE CRYO-EM STRUCTURE OF A BACTERIAL CLASS I TRANSCRIPTION ACTIVATION COMPLEX
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Liu, B., Hong, C., Huang, R., Yu, Z., Steitz, T.A.
Deposit date:2017-10-02
Release date:2017-11-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of bacterial transcription activation.
Science, 358, 2017
6D03
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CRYO-EM STRUCTURE OF A PLASMODIUM VIVAX INVASION COMPLEX ESSENTIAL FOR ENTRY INTO HUMAN RETICULOCYTES; ONE MOLECULE OF PARASITE LIGAND.
Descriptor:Transferrin receptor protein 1, Serotransferrin, Reticulocyte binding protein 2, ...
Authors:Gruszczyk, J., Huang, R.K., Hong, C., Yu, Z., Tham, W.H.
Deposit date:2018-04-10
Release date:2018-06-20
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6D04
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CRYO-EM STRUCTURE OF A PLASMODIUM VIVAX INVASION COMPLEX ESSENTIAL FOR ENTRY INTO HUMAN RETICULOCYTES; TWO MOLECULES OF PARASITE LIGAND, SUBCLASS 1.
Descriptor:Transferrin receptor protein 1, Serotransferrin, Reticulocyte binding protein 2, ...
Authors:Gruszczyk, J., Huang, R.K., Hong, C., Yu, Z., Tham, W.H.
Deposit date:2018-04-10
Release date:2018-06-20
Last modified:2018-07-11
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6D05
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CRYO-EM STRUCTURE OF A PLASMODIUM VIVAX INVASION COMPLEX ESSENTIAL FOR ENTRY INTO HUMAN RETICULOCYTES; TWO MOLECULES OF PARASITE LIGAND, SUBCLASS 2.
Descriptor:Transferrin receptor protein 1, Serotransferrin, Reticulocyte binding protein 2, ...
Authors:Gruszczyk, J., Huang, R.K., Hong, C., Yu, Z., Tham, W.H.
Deposit date:2018-04-10
Release date:2018-06-20
Last modified:2018-07-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6DWB
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STRUCTURE OF THE SALMONELLA SPI-1 TYPE III SECRETION INJECTISOME NEEDLE FILAMENT
Descriptor:Protein PrgI
Authors:Hu, J., Hong, C., Worrall, L.J., Vuckovic, M., Yu, Z., Strynadka, N.C.J.
Deposit date:2018-06-26
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6NJO
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STRUCTURE OF THE ASSEMBLED ATPASE ESCN FROM THE ENTEROPATHOGENIC E. COLI (EPEC) TYPE III SECRETION SYSTEM
Descriptor:Translocator EscN, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Majewski, D.D., Worrall, L.J., Hong, C., Atkinson, C.E., Vuckovic, M., Watanabe, N., Yu, Z., Strynadka, N.C.J.
Deposit date:2019-01-03
Release date:2019-02-20
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry.
Nat Commun, 10, 2019
6NJP
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STRUCTURE OF THE ASSEMBLED ATPASE ESCN IN COMPLEX WITH ITS CENTRAL STALK ESCO FROM THE ENTEROPATHOGENIC E. COLI (EPEC) TYPE III SECRETION SYSTEM
Descriptor:Translocator EscN, EscO, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Majewski, D.D., Worrall, L.J., Hong, C., Atkinson, C.E., Vuckovic, M., Watanabe, N., Yu, Z., Strynadka, N.C.J.
Deposit date:2019-01-03
Release date:2019-02-20
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry.
Nat Commun, 10, 2019
6GQF
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THE STRUCTURE OF MOUSE ASTERA (GRAMD1A) WITH 25-HYDROXY CHOLESTEROL
Descriptor:GRAM domain-containing protein 1A, 25-HYDROXYCHOLESTEROL, GLYCEROL
Authors:Fairall, L., Gurnett, J.E., Vashi, D., Sandhu, J., Tontonoz, P., Schwabe, J.W.R.
Deposit date:2018-06-07
Release date:2018-09-26
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells.
Cell, 175, 2018
1IYM
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RING-H2 FINGER DOMAIN OF EL5
Descriptor:EL5, ZINC ION
Authors:Katoh, E., Katoh, S., Minami, E., Yamazaki, T.
