Author results

1RVW
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R STATE HUMAN HEMOGLOBIN [ALPHA V96W], CARBONMONOXY
Descriptor:HEMOGLOBIN, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Puius, Y.A., Zou, M., Ho, N.T., Ho, C., Almo, S.C.
Deposit date:1997-03-20
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp).
Biochemistry, 37, 1998
1VWT
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T STATE HUMAN HEMOGLOBIN [ALPHA V96W], ALPHA AQUOMET, BETA DEOXY
Descriptor:HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Puius, Y.A., Zou, M., Ho, N.T., Ho, C., Almo, S.C.
Deposit date:1997-03-20
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp).
Biochemistry, 37, 1998
4LLD
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STRUCTURE OF WILD-TYPE IGG1 ANTIBODY HEAVY CHAIN CONSTANT DOMAIN 1 AND LIGHT CHAIN LAMBDA CONSTANT DOMAIN (IGG1 CH1:CLAMBDA) AT 1.19A
Descriptor:Ig gamma-1 chain C region, Ig lambda-2 chain C region
Authors:Pustilnik, A., Lewis, S.M., Wu, X., Sereno, A., Huang, F., Guntas, G., Leaver-Fay, A., Smith, E.M., Ho, C., Hansen-Estruch, C., Chamberlain, A.K., Truhlar, S.M., Kuhlman, B., Demarest, S.J., Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLM
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STRUCTURE OF REDESIGNED IGG1 FIRST CONSTANT AND LAMBDA DOMAINS (CH1:CLAMBDA CONSTANT REDESIGN 1, CRD1) AT 1.75A
Descriptor:Ig gamma-1 chain C region, Ig lambda-2 chain C region
Authors:Pustilnik, A., Lewis, S.M., Wu, X., Sereno, A., Huang, F., Guntas, G., Leaver-Fay, A., Smith, E.M., Ho, C., Hansen-Estruch, C., Chamberlain, A.K., Truhlar, S.M., Kuhlman, B., Demarest, S.J., Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLQ
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STRUCTURE OF REDESIGNED IGG1 FIRST CONSTANT AND LAMBDA DOMAINS (CH1:CLAMBDA CONSTANT REDESIGN 2 BETA, CRD2B) AT 1.42A
Descriptor:mutated CH1, mutated light chain Clambda, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE
Authors:Pustilnik, A., Lewis, S.M., Wu, X., Sereno, A., Huang, F., Guntas, G., Leaver-Fay, A., Smith, E.M., Ho, C., Hansen-Estruch, C., Chamberlain, A.K., Truhlar, S.M., Kuhlman, B., Demarest, S.J., Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLU
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STRUCTURE OF PERTUZUMAB FAB WITH LIGHT CHAIN CLAMBDA AT 2.16A
Descriptor:PERTUZUMAB FAB Heavy chain, Light chain CLAMBDA, SULFATE ION, ...
Authors:Pustilnik, A., Lewis, S.M., Wu, X., Sereno, A., Huang, F., Guntas, G., Leaver-Fay, A., Smith, E.M., Ho, C., Hansen-Estruch, C., Chamberlain, A.K., Truhlar, S.M., Kuhlman, B., Demarest, S.J., Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLW
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CRYSTAL STRUCTURE OF PERTUZUMAB CLAMBDA FAB WITH VARIABLE DOMAIN REDESIGN (VRD2) AT 1.95A
Descriptor:mutated Pertuzumab Fab heavy chain, light chain Clambda, SULFATE ION
Authors:Pustilnik, A., Lewis, S.M., Wu, X., Sereno, A., Huang, F., Guntas, G., Leaver-Fay, A., Smith, E.M., Ho, C., Hansen-Estruch, C., Chamberlain, A.K., Truhlar, S.M., Kuhlman, B., Demarest, S.J., Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLY
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CRYSTAL STRUCTURE OF PERTUZUMAB CLAMBDA FAB WITH VARIABLE AND CONSTANT DOMAIN REDESIGNS (VRD2 AND CRD2) AT 1.6A
Descriptor:mutated Pertuzumab Fab heavy chain, light chain Clambda, GLYCEROL, ...
