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3MX0
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BU of 3mx0 by Molmil
Crystal Structure of EphA2 ectodomain in complex with ephrin-A5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 2, ...
Authors:Himanen, J.P, Yermekbayeva, L, Janes, P.W, Walker, J.R, Xu, K, Atapattu, L, Rajashankar, K.R, Mensinga, A, Lackmann, M, Nikolov, D.B, Dhe-Paganon, S.
Deposit date:2010-05-06
Release date:2010-06-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.506 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
1KGY
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BU of 1kgy by Molmil
Crystal Structure of the EphB2-ephrinB2 complex
Descriptor: EPHRIN TYPE-B RECEPTOR 2, EPHRIN-B2
Authors:Himanen, J.P, Rajashankar, K.R, Lackmann, M, Cowan, C.A, Henkemeyer, M, Nikolov, D.B.
Deposit date:2001-11-28
Release date:2002-05-28
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of an Eph receptor-ephrin complex.
Nature, 414, 2001
3HEI
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BU of 3hei by Molmil
Ligand Recognition by A-Class Eph Receptors: Crystal Structures of the EphA2 Ligand-Binding Domain and the EphA2/ephrin-A1 Complex
Descriptor: Ephrin type-A receptor 2, Ephrin-A1
Authors:Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B.
Deposit date:2009-05-08
Release date:2009-06-30
Last modified:2021-03-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.
Embo Rep., 10, 2009
3HPN
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BU of 3hpn by Molmil
Ligand recognition by A-class EPH receptors: crystal structures of the EPHA2 ligand-binding domain and the EPHA2/EPHRIN-A1 complex
Descriptor: Ephrin type-A receptor 2
Authors:Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B.
Deposit date:2009-06-04
Release date:2009-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.
Embo Rep., 10, 2009
1SHW
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BU of 1shw by Molmil
EphB2 / EphrinA5 Complex Structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, Ephrin-A5, ...
Authors:Himanen, J.P, Chumley, M.J, Lackmann, M, Li, C, Barton, W.A, Jeffrey, P.D, Vearing, C, Geleick, D, Feldheim, D.A, Boyd, A.W.
Deposit date:2004-02-26
Release date:2004-05-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
Nat.Neurosci., 7, 2004
1SHX
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BU of 1shx by Molmil
Ephrin A5 ligand structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin-A5
Authors:Himanen, J.P, Barton, W.A, Nikolov, D.B, Jeffrey, P.D.
Deposit date:2004-02-26
Release date:2005-04-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3.
J.Biol.Chem., 280, 2005
3ETP
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BU of 3etp by Molmil
The crystal structure of the ligand-binding domain of the EphB2 receptor at 2.0 A resolution
Descriptor: Ephrin type-B receptor 2
Authors:Goldgur, Y, Paavilainen, S, Nikolov, D.B, Himanen, J.P.
Deposit date:2008-10-08
Release date:2008-10-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the ligand-binding domain of the EphB2 receptor at 2 A resolution.
Acta Crystallogr.,Sect.F, 65, 2009
4M4R
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BU of 4m4r by Molmil
Epha4 ectodomain complex with ephrin a5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 4, ...
Authors:Xu, K, Tsvetkova-Robev, D, Xu, Y, Goldgur, Y, Chan, Y.-P, Himanen, J.P, Nikolov, D.B.
Deposit date:2013-08-07
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc.Natl.Acad.Sci.USA, 110, 2013
4M4P
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BU of 4m4p by Molmil
Crystal structure of EPHA4 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 4
Authors:Xu, K, Tsvetkova-Robev, D, Xu, Y, Goldgur, Y, Chan, Y.-P, Himanen, J.P, Nikolov, D.B.
Deposit date:2013-08-07
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.081 Å)
Cite:Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc.Natl.Acad.Sci.USA, 110, 2013
4P8S
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BU of 4p8s by Molmil
Crystal structure of Nogo-receptor-2
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Semavina, M, Saha, N, Kolev, M.V, Giger, R.J, Himanen, J.P, Nikolov, D.B.
Deposit date:2014-04-01
Release date:2014-04-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Nogo-receptor-2.
