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6TRT
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BU of 6trt by Molmil
Chaetomium thermophilum UDP-Glucose Glucosyl Transferase (UGGT) double cysteine mutant S180C/T742C.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, TERBIUM(III) ION, UDP-glucose-glycoprotein glucosyltransferase-like protein, ...
Authors:Roversi, P, Zitzmann, N, Ibba, R, Hensen, M.
Deposit date:2019-12-19
Release date:2020-01-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (4.58 Å)
Cite:Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase.
Structure, 29, 2021
6TS8
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BU of 6ts8 by Molmil
Chaetomium thermophilum UDP-Glucose Glucosyl Transferase (UGGT) double cysteine mutant G177C/A786C.
Descriptor: UDP-glucose-glycoprotein glucosyltransferase-like protein
Authors:Roversi, P, Zitzmann, N, Ibba, R, Hensen, M, Chandran, A.
Deposit date:2019-12-20
Release date:2020-10-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase.
Structure, 29, 2021
7ZLL
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BU of 7zll by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with the 5-[(morpholin-4-yl)methyl]quinolin-8-ol inhibitor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-(morpholin-4-ylmethyl)quinolin-8-ol, UDP-glucose-glycoprotein glucosyltransferase-like protein, ...
Authors:Roversi, P, Zitzmann, N, Bayo, Y, Kantsadi, A.L, Chandran, A.V.
Deposit date:2022-04-15
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.
Iscience, 26, 2023
7ZXW
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BU of 7zxw by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with the 5-[(morpholin-4-yl)methyl]quinolin-8-ol inhibitor
Descriptor: 5-(morpholin-4-ylmethyl)quinolin-8-ol, CALCIUM ION, DIMETHYL SULFOXIDE, ...
Authors:Le Cornu, J.D, Ibba, R, Roversi, P, Zitzmann, N.
Deposit date:2022-05-23
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.246 Å)
Cite:Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint.
Front Mol Biosci, 9, 2022
6FSN
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BU of 6fsn by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 1)
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Roversi, P, Le Cornu, J.D, Hill, J, Alonzi, D.S, Zitzmann, N.
Deposit date:2018-02-19
Release date:2019-03-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint.
Front Mol Biosci, 2022
7QPD
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BU of 7qpd by Molmil
Structure of the human MHC I peptide-loading complex editing module
Descriptor: Beta-2-microglobulin, Calreticulin, HLA class I histocompatibility antigen, ...
Authors:Domnick, A, Susac, L, Trowitzsch, S, Thomas, C, Tampe, R.
Deposit date:2022-01-03
Release date:2022-07-20
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Molecular basis of MHC I quality control in the peptide loading complex.
Nat Commun, 13, 2022
7ZKC
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BU of 7zkc by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (apo form)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, UDP-glucose-glycoprotein glucosyltransferase-like protein
Authors:Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D.
Deposit date:2022-04-12
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.769 Å)
Cite:A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.
Iscience, 26, 2023
7ZLU
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BU of 7zlu by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-2-deoxy-2-fluoro-D-glucose
Descriptor: 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Roversi, P, Zitzmann, N, Bayo, Y, Ibba, R.
Deposit date:2022-04-15
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.
Iscience, 26, 2023
6TRF
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BU of 6trf by Molmil
Chaetomium thermophilum UDP-Glucose Glucosyl Transferase (UGGT) purified from cells treated with kifunensine.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, UDP-glucose-glycoprotein glucosyltransferase-like protein, ...
Authors:Roversi, P, Zitzmann, N.
Deposit date:2019-12-18
Release date:2020-01-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (4.106 Å)
Cite:Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase.
Structure, 29, 2021
6TS2
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BU of 6ts2 by Molmil
Truncated version of Chaetomium thermophilum UDP-Glucose Glucosyl Transferase (UGGT) lacking domain TRXL2 (417-650).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein, ...
Authors:Roversi, P, Zitzmann, N.
Deposit date:2019-12-19
Release date:2020-01-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (5.74 Å)
Cite:Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase.
Structure, 29, 2021
7ZHB
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BU of 7zhb by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 2)
Descriptor: 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D.
Deposit date:2022-04-06
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
To Be Published
7ZLE
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BU of 7zle by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP
Descriptor: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D.
Deposit date:2022-04-14
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.823 Å)
Cite:A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
To Be Published

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PDB entries from 2024-03-27

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