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3VUU
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CRYSTAL STRUCTURE OF THE MEROZOITE SURFACE PROTEIN MSPDBL2 FROM P. FALCIPARUM
Descriptor:Erythrocyte membrane protein, putative, CHLORIDE ION
Authors:Czabotar, P.E., Hodder, A.N., Clarke, O.B., Lin, C.S., Smith, B.J., Cowman, A.F.
Deposit date:2012-07-09
Release date:2012-08-08
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2.093 Å)
Cite:Insights into Duffy binding-like domains through the crystal structure and function of the merozoite surface protein MSPDBL2 from Plasmodium falciparum
J.Biol.Chem., 287, 2012
3VUV
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CRYSTAL STRUCTURE OF THE MEROZOITE SURFACE PROTEIN MSPDBL2 FROM P. FALCIPARUM BOUND TO ZINC
Descriptor:Erythrocyte membrane protein, putative, ZINC ION
Authors:Czabotar, P.E., Hodder, A.N., Clarke, O.B., Lin, C.S., Smith, B.J., Cowman, A.F.
Deposit date:2012-07-09
Release date:2012-08-08
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2.114 Å)
Cite:Insights into Duffy binding-like domains through the crystal structure and function of the merozoite surface protein MSPDBL2 from Plasmodium falciparum
J.Biol.Chem., 287, 2012
4ZL4
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PLASMEPSIN V FROM PLASMODIUM VIVAX BOUND TO A TRANSITION STATE MIMETIC (WEHI-842)
Descriptor:Aspartic protease PM5, N-[(benzyloxy)carbonyl]-O-carbamimidamido-L-homoseryl-N-{(3S,4S)-3-hydroxy-6-methyl-1-oxo-1-[(2-phenylethyl)amino]heptan-4-yl}-L-valinamide, SULFATE ION, ...
Authors:Czabotar, P.E., Hodder, A.N., Smith, B.J., Sleebs, B.E., Gazdic, M., Boddey, J.A., Cowman, A.F.
Deposit date:2015-05-01
Release date:2015-07-15
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes.
Nat.Struct.Mol.Biol., 22, 2015
6C4G
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PLASMEPSIN V FROM PLASMODIUM VIVAX BOUND TO A TRANSITION STATE MIMETIC (WEHI-601)
Descriptor:Aspartic protease PM5, N-ACETYL-D-GLUCOSAMINE, benzyl [(6S,7S,10S,13S,18Z)-18-amino-10-cyclohexyl-6-hydroxy-18-imino-7-(2-methylpropyl)-4,9,12-trioxo-1-phenyl-16-oxa-3,8,11,17-tetraazaoctadecan-13-yl]carbamate, ...
Authors:Czabotar, P.E., Hodder, A.N., Nguyen, W., Sleebs, B.E., Boddey, J.A., Cowman, A.F.
Deposit date:2018-01-11
Release date:2018-06-13
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P2position of PEXEL peptidomimetics.
Eur J Med Chem, 154, 2018
2WBF
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CRYSTAL STRUCTURE ANALYSIS OF SERA5E FROM PLASMODIUM FALCIPARUM WITH LOOP 690-700 ORDERED
Descriptor:SERINE-REPEAT ANTIGEN PROTEIN, DIMETHYL SULFOXIDE, CALCIUM ION, ...
Authors:Smith, B.J., Malby, R.L., Colman, P.M., Clarke, O.B.
Deposit date:2009-02-27
Release date:2009-03-31
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the protease-like antigen Plasmodium falciparum SERA5 and its noncanonical active-site serine.
J. Mol. Biol., 392, 2009
3CH2
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CRYSTAL STRUCTURE ANALYSIS OF SERA5E FROM PLASMODIUM FALCIPARUM
Descriptor:Serine-repeat antigen protein, CALCIUM ION
Authors:Smith, B.J., Malby, R.L., Colman, P.M., Clarke, O.B.
Deposit date:2008-03-07
Release date:2008-03-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Insights into the Protease-like Antigen Plasmodium falciparum SERA5 and Its Noncanonical Active-Site Serine
J.Mol.Biol., 392, 2009
3CH3
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CRYSTAL STRUCTURE ANALYSIS OF SERA5E FROM PLASMODIUM FALCIPARUM
Descriptor:Serine-repeat antigen protein, POTASSIUM ION, DIHYDROGENPHOSPHATE ION
Authors:Smith, B.J., Malby, R.L., Colman, P.M., Clarke, O.B.
Deposit date:2008-03-07
Release date:2008-03-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural Insights into the Protease-like Antigen Plasmodium falciparum SERA5 and Its Noncanonical Active-Site Serine
J.Mol.Biol., 392, 2009
1HN6
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SOLUTION STRUCTURE OF PLASMODIUM FALCIPARUM APICAL MEMBRANE ANTIGEN 1 (RESIDUES 436-545)
Descriptor:APICAL MEMBRANE ANTIGEN 1
Authors:Nair, M.
Deposit date:2000-12-07
Release date:2002-10-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of domain III of the blood-stage malaria vaccine candidate, Plasmodium falciparum apical membrane antigen 1 (AMA1).
J.Mol.Biol., 322, 2002
2I54
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PHOSPHOMANNOMUTASE FROM LEISHMANIA MEXICANA
Descriptor:Phosphomannomutase, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Smith, B.J.
Deposit date:2006-08-24
Release date:2007-04-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Leishmania mexicana phosphomannomutase highlights similarities with human isoforms
J.Mol.Biol., 363, 2006
2I55
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COMPLEX OF GLUCOSE-1,6-BISPHOSPHATE WITH PHOSPHOMANNOMUTASE FROM LEISHMANIA MEXICANA
Descriptor:Phosphomannomutase, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Smith, B.J.
Deposit date:2006-08-24
Release date:2007-04-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of Leishmania mexicana phosphomannomutase highlights similarities with human isoforms
J.Mol.Biol., 363, 2006
6MPV
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF PLASMODIUM FALCIPARUM RH5/CYRPA/RIPR INVASION COMPLEX
Descriptor:Cysteine-rich protective antigen, Reticulocyte binding protein 5, PfRipr
Authors:Wilson, W., Zhiheng, Y., Cowman, A.F.
Deposit date:2018-10-08
Release date:2018-12-12
Last modified:2019-01-16
Method:ELECTRON MICROSCOPY (7.17 Å)
Cite:Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex.
Nature, 565, 2019