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2H4J
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BU of 2h4j by Molmil
Sir2-deacetylated peptide (from enzymatic turnover in crystal)
Descriptor: 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, Cellular tumor antigen p53, NAD-dependent deacetylase, ...
Authors:Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C.
Deposit date:2006-05-24
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide.
Structure, 14, 2006
2H59
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BU of 2h59 by Molmil
Sir2 H116A-deacetylated p53 peptide-3'-o-acetyl ADP ribose
Descriptor: (2S,3S,4R,5S)-2-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-4,5-DIHYDROXYTETRAHYDROFURAN-3-YL ACETATE, ADENOSINE-5-DIPHOSPHORIBOSE, Cellular tumor antigen p53, ...
Authors:Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C.
Deposit date:2006-05-25
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide.
Structure, 14, 2006
2H4F
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BU of 2h4f by Molmil
Sir2-p53 peptide-NAD+
Descriptor: Cellular tumor antigen p53, NAD-dependent deacetylase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C.
Deposit date:2006-05-24
Release date:2006-09-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide.
Structure, 14, 2006
2H4H
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BU of 2h4h by Molmil
Sir2 H116Y mutant-p53 peptide-NAD
Descriptor: Cellular tumor antigen p53, NAD-dependent deacetylase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C.
Deposit date:2006-05-24
Release date:2006-09-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide.
Structure, 14, 2006
3D4B
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BU of 3d4b by Molmil
Crystal structure of Sir2Tm in complex with Acetyl p53 peptide and DADMe-NAD+
Descriptor: 5'-O-[(R)-{[(R)-{[(3R,4R)-1-(3-carbamoylbenzyl)-4-hydroxypyrrolidin-3-yl]methoxy}(hydroxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine, Acetyl P53 peptide, NAD-dependent deacetylase, ...
Authors:Hawse, W.F, Hoff, K.G, Fatkins, D, Daines, A, Zubkova, O.V, Schramm, V.L, Zheng, W, Wolberger, C.
Deposit date:2008-05-14
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into intermediate steps in the Sir2 deacetylation reaction.
Structure, 16, 2008
3D81
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BU of 3d81 by Molmil
Sir2-S-alkylamidate complex crystal structure
Descriptor: NAD-dependent deacetylase, S-alkylamidate intermediate, ZINC ION
Authors:Hawse, W.F, Hoff, K.G, Fatkins, D, Daines, A, Zubkova, O.V, Schramm, V.L, Zheng, W, Wolberger, C.
Deposit date:2008-05-22
Release date:2008-09-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into intermediate steps in the Sir2 deacetylation reaction.
Structure, 16, 2008

217705

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