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1Z8G
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BU of 1z8g by Molmil
Crystal structure of the extracellular region of the transmembrane serine protease hepsin with covalently bound preferred substrate.
Descriptor: ACE-LYS-GLN-LEU-ARG-Chloromethylketone, Serine protease hepsin
Authors:Herter, S, Piper, D.E, Aaron, W, Gabriele, T, Cutler, G, Cao, P, Bhatt, A.S, Choe, Y, Craik, C.S, Walker, N, Meininger, D, Hoey, T, Austin, R.J.
Deposit date:2005-03-30
Release date:2005-05-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers
Biochem.J., 390, 2005

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