Protein Sci., 2011
1NUK
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BU of 1nuk by Molmil
CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE EPHB2 RECEPTOR TYROSINE KINASE
Descriptor: PROTEIN (TYROSINE-PROTEIN KINASE RECEPTOR EPH)
Authors:Himanen, J.-P, Henkemeyer, M, Nikolov, D.B.
Deposit date:1998-10-13
Release date:1999-10-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the ligand-binding domain of the receptor tyrosine kinase EphB2.
Nature, 396, 1998
3FL7
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BU of 3fl7 by Molmil
Crystal structure of the human ephrin A2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ephrin receptor, ...
Authors:Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2008-12-18
Release date:2009-01-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MBW
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BU of 3mbw by Molmil
Crystal structure of the human ephrin A2 LBD and CRD domains in complex with ephrin A1
Descriptor: Ephrin type-A receptor 2, Ephrin-A1, UNKNOWN ATOM OR ION, ...
Authors:Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2010-03-26
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3C8X
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BU of 3c8x by Molmil
Crystal structure of the ligand binding domain of human Ephrin A2 (Epha2) receptor protein kinase
Descriptor: Ephrin type-A receptor 2
Authors:Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2008-02-14
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3CZU
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BU of 3czu by Molmil
Crystal structure of the human ephrin A2- ephrin A1 complex
Descriptor: Ephrin type-A receptor 2, Ephrin-A1, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Wikstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2008-04-30
Release date:2008-08-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
7K7J
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BU of 7k7j by Molmil
EphB6 receptor ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 6
Authors:Goldgur, Y, Himanen, J.
Deposit date:2020-09-22
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:Structure of the EphB6 receptor ectodomain.
Plos One, 16, 2021
7S7K
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BU of 7s7k by Molmil
Crystal structure of the EphB2 extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, ...
Authors:Xu, Y, Xu, K, Nikolov, D.B.
Deposit date:2021-09-16
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism.
Int J Mol Sci, 22, 2021
2OQX
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BU of 2oqx by Molmil
Crystal Structure of the apo form of E. coli tryptophanase at 1.9 A resolution
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Goldgur, Y, Kogan, A, Gdalevsky, G, Parola, A, Cohen-Luria, R, Almog, O.
Deposit date:2007-02-01
Release date:2007-02-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of apo tryptophanase from Escherichia coli reveals a wide-open conformation.
Acta Crystallogr.,Sect.D, 63, 2007
3D11
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BU of 3d11 by Molmil
Crystal Structures of the Nipah G Attachment Glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-neuraminidase, ...
Authors:Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B.
Deposit date:2008-05-02
Release date:2008-08-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3.
Proc.Natl.Acad.Sci.USA, 105, 2008
3D12
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BU of 3d12 by Molmil
Crystal Structures of Nipah Virus G Attachment Glycoprotein in Complex with its Receptor Ephrin-B3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin-B3, ...
Authors:Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B.
Deposit date:2008-05-02
Release date:2008-08-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3.
Proc.Natl.Acad.Sci.USA, 105, 2008
2GY5
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BU of 2gy5 by Molmil
Tie2 Ligand-Binding Domain Crystal Structure
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiopoietin-1 receptor, ...
Authors:Barton, W.A, Nikolov, D.B.
Deposit date:2006-05-09
Release date:2006-06-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex.
Nat.Struct.Mol.Biol., 13, 2006
2GY7
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BU of 2gy7 by Molmil
Angiopoietin-2/Tie2 Complex Crystal Structure
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barton, W.A, Nikolov, D.B.
Deposit date:2006-05-09
Release date:2006-06-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex.
Nat.Struct.Mol.Biol., 13, 2006
4P91
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BU of 4p91 by Molmil
Crystal structure of the nogo-receptor-2 (27-330)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Reticulon-4 receptor-like 2
Authors:Semavina, M, Saha, N, Kolev, M, Goldgur, Y, Giger, R, Himanen, J, Nikolov, D.
Deposit date:2014-04-01
Release date:2014-04-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the Nogo-receptor-2.
Protein Sci., 20, 2011
3GXU
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BU of 3gxu by Molmil
Crystal structure of Eph receptor and ephrin complex
Descriptor: Ephrin type-A receptor 4, Ephrin-B2
Authors:Qin, H.N, Song, J.X.
Deposit date:2009-04-03
Release date:2009-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterization of the EphA4-ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity
J.Biol.Chem., 2009

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