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3ZXA
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BU of 3zxa by Molmil
Structure and Assembly of Turnip Crinkle Virus I. X-ray Crystallographic Structure Analysis at 3.2 A Resolution
Descriptor: CAPSID PROTEIN
Authors:Hogle, J.M, Maeda, A, Harrison, S.C.
Deposit date:2011-08-08
Release date:2012-02-08
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and Assembly of Turnip Crinkle Virus. I. X-Ray Crystallographic Structure Analysis at 3.2 A Resolution.
J.Mol.Biol., 191, 1986
6P9W
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BU of 6p9w by Molmil
Poliovirus (Type 1 Mahoney), receptor catalysed 135S particle map
Descriptor: VP1, VP2, VP3
Authors:Hogle, J.M, Filman, D.J, Shah, P.N.M.
Deposit date:2019-06-10
Release date:2020-06-10
Last modified:2020-10-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.
Plos Pathog., 16, 2020
6P9O
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BU of 6p9o by Molmil
Poliovirus 135S-like expanded particle in complex with a monoclonal antibody directed against the N-terminal extension of capsid protein VP1
Descriptor: VP1, VP2, VP3
Authors:Hogle, J.M, Filman, D.J, Shah, P.N.M.
Deposit date:2019-06-10
Release date:2020-06-10
Last modified:2020-10-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.
Plos Pathog., 16, 2020
6PSZ
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BU of 6psz by Molmil
Poliovirus (Type 1 Mahoney), heat-catalysed 135S particle
Descriptor: VP1, VP2, VP3
Authors:Hogle, J.M, Filman, D.J, Shah, P.N.M.
Deposit date:2019-07-14
Release date:2020-07-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.
Plos Pathog., 16, 2020
6Q0B
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BU of 6q0b by Molmil
Poliovirus (Type 1 Mahoney), receptor-catalysed 135S particle incubated with anti-VP1 mAb at RT for 1 hr
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Hogle, J.M, Filman, D.J, Shah, P.N.M.
Deposit date:2019-08-01
Release date:2020-08-05
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.
Plos Pathog., 16, 2020
2O0I
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BU of 2o0i by Molmil
crystal structure of the R185A mutant of the N-terminal domain of the Group B Streptococcus Alpha C protein
Descriptor: C protein alpha-antigen
Authors:Hogle, J.M, Filman, D.J, Baron, M.J, Madoff, L.C, Iglesias, A.
Deposit date:2006-11-27
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Identification of a glycosaminoglycan binding region of the alpha C protein that mediates entry of group B streptococci into host cells.
J.Biol.Chem., 282, 2007
1AR6
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BU of 1ar6 by Molmil
P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT V1160I +P1095S
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR9
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BU of 1ar9 by Molmil
P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT H2142Y
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AL2
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BU of 1al2 by Molmil
P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT V1160I
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-06-09
Release date:1997-11-19
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR7
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BU of 1ar7 by Molmil
P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT P1095S + H2142Y
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR8
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BU of 1ar8 by Molmil
P1/MAHONEY POLIOVIRUS, MUTANT P1095S
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1ASJ
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BU of 1asj by Molmil
P1/MAHONEY POLIOVIRUS, AT CRYOGENIC TEMPERATURE
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
2PLV
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BU of 2plv by Molmil
STRUCTURAL FACTORS THAT CONTROL CONFORMATIONAL TRANSITIONS AND SEROTYPE SPECIFICITY IN TYPE 3 POLIOVIRUS
Descriptor: HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP1), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP2), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP3), ...
Authors:Filman, D.J, Hogle, J.M.
Deposit date:1989-10-17
Release date:1989-10-17
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus
EMBO J., 8, 1989
4R0E
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BU of 4r0e by Molmil
Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Low-Fidelity Mutant 3Dpol H273R
Descriptor: RNA-directed RNA polymerase
Authors:Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M.
