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1V57
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CRYSTAL STRUCTURE OF THE DISULFIDE BOND ISOMERASE DSBG
Descriptor:Thiol:disulfide interchange protein dsbG, SULFATE ION
Authors:Heras, B., Edeling, M.A., Schirra, H.J., Raina, S., Martin, J.L.
Deposit date:2003-11-21
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide
Proc.Natl.Acad.Sci.USA, 101, 2004
1V58
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CRYSTAL STRUCTURE OF THE REDUCED PROTEIN DISULFIDE BOND ISOMERASE DSBG
Descriptor:Thiol:disulfide interchange protein dsbG, SULFATE ION
Authors:Heras, B., Edeling, M.A., Schirra, H.J., Raina, S., Martin, J.L.
Deposit date:2003-11-21
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide
Proc.Natl.Acad.Sci.USA, 101, 2004
3BCI
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS DSBA
Descriptor:Disulfide bond protein A
Authors:Heras, B., Thony-Meyer, L., Martin, J.L.
Deposit date:2007-11-12
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Staphylococcus aureus DsbA Does Not Have a Destabilizing Disulfide: A NEW PARADIGM FOR BACTERIAL OXIDATIVE FOLDING
J.Biol.Chem., 283, 2008
3BCK
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS DSBA T153V
Descriptor:Disulfide bond protein A
Authors:Heras, B., Thony-Meyer, L., Martin, J.L.
Deposit date:2007-11-13
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Staphylococcus aureus DsbA Does Not Have a Destabilizing Disulfide: A NEW PARADIGM FOR BACTERIAL OXIDATIVE FOLDING
J.Biol.Chem., 283, 2008
3BD2
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS DSBA E96Q
Descriptor:Disulfide bond protein A
Authors:Heras, B., Thony-Meyer, L., Martin, J.L.
Deposit date:2007-11-13
Release date:2007-12-11
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Staphylococcus aureus DsbA Does Not Have a Destabilizing Disulfide: A NEW PARADIGM FOR BACTERIAL OXIDATIVE FOLDING
J.Biol.Chem., 283, 2008
3L9S
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CRYSTAL STRUCTURE OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM DSBA
Descriptor:Thiol:disulfide interchange protein
Authors:Heras, B., Jarrott, R., Shouldice, S.R., Guncar, G.
Deposit date:2010-01-05
Release date:2010-03-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium
J.Biol.Chem., 285, 2010
3L9U
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CRYSTAL STRUCTURE OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM DSBL
Descriptor:Disulfide isomerase
Authors:Heras, B., Jarrott, R., Shouldice, S.R., Guncar, G.
Deposit date:2010-01-05
Release date:2010-03-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.568 Å)
Cite:Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium
J.Biol.Chem., 285, 2010
3L9V
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CRYSTAL STRUCTURE OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM SRGA
Descriptor:Putative thiol-disulfide isomerase or thioredoxin, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, ...
Authors:Heras, B., Jarrott, R., Shouldice, S.R., Guncar, G.
Deposit date:2010-01-05
Release date:2010-03-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium
J.Biol.Chem., 285, 2010
4KH3
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STRUCTURE OF A BACTERIAL SELF-ASSOCIATING PROTEIN
Descriptor:Antigen 43, MALONATE ION
Authors:Heras, B., Gee, C.L., Schembri, M.A., Totsika, M.
Deposit date:2013-04-30
Release date:2014-01-15
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping.
Proc.Natl.Acad.Sci.USA, 111, 2014
6BQX
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI DSBA IN COMPLEX WITH N-METHYL-1-(4-PHENOXYPHENYL)METHANAMINE
Descriptor:Thiol:disulfide interchange protein DsbA, N-methyl-1-(4-phenoxyphenyl)methanamine
Authors:Heras, B., Totsika, M., Paxman, J.J., Wang, G., Scanlon, M.J.
Deposit date:2017-11-29
Release date:2017-12-27
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.992 Å)
Cite:Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens.
