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2QXG
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CRYSTAL STRUCTURE OF HUMAN KALLIKREIN 7 IN COMPLEX WITH ALA-ALA-PHE-CHLOROMETHYLKETONE
Descriptor:Kallikrein-7, L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide
Authors:Debela, M., Hess, P., Magdolen, V., Bode, W., Steiner, T., Goettig, P.
Deposit date:2007-08-11
Release date:2008-01-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QXH
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CRYSTAL STRUCTURE OF HUMAN KALLIKREIN 7 IN COMPLEX WITH SUC-ALA-ALA-PRO-PHE-CHLOROMETHYLKETONE
Descriptor:Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide
Authors:Debela, M., Hess, P., Magdolen, V., Schechter, N.M., Bode, W., Goettig, P.
Deposit date:2007-08-11
Release date:2008-01-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QXI
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HIGH RESOLUTION STRUCTURE OF HUMAN KALLIKREIN 7 IN COMPLEX WITH SUC-ALA-ALA-PRO-PHE-CHLOROMETHYLKETONE
Descriptor:Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide
Authors:Debela, M., Hess, P., Magdolen, V., Schechter, N.M., Bode, W., Goettig, P.
Deposit date:2007-08-11
Release date:2008-01-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1 Å)
Cite:Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QXJ
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CRYSTAL STRUCTURE OF HUMAN KALLIKREIN 7 IN COMPLEX WITH SUC-ALA-ALA-PRO-PHE-CHLOROMETHYLKETONE AND COPPER
Descriptor:Kallikrein-7, COPPER (II) ION, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide
Authors:Debela, M., Hess, P., Magdolen, V., Schechter, N.M., Bode, W., Goettig, P.
Deposit date:2007-08-11
Release date:2008-01-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3O9L
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DESIGN AND OPTIMISATION OF NEW PIPERIDINES AS RENIN INHIBITORS
Descriptor:Renin, N-ACETYL-D-GLUCOSAMINE, (3R,4S)-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropyl-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-3-carboxamide
Authors:Corminboeuf, O., Bezencon, O., Grisostomi, C., Remen, L., Richard-Bildstein, S., Bur, D., Prade, L., Hess, P., Strickner, P., Treiber, A.
Deposit date:2010-08-04
Release date:2011-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Design and optimization of new piperidines as renin inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
2Q6P
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THE CHEMICAL CONTROL OF PROTEIN FOLDING: ENGINEERING A SUPERFOLDER GREEN FLUORESCENT PROTEIN
Descriptor:Green fluorescent protein mutant 3
Authors:Steiner, T., Hess, P., Bae, J.H., Wiltschi, B., Moroder, L., Budisa, N.
Deposit date:2007-06-05
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Synthetic biology of proteins: tuning GFPs folding and stability with fluoroproline.
Plos One, 3, 2008
3G6Z
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DESIGN AND PREPARATION OF POTENT, NON-PEPTIDIC, BIOAVAILABLE RENIN INHIBITORS
Descriptor:Renin, (1R,5S)-N-cyclopropyl-7-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}-N-(2,3-dimethylbenzyl)-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Bezencon, O., Bur, D., Prade, L., Weller, T., Boss, C., Fischli, W.
Deposit date:2009-02-09
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Preparation of Potent, Nonpeptidic, Bioavailable Renin Inhibitors
J.Med.Chem., 52, 2009
3G70
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DESIGN AND PREPARATION OF POTENT, NON-PEPTIDIC, BIOAVAILABLE RENIN INHIBITORS
Descriptor:Renin, (1R,5S)-7-{4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl}-N-cyclopropyl-N-(2,3-dichlorobenzyl)-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide, DIMETHYL SULFOXIDE, ...
Authors:Bezencon, O., Bur, D., Prade, L., Weller, T., Boss, C., Fischli, W.
Deposit date:2009-02-09
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Preparation of Potent, Nonpeptidic, Bioavailable Renin Inhibitors
J.Med.Chem., 52, 2009
3G72
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DESIGN AND PREPARATION OF POTENT, NON-PEPTIDIC, BIOAVAILABLE RENIN INHIBITORS
Descriptor:Renin, DIMETHYL SULFOXIDE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Bezencon, O., Bur, D., Prade, L., Weller, T., Boss, C., Fischli, W.
Deposit date:2009-02-09
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design and Preparation of Potent, Nonpeptidic, Bioavailable Renin Inhibitors
J.Med.Chem., 52, 2009
3K1W
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NEW CLASSES OF POTENT AND BIOAVAILABLE HUMAN RENIN INHIBITORS
Descriptor:Renin, 4-{4-[3-(2-bromo-5-fluorophenoxy)propyl]phenyl}-N-(2-chlorobenzyl)-N-cyclopropyl-1,2,5,6-tetrahydropyridine-3-carboxamide, FORMIC ACID, ...
Authors:Prade, L.
Deposit date:2009-09-29
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:New classes of potent and bioavailable human renin inhibitors
Bioorg.Med.Chem.Lett., 19, 2009
3OAD
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DESIGN AND OPTIMIZATION OF NEW PIPERIDINES AS RENIN INHIBITORS
Descriptor:Renin, N-ACETYL-D-GLUCOSAMINE, (3S,4R)-N-[2-chloro-5-(2-methoxyethyl)benzyl]-N-cyclopropyl-4-{6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]pyridin-3-yl}-4-hydroxypiperidine-3-carboxamide
Authors:Prade, L.
Deposit date:2010-08-05
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Design and optimization of new piperidines as renin inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3OAG
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DESIGN AND OPTIMIZATION OF NEW PIPERIDINES AS RENIN INHIBITORS
Descriptor:Renin, N-ACETYL-D-GLUCOSAMINE, (3R,4S)-N-{2-chloro-5-[(cyclopropylamino)methyl]benzyl}-N-cyclopropyl-4-{6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]pyridin-3-yl}piperidine-3-carboxamide
Authors:Prade, L.
Deposit date:2010-08-05
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design and optimization of new piperidines as renin inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
2OEF
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OPEN AND CLOSED STRUCTURES OF THE UDP-GLUCOSE PYROPHOSPHORYLASE FROM LEISHMANIA MAJOR
Descriptor:UTP-glucose-1-phosphate uridylyltransferase 2, putative, SULFATE ION
Authors:Steiner, T.
Deposit date:2006-12-29
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Open and Closed Structures of the UDP-glucose Pyrophosphorylase from Leishmania major.
J.Biol.Chem., 282, 2007
2OEG
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OPEN AND CLOSED STRUCTURES OF THE UDP-GLUCOSE PYROPHOSPHORYLASE FROM LEISHMANIA MAJOR
Descriptor:UTP-glucose-1-phosphate uridylyltransferase 2, putative, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Steiner, T.
Deposit date:2006-12-29
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Open and Closed Structures of the UDP-glucose Pyrophosphorylase from Leishmania major.
J.Biol.Chem., 282, 2007