Authors:Pustilnik, A., Lewis, S.M., Wu, X., Sereno, A., Huang, F., Guntas, G., Leaver-Fay, A., Smith, E.M., Ho, C., Hansen-Estruch, C., Chamberlain, A.K., Truhlar, S.M., Kuhlman, B., Demarest, S.J., Atwell, S.
Deposit date:2013-07-09
Release date:2014-01-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
1F0X
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CRYSTAL STRUCTURE OF D-LACTATE DEHYDROGENASE, A PERIPHERAL MEMBRANE RESPIRATORY ENZYME.
Descriptor:D-LACTATE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Dym, O., Pratt, E.A., Ho, C., Eisenberg, D.
Deposit date:2000-05-17
Release date:2000-08-23
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzyme.
Proc.Natl.Acad.Sci.USA, 97, 2000
3KB2
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CRYSTAL STRUCTURE OF YORR PROTEIN IN COMPLEX WITH PHOSPHORYLATED GDP FROM BACILLUS SUBTILIS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR256
Descriptor:SPBc2 prophage-derived uncharacterized protein yorR, GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Forouhar, F., Friedman, D., Seetharaman, J., Janjua, J., Xiao, R., Cunningham, K., Ma, L., Ho, C., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-10-20
Release date:2009-10-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Northeast Structural Genomics Consortium Target SR256
To be Published
3VRE
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THE CRYSTAL STRUCTURE OF HEMOGLOBIN FROM WOOLLY MAMMOTH IN THE DEOXY FORM
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE
Authors:Noguchi, H., Campbell, K.L., Ho, C., Park, S.-Y., Tame, J.R.H.
Deposit date:2012-04-09
Release date:2012-11-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
3VRF
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THE CRYSTAL STRUCTURE OF HEMOGLOBIN FROM WOOLLY MAMMOTH IN THE CARBONMONOXY FORMS
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Noguchi, H., Campbell, K.L., Ho, C., Park, S.-Y., Tame, J.R.H.
Deposit date:2012-04-09
Release date:2012-11-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
3VRG
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THE CRYSTAL STRUCTURE OF HEMOGLOBIN FROM WOOLLY MAMMOTH IN THE MET FORM
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Noguchi, H., Campbell, K.L., Ho, C., Park, S.-Y., Tame, J.R.H.
Deposit date:2012-04-09
Release date:2012-11-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
6E10
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PTEX CORE COMPLEX IN THE ENGAGED (EXTENDED) STATE
Descriptor:Heat shock protein 101, Exported protein 2, Translocon component PTEX150, ...
Authors:Ho, C., Lai, M., Zhou, Z.H.
Deposit date:2018-07-08
Release date:2018-08-22
Last modified:2018-09-12
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Malaria parasite translocon structure and mechanism of effector export.
Nature, 561, 2018
6E11
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PTEX CORE COMPLEX IN THE RESETTING (COMPACT) STATE
Descriptor:Unknown (Claw), Heat shock protein 101, Exported protein 2, ...
Authors:Ho, C., Lai, M., Zhou, Z.H.
Deposit date:2018-07-08
Release date:2018-08-22
Last modified:2018-09-12
Method:ELECTRON MICROSCOPY (4.23 Å)
Cite:Malaria parasite translocon structure and mechanism of effector export.
Nature, 561, 2018
2KL5
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SOLUTION NMR STRUCTURE OF PROTEIN YUTD FROM B.SUBTILIS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR232
Descriptor:Uncharacterized protein yutD
Authors:Liu, G., Hamilton, K., Xiao, R., Ciccosanti, C., Ho, C.J., Everett, J., Nair, R., Acton, T., Rost, B., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-06-30
Release date:2009-07-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution NMR Structure of protein yutD from B.subtilis, Northeast Structural Genomics Consortium Target Target SR232
To be Published
2GZP
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SOLUTION NMR STRUCTURE OF Q8ZP25 FROM SALMONELLA TYPHIMURIUM LT2; NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET STR70
Descriptor:putative chaperone
Authors:Parish, D., Liu, G., Shen, Y., Ho, C., Cunningham, K., Xiao, R., Swapna, G.V.T., Acton, T.B., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-05-11
Release date:2006-06-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution NMR structure of Q8ZP24 from Salmonella typhimurium LT2.
