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1AX6
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SOLUTION STRUCTURE OF THE [AF]-C8-DG ADDUCT OPPOSITE A-2 DELETION SITE IN THE NARI HOT SPOT SEQUENCE CONTEXT; NMR, 6 STRUCTURES
Descriptor:DNA DUPLEX D(CTCGGC-[AF]G-CCATC)D(GATGGCCGAG), 2-AMINOFLUORENE
Authors:Mao, B., Gorin, A.A., Gu, Z., Hingerty, B.E., Broyde, S., Patel, D.J.
Deposit date:1997-10-30
Release date:1998-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the aminofluorene-intercalated conformer of the syn [AF]-C8-dG adduct opposite a--2 deletion site in the NarI hot spot sequence context.
Biochemistry, 36, 1997
1AX7
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SOLUTION STRUCTURE OF THE [AF]-C8-DG ADDUCT POSITIONED AT A TEMPLATE-PRIMER JUNCTION, NMR, 6 STRUCTURES
Descriptor:DNA DUPLEX D(AAC-[AF]G-CTACCATCC)D(GGATGGTAG), 2-AMINOFLUORENE
Authors:Mao, B., Gu, Z., Gorin, A.A., Hingerty, B.E., Broyde, S., Patel, D.J.
Deposit date:1997-10-30
Release date:1998-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the aminofluorene-stacked conformer of the syn [AF]-C8-dG adduct positioned at a template-primer junction.
Biochemistry, 36, 1997
1AXL
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SOLUTION CONFORMATION OF THE (-)-TRANS-ANTI-[BP]DG ADDUCT OPPOSITE A DELETION SITE IN DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG), NMR, 6 STRUCTURES
Descriptor:DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG), 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE
Authors:Feng, B., Gorin, A.A., Kolbanovskiy, A., Hingerty, B.E., Geacintov, N.E., Broyde, S., Patel, D.J.
Deposit date:1997-10-16
Release date:1998-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
Biochemistry, 36, 1997
1AXO
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STRUCTURAL ALIGNMENT OF THE (+)-TRANS-ANTI-[BP]DG ADDUCT POSITIONED OPPOSITE DC AT A DNA TEMPLATE-PRIMER JUNCTION, NMR, 6 STRUCTURES
Descriptor:DNA DUPLEX D(AAC-[BP]G-CTACCATCC)D(GGATGGTAGC), 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE
Authors:Feng, B., Gorin, A.A., Hingerty, B.E., Geacintov, N.E., Broyde, S., Patel, D.J.
Deposit date:1997-10-16
Release date:1998-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction.
Biochemistry, 36, 1997
1AXU
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SOLUTION NMR STRUCTURE OF THE [AP]DG ADDUCT OPPOSITE DA IN A DNA DUPLEX, NMR, 9 STRUCTURES
Descriptor:DNA DUPLEX D(CCATC-[AP]G-CTACC)D(GGTAGAGATGG), N-1-AMINOPYRENE
Authors:Gu, Z., Gorin, A.A., Krishnasami, R., Hingerty, B.E., Basu, A.K., Broyde, S., Patel, D.J.
Deposit date:1997-10-21
Release date:1998-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex.
Biochemistry, 38, 1999
1AXV
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SOLUTION NMR STRUCTURE OF THE [BP]DA ADDUCT OPPOSITE DT IN A DNA DUPLEX, 6 STRUCTURES
Descriptor:DNA DUPLEX D(CTCTC-[BP]A-CTTCC)D(GGAAGTGAGAG), 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE
Authors:Mao, B., Gu, Z., Gorin, A.A., Chen, J., Hingerty, B.E., Amid, S., Broyde, S., Geacintov, N.E., Patel, D.J.
Deposit date:1997-10-21
Release date:1998-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex.
Biochemistry, 38, 1999
1C0Y
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SOLUTION STRUCTURE OF THE [AF]-C8-DG ADDUCT POSITIONED OPPOSITE DA AT A TEMPLATE-PRIMER JUNCTION
Descriptor:DNA (5'-D(*AP*AP*CP*GP*CP*TP*AP*CP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*GP*GP*TP*AP*GP*C)-3'), 2-AMINOFLUORENE
Authors:Gu, Z., Gorin, A., Hingerty, B.E., Broyde, S., Patel, D.J.
Deposit date:1999-07-19
Release date:1999-08-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of aminofluorene [AF]-stacked conformers of the syn [AF]-C8-dG adduct positioned opposite dC or dA at a template-primer junction.
Biochemistry, 38, 1999
1FJ5
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TAMOXIFEN-DNA ADDUCT
Descriptor:DNA (5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'), (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINIUM
Authors:Shimotakahara, S., Gorin, A., Kolbanovskiy, A., Kettani, A., Hingerty, B.E., Amin, S., Broyde, S., Geacintov, N., Patel, D.J.