Deposit date:2014-07-30
Release date:2014-11-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Dynamics as a Contributor to Error-prone Replication by an RNA-dependent RNA Polymerase.
J.Biol.Chem., 289, 2014
1HXS
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BU of 1hxs by Molmil
CRYSTAL STRUCTURE OF MAHONEY STRAIN OF POLIOVIRUS AT 2.2A RESOLUTION
Descriptor: GENOME POLYPROTEIN, COAT PROTEIN VP1, COAT PROTEIN VP2, ...
Authors:Miller, S.T, Hogle, J.M, Filman, D.J.
Deposit date:2001-01-16
Release date:2002-01-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ab initio phasing of high-symmetry macromolecular complexes: successful phasing of authentic poliovirus data to 3.0 A resolution.
J.Mol.Biol., 307, 2001
8C6D
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BU of 8c6d by Molmil
Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate.
Descriptor: (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol, Genome polyprotein, Genome polyprotein (Fragment)
Authors:Kingston, N.J, Snowden, J.S, Stonehouse, N.J, Rowlands, D.J, Hogle, J.M.
Deposit date:2023-01-11
Release date:2023-02-22
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate.
Biorxiv, 2023
1PO2
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BU of 1po2 by Molmil
POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R77975, AN INHIBITOR OF VIRAL REPLICATION
Descriptor: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
Authors:Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
Deposit date:1997-01-08
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1PVC
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BU of 1pvc by Molmil
REFINEMENT OF THE SABIN STRAIN OF TYPE 3 POLIOVIRUS AT 2.4 ANGSTROMS AND THE CRYSTAL STRUCTURES OF ITS VARIANTS AT 2.9 ANGSTROMS RESOLUTION
Descriptor: MYRISTIC ACID, POLIOVIRUS TYPE 3, SABIN STRAIN, ...
Authors:Syed, R, Filman, D.J, Hogle, J.M.
Deposit date:1995-03-30
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Refinement of the Sabin Strain of Type 3 Poliovirus at 2.4 Angstroms and the Crystal Structures of its Variants at 2.9 Angstroms Resolution
To be Published
1PO1
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BU of 1po1 by Molmil
POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R80633, AN INHIBITOR OF VIRAL REPLICATION
Descriptor: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
Authors:Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
Deposit date:1997-01-08
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
5A3G
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BU of 5a3g by Molmil
Structure of herpesvirus nuclear egress complex subunit M50
Descriptor: M50
Authors:Leigh, K.E, Boeszoermenyi, A, Mansueto, M.S, Sharma, M, Filman, D.J, Coen, D.M, Wagner, G, Hogle, J.M, Arthanari, H.
Deposit date:2015-06-01
Release date:2015-07-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of a Herpesvirus Nuclear Egress Complex Subunit Reveals an Interaction Groove that is Essential for Viral Replication
Proc.Natl.Acad.Sci.USA, 112, 2015
1VBD
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BU of 1vbd by Molmil
POLIOVIRUS (TYPE 1, MAHONEY STRAIN) COMPLEXED WITH R78206
Descriptor: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
Authors:Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
Deposit date:1996-01-02
Release date:1996-07-11
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1A92
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BU of 1a92 by Molmil
OLIGOMERIZATION DOMAIN OF HEPATITIS DELTA ANTIGEN
Descriptor: DELTA ANTIGEN
Authors:Zuccola, H.J, Hogle, J.M.
Deposit date:1998-04-15
Release date:1999-06-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of the oligomerization of hepatitis delta antigen.
Structure, 6, 1998
1VBA
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BU of 1vba by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R78206
Descriptor: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
Authors:Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
Deposit date:1996-01-02
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBB
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BU of 1vbb by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R80633
Descriptor: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
Authors:Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
Deposit date:1996-01-02
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBC
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BU of 1vbc by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R77975
Descriptor: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
Authors:Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
Deposit date:1996-01-02
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994

 

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