To be Published
2M6Z
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REFINED SOLUTION STRUCTURE OF HUMAN ADULT HEMOGLOBIN IN THE CARBONMONOXY FORM
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, HEME C
Authors:Fan, J.S., Yang, D., Choy, W.Y.
Deposit date:2013-04-15
Release date:2013-09-18
Method:SOLUTION NMR
Cite:Solution structure and dynamics of human hemoglobin in the carbonmonoxy form
Biochemistry, 52, 2013
4BU2
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60S RIBOSOMAL PROTEIN L27A HISTIDINE HYDROXYLASE (MINA53) IN COMPLEX WITH NI(II) AND 2-OXOGLUTARATE (2OG)
Descriptor:BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA, NICKEL (II) ION, 2-OXOGLUTARIC ACID, ...
Authors:Chowdhury, R., Clifton, I.J., McDonough, M.A., Ng, S.S., Pilka, E., Oppermann, U., Schofield, C.J.
Deposit date:2013-06-19
Release date:2014-05-14
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
4BXF
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60S RIBOSOMAL PROTEIN L27A HISTIDINE HYDROXYLASE (MINA53 Y209C) IN COMPLEX WITH MN(II), 2-OXOGLUTARATE (2OG) AND 60S RIBOSOMAL PROTEIN L27A (RPL27A G37C) PEPTIDE FRAGMENT
Descriptor:BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA, 60S RIBOSOMAL PROTEIN L27A, MANGANESE (II) ION, ...
Authors:Chowdhury, R., Schofield, C.J.
Deposit date:2013-07-10
Release date:2014-05-14
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
4CCJ
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60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE (NO66) IN APO FORM
Descriptor:BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, 1,2-ETHANEDIOL
Authors:Chowdhury, R., Ge, W., Clifton, I.J., Schofield, C.J.
Deposit date:2013-10-23
Release date:2014-05-14
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
4CCK
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60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE (NO66) IN COMPLEX WITH MN(II) AND N-OXALYLGLYCINE (NOG)
Descriptor:BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, MANGANESE (II) ION, N-OXALYLGLYCINE, ...
Authors:Chowdhury, R., Ge, W., Clifton, I.J., Schofield, C.J.
Deposit date:2013-10-23
Release date:2014-05-14
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
4CCM
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60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE (NO66) IN COMPLEX WITH MN(II), N-OXALYLGLYCINE (NOG) AND 60S RIBOSOMAL PROTEIN L8 (RPL8 G220C) PEPTIDE FRAGMENT (COMPLEX-1)
Descriptor:BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, 60S RIBOSOMAL PROTEIN L8, MANGANESE (II) ION, ...
Authors:Chowdhury, R., Schofield, C.J.
Deposit date:2013-10-23
Release date:2014-05-14
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
4CCN
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60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE (NO66 L299C/C300S) IN COMPLEX WITH MN(II), N-OXALYLGLYCINE (NOG) AND 60S RIBOSOMAL PROTEIN L8 (RPL8 G220C) PEPTIDE FRAGMENT (COMPLEX-2)
Descriptor:BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, 60S RIBOSOMAL PROTEIN L8, MANGANESE (II) ION, ...
Authors:Chowdhury, R., Schofield, C.J.
Deposit date:2013-10-23
Release date:2014-05-14
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
4CCO
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60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE (NO66 S373C) IN COMPLEX WITH MN(II), N-OXALYLGLYCINE (NOG) AND 60S RIBOSOMAL PROTEIN L8 (RPL8 G214C) PEPTIDE FRAGMENT (COMPLEX-3)
Descriptor:BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, 60S RIBOSOMAL PROTEIN L8, MANGANESE (II) ION, ...
Authors:Chowdhury, R., Schofield, C.J.
Deposit date:2013-10-23
Release date:2014-05-14
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
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