Deposit date:2000-08-07
Release date:2000-09-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Accomodation of S-cis-tamoxifen-N(2)-guanine adduct within a bent and widened DNA minor groove.
J.Mol.Biol., 302, 2000
1HWV
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MOLECULAR TOPOLOGY OF POLYCYCLIC AROMATIC CARCINOGENS DETERMINES DNA ADDUCT CONFORMATION: A LINK TO TUMORIGENIC ACTIVITY
Descriptor:5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3', (1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL
Authors:Patel, D.J., Lin, C.H., Geacintov, N.E., Broyde, S., Huang, X., Kolbanovskii, A., Hingerty, B.E., Amin, S.
Deposit date:2001-01-10
Release date:2001-03-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
J.Mol.Biol., 306, 2001
1HX4
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MOLECULAR TOPOLOGY OF POLYCYCLIC AROMATIC CARCINOGENS DETERMINES DNA ADDUCT CONFORMATION: A LINK TO TUMORIGENIC ACTIVITY
Descriptor:5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3', (1R)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL
Authors:Patel, D.J., Lin, C.H., Geacintov, N.E., Broyde, S., Huang, X., Kolbanovskii, A., Hingerty, B.E., Amin, S.
Deposit date:2001-01-11
Release date:2001-03-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
J.Mol.Biol., 306, 2001
1PYJ
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SOLUTION STRUCTURE OF AN O6-[4-OXO-4-(3-PYRIDYL)BUTYL]GUANINE ADDUCT IN AN 11MER DNA DUPLEX
Descriptor:5'-D(*CP*CP*AP*TP*AP*TP*GP*GP*CP*CP*C)-3', 5'-D*GP*GP*GP*CP*CP*AP*TP*AP*TP*GP*G)-3'
Authors:Peterson, L.A., Vu, C., Hingerty, B.E., Broyde, S., Cosman, M.
Deposit date:2003-07-09
Release date:2004-04-20
Last modified:2014-08-06
Method:SOLUTION NMR
Cite:Solution structure of an O6-[4-oxo-4-(3-pyridyl)butyl]guanine adduct in an 11 mer DNA duplex: evidence for formation of a base triplex.
Biochemistry, 42, 2003
1Y9H
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METHYLATION OF CYTOSINE AT C5 IN A CPG SEQUENCE CONTEXT CAUSES A CONFORMATIONAL SWITCH OF A BENZO[A]PYRENE DIOL EPOXIDE-N2-GUANINE ADDUCT IN DNA FROM A MINOR GROOVE ALIGNMENT TO INTERCALATION WITH BASE DISPLACEMENT
Descriptor:5'-D(*CP*CP*AP*TP*(5CM)P*(BPG)P*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3', 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE
Authors:Zhang, N., Lin, C., Huang, X., Kolbanovskiy, A., Hingerty, B.E., Amin, S., Broyde, S., Geacintov, N.E., Patel, D.J.
Deposit date:2004-12-15
Release date:2005-03-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement.
J.Mol.Biol., 346, 2005
1TN1
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CRYSTALLOGRAPHIC AND BIOCHEMICAL INVESTIGATION OF THE LEAD(II)-CATALYZED HYDROLYSIS OF YEAST PHENYLALANINE TRNA
Descriptor:TRNAPHE, SPERMINE, MAGNESIUM ION, ...
Authors:Dewan, J.C., Brown, R.S., Hingerty, B.E., Klug, A.
Deposit date:1986-12-04
Release date:1987-01-15
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA.
Biochemistry, 24, 1985
4TNA
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FURTHER REFINEMENT OF THE STRUCTURE OF YEAST T-RNA-PHE
Descriptor:TRNAPHE, MAGNESIUM ION
Authors:Hingerty, B.E., Brown, R.S., Jack, A.
Deposit date:1978-04-12
Release date:1978-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Further refinement of the structure of yeast tRNAPhe.
J.Mol.Biol., 124, 1978
1HZ0
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NMR STRUCTURE OF THE 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE (PHIP) C8-DEOXYGUANOSINE ADDUCT IN DUPLEX DNA
Descriptor:DNA (5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'), 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
Authors:Brown, K., Cosman, M.
Deposit date:2001-01-23
Release date:2001-08-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the 2-amino-1- methyl-6-phenylimidazo[4,5-b]pyridine C8-deoxyguanosine adduct in duplex DNA.
Proc.Natl.Acad.Sci.USA, 98, 2001
1TN2
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CRYSTALLOGRAPHIC AND BIOCHEMICAL INVESTIGATION OF THE LEAD(II)-CATALYZED HYDROLYSIS OF YEAST PHENYLALANINE T-RNA
Descriptor:TRNAPHE, SPERMINE, MAGNESIUM ION, ...
Authors:Brown, R.S., Dewan, J.C., Klug, A.
Deposit date:1986-08-22
Release date:1986-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA.
Biochemistry, 24, 1985