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4O9H
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BU of 4o9h by Molmil
Structure of Interleukin-6 in complex with a Camelid Fab fragment
Descriptor: Heavy Chain of the Camelid Fab fragment 61H7, Interleukin-6, Light Chain of the Camelid Fab fragment 61H7
Authors:Klarenbeek, A, Blanchetot, C, Schragel, G, Sadi, A.S, Ongenae, N, Hemrika, W, Wijdenes, J, Spinelli, S, Desmyter, A, Cambillau, C, Hultberg, A, Kretz-rommel, A, Dreier, T, De haard, H.J.W, Roovers, R.C.
Deposit date:2014-01-02
Release date:2015-04-15
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Combining residues of naturally-occurring Camelid somatic affinity variants yields ultra-potent human therapeutic IL-6 antibodies
To be Published
2WFH
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BU of 2wfh by Molmil
The Human Slit 2 Dimerization Domain D4
Descriptor: SLIT HOMOLOG 2 PROTEIN C-PRODUCT, SULFATE ION
Authors:Seiradake, E, von Philipsborn, A.C, Henry, M, Fritz, M, Lortat-Jacob, H, Jamin, M, Hemrika, W, Bastmeyer, M, Cusack, S, McCarthy, A.A.
Deposit date:2009-04-06
Release date:2009-04-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and functional relevance of the Slit2 homodimerization domain.
EMBO Rep., 10, 2009
2I6S
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BU of 2i6s by Molmil
Complement component C2a
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C2a fragment, ...
Authors:Milder, F.J, Raaijmakers, H.C.A, Vandeputte, D.A.A, Schouten, A, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P.
Deposit date:2006-08-29
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of complement component c2a: implications for convertase formation and substrate binding.
Structure, 14, 2006
2I6Q
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BU of 2i6q by Molmil
Complement component C2a
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C2a fragment, ...
Authors:Milder, F.J, Raaijmakers, H.C.A, Vandeputte, D.A.A, Schouten, A, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P.
Deposit date:2006-08-29
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of complement component c2a: implications for convertase formation and substrate binding.
Structure, 14, 2006
2OK5
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BU of 2ok5 by Molmil
Human Complement factor B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement factor B, ...
Authors:Milder, F.J, Gomes, L, Schouten, A, Janssen, B.J.C, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P.
Deposit date:2007-01-16
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Factor B structure provides insights into activation of the central protease of the complement system.
Nat.Struct.Mol.Biol., 14, 2007
2V9T
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BU of 2v9t by Molmil
Complex between the second LRR domain of Slit2 and The first Ig domain from Robo1
Descriptor: ROUNDABOUT HOMOLOG 1, SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Authors:Morlot, C, Cusack, S, McCarthy, A.A.
Deposit date:2007-08-25
Release date:2007-09-25
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V9Q
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BU of 2v9q by Molmil
First and second Ig domains from human Robo1
Descriptor: MERCURY (II) ION, ROUNDABOUT HOMOLOG 1
Authors:Morlot, C, Cusack, S, McCarthy, A.A.
Deposit date:2007-08-25
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V9S
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BU of 2v9s by Molmil
Second LRR domain of human Slit2
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Authors:Morlot, C, Cusack, S, McCarthy, A.A.
Deposit date:2007-08-25
Release date:2007-09-25
Last modified:2014-11-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V9R
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BU of 2v9r by Molmil
First and second Ig domains from human Robo1 (Form 2)
Descriptor: ROUNDABOUT HOMOLOG 1, SULFATE ION
Authors:Morlot, C, Cusack, S, McCarthy, A.A.
Deposit date:2007-08-25
Release date:2007-09-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
3D68
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BU of 3d68 by Molmil
Crystal structure of a T325I/T329I/H333Y/H335Q mutant of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI-IIYQ)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ARGININE, Carboxypeptidase B2, ...
Authors:Brondijk, T.H.C, Huizinga, E.G.