Deposit date:2002-08-30
Release date:2003-07-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:High Precision NMR Structure and Function of the RING-H2 Finger Domain of EL5, a Rice Protein Whose Expression Is Increased upon Exposure to Pathogen-derived Oligosaccharides
J.Biol.Chem., 278, 2003
2YHN
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THE IDOL-UBE2D COMPLEX MEDIATES STEROL-DEPENDENT DEGRADATION OF THE LDL RECEPTOR
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE MYLIP, ZINC ION
Authors:Fairall, L., Goult, B.T., Millard, C.J., Tontonoz, P., Schwabe, J.W.R.
Deposit date:2011-05-04
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
2YHO
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THE IDOL-UBE2D COMPLEX MEDIATES STEROL-DEPENDENT DEGRADATION OF THE LDL RECEPTOR
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE MYLIP, UBIQUITIN-CONJUGATING ENZYME E2 D1, ZINC ION, ...
Authors:Fairall, L., Goult, B.T., Millard, C.J., Tontonoz, P., Schwabe, J.W.R.
Deposit date:2011-05-04
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
6BPA
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PLASMODIUM VIVAX RETICULOCYTE BINDING PROTEIN 2B (PVRBP2B) BOUND TO MONOCLONAL ANTIBODY 3E9
Descriptor:Reticulocyte binding protein 2, putative, Monoclonal antibody 3E9 Fab heavy chain, ...
Authors:Gruszczyk, J., Chan, L.J., Tham, W.H.
Deposit date:2017-11-22
Release date:2018-06-20
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPB
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PLASMODIUM VIVAX INVASION BLOCKING MONOCLONAL ANTIBODY 4F7
Descriptor:Monoclonal antibody 4F7 Fab heavy chain, Monoclonal antibody 4F7 Fab light chain
Authors:Gruszczyk, J., Chan, L.J., Tham, W.H.
Deposit date:2017-11-22
Release date:2018-06-20
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPC
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PLASMODIUM VIVAX RETICULOCYTE BINDING PROTEIN 2B (PVRBP2B) BOUND TO MONOCLONAL ANTIBODY 4F7
Descriptor:Reticulocyte binding protein 2, putative, Monoclonal antibody 4F7 Fab heavy chain, ...
Authors:Gruszczyk, J., Chan, L.J., Tham, W.H.
Deposit date:2017-11-22
Release date:2018-06-20
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPD
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PLASMODIUM VIVAX INVASION BLOCKING MONOCLONAL ANTIBODY 10B12
Descriptor:Monoclonal antibody 10B12 Fab heavy chain, Monoclonal antibody 10B12 Fab light chain
Authors:Gruszczyk, J., Chan, L.J., Tham, W.H.
Deposit date:2017-11-22
Release date:2018-06-20
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPE
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PLASMODIUM VIVAX RETICULOCYTE BINDING PROTEIN 2B (PVRBP2B) BOUND TO MONOCLONAL ANTIBODY 6H1
Descriptor:Reticulocyte binding protein 2, putative, Monoclonal antibody 6H1 Fab heavy chain, ...
Authors:Gruszczyk, J., Chan, L.J., Tham, W.H.
Deposit date:2017-11-22
Release date:2018-06-20
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6CES
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CRYO-EM STRUCTURE OF GATOR1-RAG
Descriptor:GATOR complex protein NPRL2, GATOR complex protein NPRL3, GATOR complex protein DEPDC5, ...
Authors:Shen, K., Huang, R.K., Brignole, E.J., Yu, Z., Sabatini, D.M.
Deposit date:2018-02-12
Release date:2018-03-28
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.
Nature, 556, 2018
6CET
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CRYO-EM STRUCTURE OF GATOR1
Descriptor:GATOR complex protein NPRL2, GATOR complex protein NPRL3, GATOR complex protein DEPDC5
Authors:Shen, K., Huang, R.K., Brignole, E.J., Yu, Z., Sabatini, D.M.
Deposit date:2018-02-12
Release date:2018-03-28
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.
Nature, 556, 2018
6DUZ
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STRUCTURE OF THE PERIPLASMIC DOMAINS OF PRGH AND PRGK FROM THE ASSEMBLED SALMONELLA TYPE III SECRETION INJECTISOME NEEDLE COMPLEX
Descriptor:Protein PrgH, Lipoprotein PrgK
Authors:Hu, J., Worrall, L.J., Vuckovic, M., Atkinson, C.E., Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
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