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6IF6
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BU of 6if6 by Molmil
Structure of the periplasmic domain of SflA
Descriptor: GLYCEROL, PHOSPHATE ION, Protein SflA
Authors:Nishikawa, S, Sakuma, M, Kojima, S, Homma, M, Imada, K.
Deposit date:2018-09-18
Release date:2019-05-01
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the periplasmic domain of SflA involved in spatial regulation of the flagellar biogenesis of Vibrio reveals a TPR/SLR-like fold.
J.Biochem., 166, 2019
2D4U
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BU of 2d4u by Molmil
Crystal Structure of the ligand binding domain of the bacterial serine chemoreceptor Tsr
Descriptor: Methyl-accepting chemotaxis protein I
Authors:Imada, K, Tajima, H, Namba, K, Sakuma, M, Homma, M, Kawagishi, I.
Deposit date:2005-10-24
Release date:2006-11-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Ligand specificity determined by differentially arranged common ligand-binding residues in the bacterial amino acid chemoreceptors Tsr and Tar.
J.Biol.Chem., 2011
7CIK
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BU of 7cik by Molmil
Structure of the 58-213 fragment of FliF
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, Flagellar M-ring protein
Authors:Takekawa, T, Sakuma, M, Kojima, S, Homma, M, Imada, K.
Deposit date:2020-07-07
Release date:2021-02-17
Last modified:2021-09-01
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Two Distinct Conformations in 34 FliF Subunits Generate Three Different Symmetries within the Flagellar MS-Ring.
Mbio, 12, 2021
5Y3Z
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BU of 5y3z by Molmil
Structure of the periplasmic domain of the MotB L119P mutant from Salmonella (crystal form 1)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ARGININE, IMIDAZOLE, ...
Authors:Takao, M, Kojima, S, Sakuma, M, Homma, M, Imada, K.
Deposit date:2017-07-31
Release date:2018-04-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Helix Rearrangement in the Periplasmic Domain of the Flagellar Stator B Subunit Activates Peptidoglycan Binding and Ion Influx.
Structure, 26, 2018
5Y40
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BU of 5y40 by Molmil
Structure of the periplasmic domain of the MotB L119P mutant from Salmonella (crystal form 2)
Descriptor: Motility protein B
Authors:Takao, M, Kojima, S, Sakuma, M, Homma, M, Imada, K.
Deposit date:2017-07-31
Release date:2018-04-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Helix Rearrangement in the Periplasmic Domain of the Flagellar Stator B Subunit Activates Peptidoglycan Binding and Ion Influx.
Structure, 26, 2018
6AHP
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BU of 6ahp by Molmil
Structure of the 58-167 fragment of FliL
Descriptor: Flagellar protein FliL
Authors:Takekawa, N, Isumi, M, Sakuma, M, Kojima, S, Homma, M, Imada, K.
Deposit date:2018-08-20
Release date:2019-03-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure ofVibrioFliL, a New Stomatin-like Protein That Assists the Bacterial Flagellar Motor Function.
MBio, 10, 2019
6AHQ
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BU of 6ahq by Molmil
Structure of the 40-167 fragment of FliL
Descriptor: Flagellar protein FliL
Authors:Takekawa, N, Isumi, M, Sakuma, M, Kojima, S, Homma, M, Imada, K.
Deposit date:2018-08-20
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.398 Å)
Cite:Structure ofVibrioFliL, a New Stomatin-like Protein That Assists the Bacterial Flagellar Motor Function.
MBio, 10, 2019
2ZVY
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BU of 2zvy by Molmil
Structure of the periplasmic domain of MotB from Salmonella (crystal form II)
Descriptor: Chemotaxis protein motB
Authors:Kojima, S, Homma, M, Namba, K, Imada, K.
Deposit date:2008-11-26
Release date:2009-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Stator assembly and activation mechanism of the flagellar motor by the periplasmic region of MotB
Mol.Microbiol., 73, 2009
2ZF8
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BU of 2zf8 by Molmil
Crystal structure of MotY
Descriptor: Component of sodium-driven polar flagellar motor
Authors:Imada, K, Kojima, S, Namba, K, Homma, M.
