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1KTZ
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BU of 1ktz by Molmil
Crystal Structure of the Human TGF-beta Type II Receptor Extracellular Domain in Complex with TGF-beta3
Descriptor: TGF-beta Type II Receptor, TRANSFORMING GROWTH FACTOR BETA 3
Authors:Hart, P.J, Deep, S, Taylor, A.B, Shu, Z, Hinck, C.S, Hinck, A.P.
Deposit date:2002-01-18
Release date:2002-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex.
Nat.Struct.Biol., 9, 2002
6I9J
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BU of 6i9j by Molmil
Human transforming growth factor beta2 in a tetragonal crystal form
Descriptor: Transforming growth factor beta-2 proprotein
Authors:Gomis-Ruth, F.X, Marino-Puertas, L, del Amo-Maestro, L, Goulas, T.
Deposit date:2018-11-23
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor beta 2 in a new conformation.
Sci Rep, 9, 2019
7SXB
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BU of 7sxb by Molmil
NMR Solution Structure for Domain 3 of Heligmosomoides polygyrus protein Transforming Growth Factor Beta Mimic 1 (TGM-1 D3)
Descriptor: Transforming growth factor mimic
Authors:Mukundan, A, Byeon, C, Hinck, A.P.
Deposit date:2021-11-22
Release date:2022-05-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-beta to its receptors, T beta RI and T beta RII.
J.Biol.Chem., 298, 2022
6MZP
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BU of 6mzp by Molmil
Zebrafish betaglycan orphan domain structure from orthorhombic crystal form
Descriptor: Transforming growth factor beta receptor III
Authors:Hinck, A.P, Kim, S.
Deposit date:2018-11-05
Release date:2019-08-21
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Adaptation in Its Orphan Domain Engenders Betaglycan with an Alternate Mode of Growth Factor Binding Relative to Endoglin.
Structure, 27, 2019
6MZN
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BU of 6mzn by Molmil
Zebrafish betaglycan orphan domain structure from tetragonal crystal form
Descriptor: Transforming growth factor beta receptor III
Authors:Hinck, A.P, Kim, S.
Deposit date:2018-11-05
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural Adaptation in Its Orphan Domain Engenders Betaglycan with an Alternate Mode of Growth Factor Binding Relative to Endoglin.
Structure, 27, 2019
2L5S
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BU of 2l5s by Molmil
Solution structure of the extracellular domain of the TGF-beta type I receptor
Descriptor: TGF-beta receptor type-1
Authors:Zuniga, J.E, Ilangovan, U, Pardeep, M, Hinck, C, Huang, T.
Deposit date:2010-11-04
Release date:2011-10-26
Method:SOLUTION NMR
Cite:The TbetaR-I Pre-Helix Extension Is Structurally Ordered in the Unbound Form and Its Flanking Prolines Are Essential for Binding
J.Mol.Biol., 412, 2011
2JQE
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BU of 2jqe by Molmil
Soution Structure of Af54 M-domain
Descriptor: Signal recognition 54 kDa protein
Authors:Ilangovan, U, Hinck, A.P, Zwieb, C.
Deposit date:2007-05-31
Release date:2008-06-10
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:A. fulgidus SRP54 M-domain
J.Biomol.Nmr, 41, 2008
6MAC
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BU of 6mac by Molmil
Ternary structure of GDF11 bound to ActRIIB-ECD and Alk5-ECD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B, Growth/differentiation factor 11, ...
Authors:Goebel, E.J, Thompson, T.B.
Deposit date:2018-08-27
Release date:2019-07-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity.
Proc.Natl.Acad.Sci.USA, 116, 2019
5K7P
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BU of 5k7p by Molmil
MicroED structure of xylanase at 2.3 A resolution
Descriptor: Endo-1,4-beta-xylanase 2, IODIDE ION
Authors:de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2024-02-28
Method:ELECTRON CRYSTALLOGRAPHY (2.3 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7R
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BU of 5k7r by Molmil
MicroED structure of trypsin at 1.7 A resolution
Descriptor: CALCIUM ION, Cationic trypsin
Authors:de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2018-08-22
Method:ELECTRON CRYSTALLOGRAPHY (1.7 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5TX4
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BU of 5tx4 by Molmil
Derivative of mouse TGF-beta2, with a deletion of residues 52-71 and K25R, R26K, L51R, A74K, C77S, L89V, I92V, K94R T95K, I98V single amino acid substitutions, bound to human TGF-beta type II receptor ectodomain residues 15-130
Descriptor: TGF-beta receptor type-2, Transforming growth factor beta-2
Authors:Hinck, A.P, Kim, S.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.876 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5TX6
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BU of 5tx6 by Molmil
Structure of TGF-beta2 derivative with deletion of residues 52-71 and 10 single amino acid mutations (mmTGF-beta2-7M)
Descriptor: CALCIUM ION, Transforming growth factor beta-2
Authors:Petrunak, E.M, Hinck, A.P.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.746 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5TX2
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BU of 5tx2 by Molmil
Miniature TGF-beta2 3-mutant monomer
Descriptor: Transforming growth factor beta-2
Authors:Taylor, A.B, Kim, S.K, Hart, P.J, Hinck, A.P.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5K7Q
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BU of 5k7q by Molmil
MicroED structure of thaumatin at 2.5 A resolution
Descriptor: Thaumatin-1
Authors:de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2018-08-22
Method:ELECTRON CRYSTALLOGRAPHY (2.5 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7T
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BU of 5k7t by Molmil
MicroED structure of thermolysin at 2.5 A resolution
Descriptor: CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ...
Authors:de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2024-02-28
Method:ELECTRON CRYSTALLOGRAPHY (2.5 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7O
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BU of 5k7o by Molmil
MicroED structure of lysozyme at 1.8 A resolution
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2018-08-22
Method:ELECTRON CRYSTALLOGRAPHY (1.8 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7N
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BU of 5k7n by Molmil
MicroED structure of tau VQIVYK peptide at 1.1 A resolution
Descriptor: VQIVYK
Authors:de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2024-02-28
Method:ELECTRON CRYSTALLOGRAPHY (1.1 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7S
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BU of 5k7s by Molmil
MicroED structure of proteinase K at 1.6 A resolution
Descriptor: CALCIUM ION, Proteinase K
Authors:de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T.
Deposit date:2016-05-26
Release date:2017-04-05
Last modified:2018-08-22
Method:ELECTRON CRYSTALLOGRAPHY (1.6 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5TY4
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BU of 5ty4 by Molmil
MicroED structure of a complex between monomeric TGF-b and its receptor, TbRII, at 2.9 A resolution
Descriptor: TGF-beta receptor type-2, mmTGF-b2-7m
Authors:Weiss, S.C, de la Cruz, M.J, Hattne, J, Shi, D, Reyes, F.E, Callero, G, Gonen, T.
Deposit date:2016-11-18
Release date:2017-04-26
Last modified:2023-10-04
Method:ELECTRON CRYSTALLOGRAPHY (2.9 Å)
Cite:Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
2PJY
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BU of 2pjy by Molmil
Structural basis for cooperative assembly of the TGF-beta signaling complex
Descriptor: TGF-beta receptor type-1, TGF-beta receptor type-2, Transforming growth factor beta-3
Authors:Groppe, J, Zubieta, C.
Deposit date:2007-04-16
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding.
Mol.Cell, 29, 2008

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