Antioxid. Redox Signal., 29, 2018
6BR4
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI DSBA IN COMPLEX WITH {N}-METHYL-1-(3-THIOPHEN-2-YLPHENYL)METHANAMINE
Descriptor:Thiol:disulfide interchange protein DsbA, ~{N}-methyl-1-(3-thiophen-2-ylphenyl)methanamine, COPPER (II) ION
Authors:Heras, B., Totsika, M., Paxman, J.J., Wang, G., Scanlon, M.J., Martin, J.L.
Deposit date:2017-11-29
Release date:2017-12-27
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens.
Antioxid. Redox Signal., 29, 2018
6DNU
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CRYSTAL STRUCTURE OF NEISSERIA MENINGITIDIS DSBD C-TERMINAL DOMAIN IN THE OXIDISED FORM
Descriptor:Thiol:disulfide interchange protein DsbD, HEXAETHYLENE GLYCOL
Authors:Heras, B., Smith, R.P., Paxman, J.J.
Deposit date:2018-06-07
Release date:2018-09-12
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2.283 Å)
Cite:Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens.
J. Biol. Chem., 293, 2018
6DPS
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CRYSTAL STRUCTURE OF NEISSERIA MENINGITIDIS DSBD N-TERMINAL DOMAIN IN THE OXIDISED FORM
Descriptor:Thiol:disulfide interchange protein DsbD, ZINC ION
Authors:Heras, B., Smith, R.P., Paxman, J.J.
Deposit date:2018-06-09
Release date:2018-09-12
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2.556 Å)
Cite:Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens.
J. Biol. Chem., 293, 2018
5EK5
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STRUCTURAL CHARACTERIZATION OF IRMA FROM ESCHERICHIA COLI
Descriptor:IRMA, CHLORIDE ION, FORMIC ACID, ...
Authors:Heras, B., Moriel, D.G., Paxman, J.J., Schembri, M.A.
Deposit date:2015-11-03
Release date:2016-03-09
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Molecular and Structural Characterization of a Novel Escherichia coli Interleukin Receptor Mimic Protein.
Mbio, 7, 2016
6DNL
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CRYSTAL STRUCTURE OF NEISSERIA MENINGITIDIS DSBD C-TERMINAL DOMAIN IN THE REDUCED FORM
Descriptor:Thiol:disulfide interchange protein DsbD, ZINC ION, ACETATE ION
Authors:Smith, R.P., Heras, B., Paxman, J.J.
Deposit date:2018-06-06
Release date:2018-09-12
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens.
J. Biol. Chem., 293, 2018
6DNV
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CRYSTAL STRUCTURE OF NEISSERIA MENINGITIDIS DSBD N-TERMINAL DOMAIN IN THE REDUCED FORM
Descriptor:Thiol:disulfide interchange protein DsbD, SULFATE ION
Authors:Smith, R.P., Heras, B., Paxman, J.J.
Deposit date:2018-06-08
Release date:2018-09-12
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens.
J. Biol. Chem., 293, 2018
2H0G
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CRYSTAL STRUCTURE OF DSBG T200M MUTANT
Descriptor:Thiol:disulfide interchange protein dsbG, SULFATE ION
Authors:Hiniker, A., Heras, B., Martin, J.L., Stuckey, J., Bardwell, J.C.A.
Deposit date:2006-05-15
Release date:2007-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Short-circuiting divergent evolution: laboratory evolution of one disulfide isomerase to resemble another
To be Published
2H0H
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CRYSTAL STRUCTURE OF DSBG K113E MUTANT
Descriptor:Thiol:disulfide interchange protein dsbG, SULFATE ION
Authors:Hiniker, A., Heras, B., Martin, J.L., Stuckey, J., Bardwell, J.C.A.
Deposit date:2006-05-15
Release date:2007-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Short-circuiting divergent evolution: laboratory evolution of one disulfide isomerase to resemble another
To be Published
2H0I
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CRYSTAL STRUCTURE OF DSBG V216M MUTANT
Descriptor:Thiol:disulfide interchange protein dsbG, SULFATE ION
Authors:Hiniker, A., Heras, B., Martin, J.L., Stuckey, J., Bardwell, J.C.A.