Deposit date:2007-12-25
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Insights into the stator assembly of the Vibrio flagellar motor from the crystal structure of MotY
Proc.Natl.Acad.Sci.Usa, 105, 2008
2ZOV
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BU of 2zov by Molmil
Structure of the periplasmic domain of MotB from Salmonella (crystal form I)
Descriptor: Chemotaxis protein motB
Authors:Imada, K, Kojima, S, Namba, K, Homma, M.
Deposit date:2008-06-09
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Stator assembly and activation mechanism of the flagellar motor by the periplasmic region of MotB
Mol.Microbiol., 73, 2009
7DM9
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BU of 7dm9 by Molmil
Crystal structure of FliM middle domain (51-229) from Vibro alginolyticus
Descriptor: Flagellar motor switch protein FliM
Authors:Takekawa, N, Homma, M, Imada, K.
Deposit date:2020-12-02
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:A slight bending of an alpha-helix in FliM creates a counterclockwise-locked structure of the flagellar motor in Vibrio.
J.Biochem., 170, 2021
7DMA
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BU of 7dma by Molmil
Crystal structure of FliM middle domain (46-231) with R49P substitution from Vibro alginolyticus
Descriptor: Flagellar motor switch protein FliM
Authors:Takekawa, N, Homma, M, Imada, K.
Deposit date:2020-12-03
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:A slight bending of an alpha-helix in FliM creates a counterclockwise-locked structure of the flagellar motor in Vibrio.
J.Biochem., 170, 2021
3W1E
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BU of 3w1e by Molmil
Structure of FlgT, a flagellar basal body component protein
Descriptor: Flagella basal-body protein
Authors:Terashima, H, Sakuma, M, Homma, M, Imada, K.
Deposit date:2012-11-14
Release date:2013-04-03
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insight into the assembly mechanism in the supramolecular rings of the sodium-driven Vibrio flagellar motor from the structure of FlgT
Proc.Natl.Acad.Sci.USA, 110, 2013
3WPW
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BU of 3wpw by Molmil
Structure of PomBc5, a periplasmic fragment of PomB from Vibrio
Descriptor: ACETATE ION, PomB
Authors:Takao, M, Sakuma, M, Zhu, S, Homma, M, Kojima, S, Imada, K.
Deposit date:2014-01-17
Release date:2014-09-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational change in the periplasmic region of the flagellar stator coupled with the assembly around the rotor
Proc. Natl. Acad. Sci. U.S.A., 111, 2014
3WPX
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BU of 3wpx by Molmil
Structure of PomBc4, a periplasmic fragment of PomB from Vibrio alginolyticus
Descriptor: PomB
Authors:Takao, M, Sakuma, M, Zhu, S, Homma, M, Kojima, S, Imada, K.
Deposit date:2014-01-17
Release date:2014-09-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational change in the periplasmic region of the flagellar stator coupled with the assembly around the rotor
Proc. Natl. Acad. Sci. U.S.A., 111, 2014
3W0E
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BU of 3w0e by Molmil
Structure of elastase inhibitor AFUEI (crystal form II)
Descriptor: Elastase inhibitor AFUEI
Authors:Imada, K, Sakuma, M, Okumura, Y, Ogawa, K, Nikai, T, Homma, M.
Deposit date:2012-10-29
Release date:2013-05-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray Structure Analysis and Characterization of AFUEI, an Elastase Inhibitor from Aspergillus fumigatus
J.Biol.Chem., 288, 2013
3W0D
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BU of 3w0d by Molmil
Structure of elastase inhibitor AFUEI (cyrstal form I)
Descriptor: Elastase inhibitor AFUEI
Authors:Imada, K, Sakuma, M, Okumura, Y, Ogawa, K, Nikai, T, Homma, M.
