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3DQB
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CRYSTAL STRUCTURE OF THE ACTIVE G-PROTEIN-COUPLED RECEPTOR OPSIN IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM THE GALPHA SUBUNIT OF TRANSDUCIN
Descriptor:Rhodopsin, 11meric peptide form Guanine nucleotide-binding protein G(t) subunit alpha-1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Scheerer, P., Park, J.H., Hildebrand, P.W., Kim, Y.J., Krauss, N., Choe, H.-W., Hofmann, K.P., Ernst, O.P.
Deposit date:2008-07-09
Release date:2008-09-23
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of opsin in its G-protein-interacting conformation
Nature, 455, 2008
3JCJ
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STRUCTURES OF RIBOSOME-BOUND INITIATION FACTOR 2 REVEAL THE MECHANISM OF SUBUNIT ASSOCIATION
Descriptor:5S ribosomal RNA, 30S ribosomal protein S18, 30S ribosomal protein S21, ...
Authors:Sprink, T., Ramrath, D.J.F., Yamamoto, H., Yamamoto, K., Loerke, J., Ismer, J., Hildebrand, P.W., Scheerer, P., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2015-12-18
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
3JCN
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STRUCTURES OF RIBOSOME-BOUND INITIATION FACTOR 2 REVEAL THE MECHANISM OF SUBUNIT ASSOCIATION: INITIATION COMPLEX I
Descriptor:50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, ...
Authors:Sprink, T., Ramrath, D.J.F., Yamamoto, H., Yamamoto, K., Loerke, J., Ismer, J., Hildebrand, P.W., Scheerer, P., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2016-01-04
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
4V5M
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TRNA TRANLOCATION ON THE 70S RIBOSOME: THE PRE-TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(PRE)
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T.
Deposit date:2010-10-01
Release date:2014-07-09
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
4V5N
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TRNA TRANSLOCATION ON THE 70S RIBOSOME: THE POST- TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(POST)
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T.
Deposit date:2010-10-21
Release date:2014-07-09
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
5FLX
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MAMMALIAN 40S HCV-IRES COMPLEX
Descriptor:18S RRNA, 40S RIBOSOMAL PROTEIN SA, 40S RIBOSOMAL PROTEIN S3A, ...
Authors:Yamamoto, H., Collier, M., Loerke, J., Ismer, J., Schmidt, A., Hilal, T., Sprink, T., Yamamoto, K., Mielke, T., Burger, J., Shaikh, T.R., Dabrowski, M., Hildebrand, P.W., Scheerer, P., Spahn, C.M.T.
Deposit date:2015-10-28
Release date:2015-12-23
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA.
Embo J., 34, 2015
4CXG
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:18S RRNA - H44, 28S RRNA - H89, ELONGATION FACTOR 1A, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-07
Release date:2014-07-16
Last modified:2019-06-26
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
4CXH
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:18S RRNA - H44, 28S RRNA - H89, ELONGATION FACTOR 1A, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-07
Release date:2014-07-16
Last modified:2019-06-26
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
4UJE
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:TRNA-LYS, TRNA-PHE, Messenger RNA, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-05
Release date:2014-07-16
Last modified:2019-06-26
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
6E67
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STRUCTURE OF BETA2 ADRENERGIC RECEPTOR FUSED TO A GS PEPTIDE
Descriptor:Beta-2 adrenergic receptor,Endolysin,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Beta-2 adrenergic receptor chimera, 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one
Authors:Liu, X., Xu, X., Hilger, D., Tiemann, J., Liu, H., Du, Y., Hirata, K., Sun, X., Guixa-Gonzalez, R., Mathiesen, J., Hildebrand, P., Kobilka, B.
Deposit date:2018-07-24
Release date:2019-06-05
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural Insights into the Process of GPCR-G Protein Complex Formation.
Cell, 177, 2019
4PXF
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CRYSTAL STRUCTURE OF THE ACTIVE G-PROTEIN-COUPLED RECEPTOR OPSIN IN COMPLEX WITH THE FINGER-LOOP PEPTIDE DERIVED FROM THE FULL-LENGTH ARRESTIN-1
Descriptor:Rhodopsin, S-arrestin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Szczepek, M., Scheerer, P.
Deposit date:2014-03-23
Release date:2014-09-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of a common GPCR-binding interface for G protein and arrestin.
Nat Commun, 5, 2014
6EG8
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STRUCTURE OF THE GDP-BOUND GS HETEROTRIMER
Descriptor:Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Hilger, D., Liu, X., Aschauer, P., Kobilka, B.K.
Deposit date:2018-08-19
Release date:2019-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights into the Process of GPCR-G Protein Complex Formation.
Cell, 177, 2019