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Crystal structure of human liver carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Cyclosarin (GF)
Descriptor:	Liver carboxylesterase 1, cyclohexyl (S)-methylphosphonofluoridoate
Authors:	Hemmert, A.C, Redinbo, M.R.
Deposit date:	2009-10-15
Release date:	2010-01-19
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin. Mol.Pharmacol., 77, 2010