Deposit date:2012-10-29
Release date:2013-05-15
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray Structure Analysis and Characterization of AFUEI, an Elastase Inhibitor from Aspergillus fumigatus
J.Biol.Chem., 288, 2013
8GQY
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BU of 8gqy by Molmil
CryoEM structure of pentameric MotA from Aquifex aeolicus
Descriptor: Motility protein A
Authors:Nishikino, T, Takekawa, N, Kishikawa, J, Hirose, M, Onoe, S, Kato, T, Imada, K.
Deposit date:2022-08-31
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of MotA, a flagellar stator protein, from hyperthermophile.
Biochem.Biophys.Res.Commun., 631, 2022
3ATP
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BU of 3atp by Molmil
Structure of the ligand binding domain of the bacterial serine chemoreceptor Tsr with ligand
Descriptor: Methyl-accepting chemotaxis protein I, SERINE
Authors:Tajima, H, Sakuma, M, Homma, K, Kawagishi, I, Imada, K.
Deposit date:2011-01-07
Release date:2011-10-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ligand specificity determined by differentially arranged common ligand-binding residues in bacterial amino acid chemoreceptors Tsr and Tar.
J.Biol.Chem., 286, 2011
2ZVZ
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BU of 2zvz by Molmil
Structure of the periplasmic domain of MotB from Salmonella (crystal form III)
Descriptor: Chemotaxis protein motB
Authors:Imada, K, Kojima, S, Namba, K, Homma, S.
Deposit date:2008-11-26
Release date:2009-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Stator assembly and activation mechanism of the flagellar motor by the periplasmic region of MotB
Mol.Microbiol., 73, 2009
6P5P
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BU of 6p5p by Molmil
Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Anti-Tumor Agent
Descriptor: 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one, Rho-associated protein kinase 2
Authors:Hoffman, I.D, Skene, R.J.
Deposit date:2019-05-30
Release date:2020-01-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent.
J.Med.Chem., 63, 2020
6P5M
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BU of 6p5m by Molmil
Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Anti-Tumor Agent
Descriptor: 6-(5-methyl-1H-pyrazol-4-yl)-2-[(pyrrolidin-1-yl)methyl]thieno[3,2-d]pyrimidin-4(3H)-one, Rho-associated protein kinase 2
Authors:Hoffman, I.D, Skene, R.J.
Deposit date:2019-05-30
Release date:2020-01-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent.
J.Med.Chem., 63, 2020
5AVE
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BU of 5ave by Molmil
The ligand binding domain of Mlp37 with serine
Descriptor: Methyl-accepting chemotaxis (MCP) signaling domain protein, SERINE
Authors:Takahashi, Y, Sumita, K, Uchida, Y, Nishiyama, S, Kawagishi, I, Imada, K.
Deposit date:2015-06-15
Release date:2016-03-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of a Vibrio cholerae chemoreceptor that senses taurine and amino acids as attractants
Sci Rep, 6, 2016
5U7Q
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BU of 5u7q by Molmil
Identification of A New Class of Potent Cdc7 Inhibitors Designed by Putative Pharmacophore Model: Synthesis and Biological Evaluation of 2,3-Dihydrothieno[3,2-d]pyrimidin-4(1H)-ones
Descriptor: Rho-associated protein kinase 2
Authors:Hoffman, I.D.
Deposit date:2016-12-12
Release date:2017-03-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones.
Bioorg. Med. Chem., 25, 2017
5U7R
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BU of 5u7r by Molmil
Identification of A New Class of Potent Cdc7 Inhibitors Designed by Putative Pharmacophore Model: Synthesis and Biological Evaluation of 2,3-Dihydrothieno[3,2-d]pyrimidin-4(1H)-ones
Descriptor: (1s,4s)-4-(4-fluorophenyl)-4-hydroxy-6'-(5-methyl-1H-pyrazol-4-yl)-1'H-spiro[cyclohexane-1,2'-thieno[3,2-d]pyrimidin]-4'(3'H)-one, Rho-associated protein kinase 2
Authors:Hoffman, I.D, Skene, R.J.
Deposit date:2016-12-12
Release date:2017-03-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones.
Bioorg. Med. Chem., 25, 2017

 

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