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1BVK
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BU of 1bvk by Molmil
HUMANIZED ANTI-LYSOZYME FV COMPLEXED WITH LYSOZYME
Descriptor: HULYS11, LYSOZYME
Authors:Holmes, M.A, Buss, T.N, Foote, J.
Deposit date:1998-09-16
Release date:1999-02-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational correction mechanisms aiding antigen recognition by a humanized antibody.
J.Exp.Med., 187, 1998
1BVL
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BU of 1bvl by Molmil
HUMANIZED ANTI-LYSOZYME FV
Descriptor: HULYS11
Authors:Holmes, M.A, Foote, J.
Deposit date:1998-09-16
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural consequences of humanizing an antibody.
J.Immunol., 158, 1997
1ZSO
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BU of 1zso by Molmil
Hypothetical protein from plasmodium falciparum
Descriptor: hypothetical protein
Authors:Holmes, M.A, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-05-24
Release date:2005-06-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.
Acta Crystallogr.,Sect.F, 62, 2006
2A03
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BU of 2a03 by Molmil
Superoxide dismutase protein from plasmodium berghei
Descriptor: Fe-superoxide dismutase homolog, MANGANESE (II) ION, ZINC ION
Authors:Holmes, M.A, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-06-15
Release date:2005-06-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Hypothetical protein from plasmodium berghei
To be published
2B4W
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BU of 2b4w by Molmil
Hypothetical protein from leishmania major
Descriptor: hypothetical protein, conserved
Authors:Holmes, M.A, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-09-26
Release date:2005-10-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Hypothetical protein from leishmania major
TO BE PUBLISHED
2F8M
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BU of 2f8m by Molmil
Ribose 5-phosphate isomerase from Plasmodium falciparum
Descriptor: PHOSPHATE ION, ribose 5-phosphate isomerase
Authors:Holmes, M.A, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-12-02
Release date:2005-12-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.087 Å)
Cite:Structure of ribose 5-phosphate isomerase from Plasmodium falciparum.
Acta Crystallogr.,Sect.F, 62, 2006
1X8U
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BU of 1x8u by Molmil
Crystal structure of Siderocalin (NGAL, Lipocalin 2) complexed with Carboxymycobactin T
Descriptor: CARBOXYMYCOBACTIN T, Neutrophil gelatinase-associated lipocalin
Authors:Holmes, M.A, Paulsene, W, Jide, X, Ratledge, C, Strong, R.K.
Deposit date:2004-08-18
Release date:2005-01-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Siderocalin (Lcn 2) Also Binds Carboxymycobactins, Potentially Defending against Mycobacterial Infections through Iron Sequestration
Structure, 13, 2005
1X71
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BU of 1x71 by Molmil
Crystal structure of Siderocalin (NGAL, Lipocalin 2) complexed with TRENCAM-3,2-HOPO, a cepabactin analogue
Descriptor: 2,3-DIHYDROXYBENZAMIDE, FE (III) ION, Neutrophil gelatinase-associated lipocalin
Authors:Holmes, M.A, Paulsene, W, Jide, X, Ratledge, C, Strong, R.K.
Deposit date:2004-08-12
Release date:2005-01-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Siderocalin (Lcn 2) Also Binds Carboxymycobactins, Potentially Defending against Mycobacterial Infections through Iron Sequestration
Structure, 13, 2005
1X89
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BU of 1x89 by Molmil
Crystal structure of Siderocalin (NGAL, Lipocalin 2) complexed with Carboxymycobactin S
Descriptor: CARBOXYMYCOBACTIN S, Neutrophil gelatinase-associated lipocalin
Authors:Holmes, M.A, Paulsene, W, Jide, X, Ratledge, C, Strong, R.K.
Deposit date:2004-08-17
Release date:2005-01-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Siderocalin (Lcn 2) Also Binds Carboxymycobactins, Potentially Defending against Mycobacterial Infections through Iron Sequestration
Structure, 13, 2005
2HMQ
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BU of 2hmq by Molmil
THE STRUCTURES OF MET AND AZIDOMET HEMERYTHRIN AT 1.66 ANGSTROMS RESOLUTION
Descriptor: ACETATE ION, HEMERYTHRIN, MU-OXO-DIIRON
Authors:Holmes, M.A, Stenkamp, R.E.
Deposit date:1990-10-18
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structures of met and azidomet hemerythrin at 1.66 A resolution.
J.Mol.Biol., 220, 1991
2HMZ
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BU of 2hmz by Molmil
THE STRUCTURES OF MET AND AZIDOMET HEMERYTHRIN AT 1.66 ANGSTROMS RESOLUTION
Descriptor: ACETATE ION, HEMERYTHRIN, MONOAZIDO-MU-OXO-DIIRON
Authors:Holmes, M.A, Stenkamp, R.E.
Deposit date:1990-10-18
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structures of met and azidomet hemerythrin at 1.66 A resolution.
J.Mol.Biol., 220, 1991
1HMD
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BU of 1hmd by Molmil
THE STRUCTURE OF DEOXY AND OXY HEMERYTHRIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor: ACETYL GROUP, HEMERYTHRIN, MU-OXO-DIIRON
Authors:Holmes, M.A, Letrong, I, Turley, S, Sieker, L.C, Stenkamp, R.E.
