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7DY0
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BU of 7dy0 by Molmil
1.93 A cryo-EM structure of streptavidin
Descriptor: Streptavidin
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Kikkawa, M, Nureki, O.
Deposit date:2021-01-20
Release date:2021-02-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (1.93 Å)
Cite:1.93 A cryo-EM structure of streptavidin
To Be Published
7EFD
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BU of 7efd by Molmil
1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40 e/A^2 total dose)
Descriptor: BIOTIN, Streptavidin
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O.
Deposit date:2021-03-21
Release date:2021-04-28
Method:ELECTRON MICROSCOPY (1.77 Å)
Cite:1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40e/A^2 total dose)
To Be Published
7EFC
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BU of 7efc by Molmil
1.70 A cryo-EM structure of streptavidin
Descriptor: BIOTIN, Streptavidin
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O.
Deposit date:2021-03-21
Release date:2021-04-28
Method:ELECTRON MICROSCOPY (1.7 Å)
Cite:1.70 A cryo-EM structure of streptavidin using all frames (corresponding to 70 e/A^2 total dose)
To Be Published
8HB0
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BU of 8hb0 by Molmil
Structure of human SGLT2-MAP17 complex with TA1887
Descriptor: (2R,3R,4S,5S,6R)-2-[3-[(4-cyclopropylphenyl)methyl]-4-fluoranyl-indol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ...
Authors:Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O.
Deposit date:2022-10-27
Release date:2023-11-01
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter.
Nat.Struct.Mol.Biol., 31, 2024
8HDH
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BU of 8hdh by Molmil
Structure of human SGLT2-MAP17 complex with Canagliflozin
Descriptor: (2~{S},3~{R},4~{R},5~{S},6~{R})-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methyl-phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ...
Authors:Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O.
Deposit date:2022-11-04
Release date:2023-11-08
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter.
Nat.Struct.Mol.Biol., 31, 2024
8HG7
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BU of 8hg7 by Molmil
Structure of human SGLT2-MAP17 complex with Sotagliflozin
Descriptor: (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[(4-ethoxyphenyl)methyl]phenyl]-6-methylsulfanyl-oxane-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ...
Authors:Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O.
Deposit date:2022-11-14
Release date:2023-11-15
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter.
Nat.Struct.Mol.Biol., 31, 2024
8HEZ
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BU of 8hez by Molmil
Structure of human SGLT2-MAP17 complex with Dapagliflozin
Descriptor: (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ...
Authors:Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O.
Deposit date:2022-11-09
Release date:2023-11-15
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter.
Nat.Struct.Mol.Biol., 31, 2024
8HIN
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BU of 8hin by Molmil
Structure of human SGLT2-MAP17 complex with Phlorizin
Descriptor: 1-[2-[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,6-bis(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ...
Authors:Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O.
Deposit date:2022-11-21
Release date:2023-11-22
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter.
Nat.Struct.Mol.Biol., 31, 2024
6K7H
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BU of 6k7h by Molmil
Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state class2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ...
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-06-07
Release date:2019-08-28
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Science, 365, 2019
6K7I
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BU of 6k7i by Molmil
Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state class2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ...
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-06-07
Release date:2019-08-28
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Science, 365, 2019
6K7N
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BU of 6k7n by Molmil
Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1P state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ...
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-06-07
Release date:2019-08-28
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Science, 365, 2019
6K7J
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BU of 6k7j by Molmil
Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state class1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ...
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-06-07
Release date:2019-08-28
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Science, 365, 2019
6K7K
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BU of 6k7k by Molmil
Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ADP-Pi state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, ...
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-06-07
Release date:2019-08-28
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Science, 365, 2019
6K7G
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BU of 6k7g by Molmil
Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state class1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ...
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-06-07
Release date:2019-08-28
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Science, 365, 2019
6K7L
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BU of 6k7l by Molmil
Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E2P state class2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BERYLLIUM TRIFLUORIDE ION, CHOLESTEROL HEMISUCCINATE, ...
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-06-07
Release date:2019-08-28
Last modified:2021-02-03
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Science, 365, 2019
6K7M
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BU of 6k7m by Molmil
Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E2Pi-PL state)
Descriptor: (2~{S})-2-azanyl-3-[[(2~{R})-3-hexadecanoyloxy-2-[(~{Z})-octadec-9-enoyl]oxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-06-07
Release date:2019-08-28
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Science, 365, 2019
5H36
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BU of 5h36 by Molmil
Crystal structures of the TRIC trimeric intracellular cation channel orthologue from Rhodobacter sphaeroides
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Uncharacterized protein TRIC
Authors:Kasuya, G, Hiraizumi, M, Hattori, M, Nureki, O.
Deposit date:2016-10-20
Release date:2017-01-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.409 Å)
Cite:Crystal structures of the TRIC trimeric intracellular cation channel orthologues
Cell Res., 26, 2016
5H35
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BU of 5h35 by Molmil
Crystal structures of the TRIC trimeric intracellular cation channel orthologue from Sulfolobus solfataricus
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Fab Heavy Chain, Fab Light Chain, ...
Authors:Kasuya, G, Hiraizumi, M, Hattori, M, Nureki, O.
Deposit date:2016-10-20
Release date:2017-01-11
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.642 Å)
Cite:Crystal structures of the TRIC trimeric intracellular cation channel orthologues
Cell Res., 26, 2016
6LMU
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BU of 6lmu by Molmil
Cryo-EM structure of the human CALHM2
Descriptor: Calcium homeostasis modulator protein 2
Authors:Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-12-26
Release date:2020-07-29
Last modified:2020-09-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies.
Sci Adv, 6, 2020
6LMX
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BU of 6lmx by Molmil
Cryo-EM structure of the CALHM chimeric construct (9-mer)
Descriptor: Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2
Authors:Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-12-26
Release date:2020-07-29
Last modified:2020-09-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies.
Sci Adv, 6, 2020
6LMV
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BU of 6lmv by Molmil
Cryo-EM structure of the C. elegans CLHM-1
Descriptor: Calcium homeostasis modulator protein
Authors:Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-12-26
Release date:2020-07-29
Last modified:2020-09-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies.
Sci Adv, 6, 2020
6LMW
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BU of 6lmw by Molmil
Cryo-EM structure of the CALHM chimeric construct (8-mer)
Descriptor: Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2
Authors:Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-12-26
Release date:2020-07-29
Last modified:2020-09-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies.
Sci Adv, 6, 2020
6LMT
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BU of 6lmt by Molmil
Cryo-EM structure of the killifish CALHM1
Descriptor: CHOLESTEROL HEMISUCCINATE, Calcium homeostasis modulator 1
Authors:Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O.
Deposit date:2019-12-26
Release date:2020-07-29
Last modified:2020-09-09
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies.
Sci Adv, 6, 2020

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PDB entries from 2024-03-27

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