Deposit date:2008-05-19
Release date:2008-07-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
3D66
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BU of 3d66 by Molmil
Crystal structure of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase B2, ZINC ION
Authors:Brondijk, T.H.C, Huizinga, E.G.
Deposit date:2008-05-19
Release date:2008-07-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
3D67
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BU of 3d67 by Molmil
Crystal structure of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) in complex with 2-guanidino-ethyl-mercaptosuccinic acid (GEMSA)
Descriptor: (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase B2, ...
Authors:Brondijk, T.H.C, Huizinga, E.G.
Deposit date:2008-05-19
Release date:2008-07-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
1VNE
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BU of 1vne by Molmil
CHLOROPEROXIDASE FROM THE FUNGUS CURVULARIA INAEQUALIS: MUTANT D292A
Descriptor: VANADATE ION, VANADIUM CHLOROPEROXIDASE
Authors:Macedo-Ribeiro, S, Messerschmidt, A.
Deposit date:1999-01-20
Release date:1999-08-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
1VNF
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BU of 1vnf by Molmil
CHLOROPEROXIDASE FROM THE FUNGUS CURVULARIA INAEQUALIS: MUTANT R360A
Descriptor: VANADATE ION, VANADIUM CHLOROPEROXIDASE
Authors:Macedo-Ribeiro, S, Messerschmidt, A.
Deposit date:1999-01-20
Release date:1999-08-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
1VNG
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BU of 1vng by Molmil
CHLOROPEROXIDASE FROM THE FUNGUS CURVULARIA INAEQUALIS: MUTANT H404A
Descriptor: VANADATE ION, VANADIUM CHLOROPEROXIDASE
Authors:Macedo-Ribeiro, S, Messerschmidt, A.
Deposit date:1999-01-20
Release date:1999-08-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
1VNH
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BU of 1vnh by Molmil
CHLOROPEROXIDASE FROM THE FUNGUS CURVULARIA INAEQUALIS: MUTANT H496A
Descriptor: VANADATE ION, VANADIUM CHLOROPEROXIDASE
Authors:Macedo-Ribeiro, S, Messerschmidt, A.
Deposit date:1999-01-20
Release date:1999-08-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
1VNS
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BU of 1vns by Molmil
RECOMBINANT APO-CHLOROPEROXIDASE FROM CURVULARIA INAEQUALIS
Descriptor: SULFATE ION, VANADIUM CHLOROPEROXIDASE
Authors:Macedo-Ribeiro, S, Messerschmidt, A.
Deposit date:1999-01-14
Release date:1999-08-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
1VNI
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BU of 1vni by Molmil
CHLOROPEROXIDASE FROM THE FUNGUS CURVULARIA INAEQUALIS: RECOMBINANT HOLO-CHLOROPEROXIDASE
Descriptor: VANADATE ION, VANADIUM CHLOROPEROXIDASE
Authors:Macedo-Ribeiro, S, Messerschmidt, A.
Deposit date:1999-01-20
Release date:1999-08-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
2V70
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BU of 2v70 by Molmil
Third LRR domain of human Slit2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Authors:Morlot, C, Cusack, S, McCarthy, A.A.
Deposit date:2007-07-24
Release date:2007-08-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Production of Slit2 Lrr Domains in Mammalian Cells for Structural Studies and the Structure of Human Slit2 Domain 3.
Acta Crystallogr.,Sect.D, 63, 2007
3BB0
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BU of 3bb0 by Molmil
Crystal Structure of a Trapped Phosphate-Intermediate in Vanadium Apochloroperoxidase Catalyzing a Dephosphorylation Reaction
Descriptor: PHOSPHITE ION, SULFATE ION, Vanadium chloroperoxidase
Authors:Messerschmidt, A, Macedo-Ribeiro, S.
Deposit date:2007-11-09
Release date:2008-02-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of a trapped phosphate intermediate in vanadium apochloroperoxidase catalyzing a dephosphorylation reaction
Biochemistry, 47, 2008

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