Deposit date:1990-10-18
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of deoxy and oxy hemerythrin at 2.0 A resolution.
J.Mol.Biol., 218, 1991
1HMO
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BU of 1hmo by Molmil
THE STRUCTURE OF DEOXY AND OXY HEMERYTHRIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor: ACETYL GROUP, HEMERYTHRIN, MU-OXO-DIIRON, ...
Authors:Holmes, M.A, Letrong, I, Turley, S, Sieker, L.C, Stenkamp, R.E.
Deposit date:1990-10-18
Release date:1992-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of deoxy and oxy hemerythrin at 2.0 A resolution.
J.Mol.Biol., 218, 1991
1JE6
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BU of 1je6 by Molmil
Structure of the MHC Class I Homolog MICB
Descriptor: MHC class I chain-related protein, SULFATE ION
Authors:Holmes, M.A, Li, P, Strong, R.K.
Deposit date:2001-06-15
Release date:2002-08-07
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies of allelic diversity of the MHC class I homolog MIC-B, a stress-inducible ligand for the activating immunoreceptor NKG2D.
J.Immunol., 169, 2002
4TLN
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BU of 4tln by Molmil
BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
Descriptor: CALCIUM ION, L-LEUCYL-HYDROXYLAMINE, THERMOLYSIN, ...
Authors:Matthews, B.W, Holmes, M.A.
Deposit date:1982-02-08
Release date:1982-05-26
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis.
Biochemistry, 20, 1981
7TLN
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BU of 7tln by Molmil
STRUCTURAL ANALYSIS OF THE INHIBITION OF THERMOLYSIN BY AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR
Descriptor: 2-(ACETYL-HYDROXY-AMINO)-4-METHYL-PENTANOIC ACID METHYL ESTER, CALCIUM ION, THERMOLYSIN, ...
Authors:Matthews, B.W, Holmes, M.A, Tronrud, D.E.
Deposit date:1983-01-27
Release date:1983-03-09
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor.
Biochemistry, 22, 1983
5TLN
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BU of 5tln by Molmil
BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
Descriptor: CALCIUM ION, HONH-BENZYLMALONYL-L-ALANYLGLYCINE-P-NITROANILIDE, THERMOLYSIN, ...
Authors:Matthews, B.W, Holmes, M.A.
Deposit date:1982-02-08
Release date:1982-05-26
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis.
Biochemistry, 20, 1981
3T43
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BU of 3t43 by Molmil
Crystal Structure of HIV Epitope-Scaffold 4E10_1XIZA_S0_006_C
Descriptor: HIV Epitope-Scaffold 4E10_1XIZA_S0_006_C
Authors:Holmes, M.A, Strong, R.K.
Deposit date:2011-07-25
Release date:2011-10-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:High-resolution structure prediction of a circular permutation loop.
Protein Sci., 20, 2011
3H3P
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BU of 3h3p by Molmil
Crystal structure of HIV epitope-scaffold 4E10 Fv complex
Descriptor: 4E10_S0_1TJLC_004_N, CALCIUM ION, Fv 4E10 heavy chain, ...
Authors:Holmes, M.A.
Deposit date:2009-04-16
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interactions between lipids and human anti-HIV antibody 4E10 can be reduced without ablating neutralizing activity
J.Virol., 84, 2010
3LEF
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BU of 3lef by Molmil
Crystal structure of HIV epitope-scaffold 4E10_S0_1Z6NA_001
Descriptor: 1,2-ETHANEDIOL, Uncharacterized protein 4E10_S0_1Z6NA_001 (T18)
Authors:Holmes, M.A.
Deposit date:2010-01-14
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LJN
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BU of 3ljn by Molmil
Ankyrin repeat protein from Leishmania major
Descriptor: hypothetical protein
Authors:Holmes, M.A, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2010-01-26
Release date:2010-02-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ankyrin repeat protein from Leishmania major
To be Published
3LF6
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BU of 3lf6 by Molmil
Crystal structure of HIV epitope-scaffold 4E10_1XIZA_S0_001_N
Descriptor: PHOSPHATE ION, Putative phosphotransferase system
Authors:Holmes, M.A.
Deposit date:2010-01-15
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LG7
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BU of 3lg7 by Molmil
Crystal structure of HIV epitope-scaffold 4E10_S0_1EZ3A_002_C
Descriptor: 4E10_S0_1EZ3A_002_C (T246), SULFATE ION
Authors:Holmes, M.A.
Deposit date:2010-01-19
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LH2
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BU of 3lh2 by Molmil
Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex
Descriptor: 4E10_1VI7A_S0_002_N (T88), Fv 4E10 heavy chain, Fv 4E10 light chain
Authors:Holmes, M.A.
Deposit date:2010-01-21
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LHP
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BU of 3lhp by Molmil
Crystal structure of HIV epitope-scaffold 4E10_D0_1ISEA_004_N 4E10 Fv complex
Descriptor: 1,2-ETHANEDIOL, 4E10_D0_1ISEA_004_N (T93), Fv 4E10 heavy chain, ...
Authors:Holmes, M.A.
Deposit date:2010-01-22
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010

 

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