Deposit date:2006-05-15
Release date:2007-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Short-circuiting divergent evolution: laboratory evolution of one disulfide isomerase to resemble another
To be Published
3A3T
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THE OXIDOREDUCTASE NMDSBA1 FROM N. MENINGITIDIS
Descriptor:Thiol:disulfide interchange protein DsbA
Authors:Vivian, J.P., Scoullar, J., Bushell, S., Beddoe, T., Wilce, M.C.J., Byres, E., Boyle, T.P., Rimmer, K., Doak, B., Simpson, J.S., Graham, B., Heras, B., Kahler, C.M., Rossjohn, J., Scanlon, M.J.
Deposit date:2009-06-19
Release date:2009-10-20
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and function of the oxidoreductase DsbA1 from Neisseria meningitidis
J.Mol.Biol., 394, 2009
2MBS
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NMR SOLUTION STRUCTURE OF OXIDIZED KPDSBA
Descriptor:Thiol:disulfide interchange protein
Authors:Kurth, F., Rimmer, K., Premkumar, L., Mohanty, B., Duprez, W., Halili, M.A., Shouldice, S.R., Heras, B., Fairlie, D.P., Scanlon, M.J., Martin, J.L.
Deposit date:2013-08-03
Release date:2013-12-11
Method:SOLUTION NMR
Cite:Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes.
Plos One, 8, 2013
4WEY
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CRYSTAL STRUCTURE OF E.COLI DSBA IN COMPLEX WITH COMPOUND 17
Descriptor:Thiol:disulfide interchange protein, 1,2-ETHANEDIOL, N-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}carbonyl)-L-serine
Authors:Adams, L.A., Sharma, P., Mohanty, B., Ilyichova, O.V., Mulcair, M.D., Williams, M.L., Gleeson, E.C., Totsika, M., Doak, B.C., Caria, S., Rimmer, K., Shouldice, S.R., Vazirani, M., Headey, S.J., Plumb, B.R., Martin, J.L., Heras, B., Simpson, J.S., Scanlon, M.J.
Deposit date:2014-09-11
Release date:2015-01-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA.
Angew.Chem.Int.Ed.Engl., 54, 2015
4WF4
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CRYSTAL STRUCTURE OF E.COLI DSBA CO-CRYSTALLISED IN COMPLEX WITH COMPOUND 4
Descriptor:Thiol:disulfide interchange protein, 1,2-ETHANEDIOL, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid
Authors:Adams, L.A., Sharma, P., Mohanty, B., Ilyichova, O.V., Mulcair, M.D., Williams, M.L., Gleeson, E.C., Totsika, M., Doak, B.C., Caria, S., Rimmer, K., Shouldice, S.R., Vazirani, M., Headey, S.J., Plumb, B.R., Martin, J.L., Heras, B., Simpson, J.S., Scanlon, M.J.
Deposit date:2014-09-12
Release date:2015-01-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA.
Angew.Chem.Int.Ed.Engl., 54, 2015
4WF5
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CRYSTAL STRUCTURE OF E.COLI DSBA SOAKED WITH COMPOUND 4
Descriptor:Thiol:disulfide interchange protein, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid, COPPER (II) ION, ...
Authors:Adams, L.A., Sharma, P., Mohanty, B., Ilyichova, O.V., Mulcair, M.D., Williams, M.L., Gleeson, E.C., Totsika, M., Doak, B.C., Caria, S., Rimmer, K., Shouldice, S.R., Vazirani, M., Headey, S.J., Plumb, B.R., Martin, J.L., Heras, B., Simpson, J.S., Scanlon, M.J.
Deposit date:2014-09-12
Release date:2015-01-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA.
Angew.Chem.Int.Ed.Engl., 54, 2015
3F4R
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CRYSTAL STRUCTURE OF WOLBACHIA PIPIENTIS ALPHA-DSBA1
Descriptor:Putative uncharacterized protein, TRIETHYLENE GLYCOL, PENTAETHYLENE GLYCOL
Authors:Kurz, M., Heras, B., Martin, J.L.
Deposit date:2008-11-02
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Functional Characterization of the Oxidoreductase alpha-DsbA1 from Wolbachia pipientis
ANTIOXID.REDOX SIGNAL., 11, 2009
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