Author results

6GV0
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INSULIN GLULISINE
Descriptor:Insulin, ZINC ION, FORMIC ACID
Authors:Chayen, N.E., Helliwell, J.R., Solomon-Gamsu, H.V., Govada, L., Morgan, M., Gillis, R.B., Adams, G.
Deposit date:2018-06-20
Release date:2019-07-03
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Insulin glulisine
To Be Published
6RO3
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2YR-X: LYSOZYME WITH RE CLUSTER 2 YEAR ON SHELF
Descriptor:Lysozyme C, CHLORIDE ION, SODIUM ION, ...
Authors:Brink, A., Helliwell, J.R.
Deposit date:2019-05-10
Release date:2019-06-19
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:Formation of a highly dense tetra-rhenium cluster in a protein crystal and its implications in medical imaging.
Iucrj, 6, 2019
6RO5
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1YR-Y: LYSOZYME WITH RE CLUSTER 1 YEAR ON SHELF
Descriptor:Lysozyme C, RHENIUM, CHLORIDE ION, ...
Authors:Brink, A., Helliwell, J.R.
Deposit date:2019-05-10
Release date:2019-06-19
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Formation of a highly dense tetra-rhenium cluster in a protein crystal and its implications in medical imaging.
Iucrj, 6, 2019
6GJT
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CHLAMYDIA PROTEIN PGP3 STUDIED AT HIGH RESOLUTION IN A NEW CRYSTAL FORM
Descriptor:Virulence plasmid protein pGP3-D, BROMIDE ION, POTASSIUM ION
Authors:Helliwell, J.R.
Deposit date:2018-05-17
Release date:2018-07-25
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Chlamydia protein Pgp3 studied at high resolution in a new crystal form.
IUCrJ, 5, 2018
5NBJ
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DLS TETRAGONAL - REHEWL
Descriptor:Lysozyme C, RHENIUM, CHLORIDE ION, ...
Authors:Brink, A., Helliwell, J.R.
Deposit date:2017-03-02
Release date:2017-05-10
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.266 Å)
Cite:New leads for fragment-based design of rhenium/technetium radiopharmaceutical agents.
IUCrJ, 4, 2017
5MIJ
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X-RAY STRUCTURE OF CARBOPLATIN-ENCAPSULATED HORSE SPLEEN APOFERRITIN
Descriptor:Ferritin light chain, CADMIUM ION, CHLORIDE ION, ...
Authors:Pontillo, N., Ferraro, G., Helliwell, J.R., Merlino, A.
Deposit date:2016-11-28
Release date:2017-03-15
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:X-ray Structure of the Carboplatin-Loaded Apo-Ferritin Nanocage.
ACS Med Chem Lett, 8, 2017
5MIK
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X-RAY STRUCTURE OF CARBOPLATIN-ENCAPSULATED HORSE SPLEEN APOFERRITIN (ROTATING ANODE DATA)
Descriptor:Ferritin light chain, CADMIUM ION, CHLORIDE ION, ...
Authors:Pontillo, N., Ferraro, G., Helliwell, J.R., Merlino, A.
Deposit date:2016-11-28
Release date:2017-03-15
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:X-ray Structure of the Carboplatin-Loaded Apo-Ferritin Nanocage.
ACS Med Chem Lett, 8, 2017
5M1Y
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THE CASE OF 1LKR HELD AT THE PDB AND ITS VARIABLE AMINO ACID OCCUPANCIES; RE REFINEMENT OF 4OW9 TO CORRECT THIS
Descriptor:Lysozyme C, PLATINUM (II) ION, IODIDE ION, ...
Authors:Helliwell, J.R.
Deposit date:2016-10-11
Release date:2016-10-26
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:The case of 1lkr held at the PDB and its variable amino acid occupancies; re refinement of 4ow9 to correct this
Zenodo, 2016
5LXW
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ATOMIC RESOLUTION X-RAY CRYSTAL STRUCTURE OF CISPLATIN BOUND TO HEN EGG WHITE LYSOZYME STORED FOR 5 YEARS ON THE SHELF
Descriptor:Lysozyme C, DIMETHYL SULFOXIDE, CHLORIDE ION, ...
Authors:Helliwell, J.R.
Deposit date:2016-09-22
Release date:2016-10-05
Method:X-RAY DIFFRACTION (1 Å)
Cite:Atomic resolution X-ray crystal structure of cisplatin bound to hen egg white lysozyme stored for 5 years 'on the shelf'
Zenodo, 2016
5L3H
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RE-REFINEMENT OF 4DD4; CISPLATIN COORDINATION CHEMISTRY DETERMINATION AT HEN EGG WHITE LYSOZYME HIS15 WITH STANDARD UNCERTAINTIES
Descriptor:Lysozyme C, CHLORIDE ION, SODIUM ION, ...
Authors:Helliwell, J.R., Tanley, S.W.M.
Deposit date:2016-05-06
Release date:2016-06-15
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cisplatin coordination chemistry determination at hen egg white lysozyme His15 with ligand distances and angles, and their standard uncertainties, and also reporting a split occupancy effect
ArXiv, 2016
5L3I
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RE-REFINEMENT OF 4DD6; CISPLATIN COORDINATION CHEMISTRY DETERMINATION AT HEN EGG WHITE LYSOZYME HIS15
Descriptor:Lysozyme C, DIMETHYL SULFOXIDE, SODIUM ION, ...
Authors:Helliwell, J.R.
Deposit date:2016-05-06
Release date:2016-06-15
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cisplatin coordination chemistry determination at hen egg white lysozyme His15 with ligand distances and angles, and their standard uncertainties, and also reporting a split occupancy effect
ArXiv, 2016
5HMV
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RE REFINEMENT OF 4MWK.
Descriptor:Lysozyme C, DIMETHYL SULFOXIDE, NITRATE ION, ...
Authors:Helliwell, J.R.
Deposit date:2016-01-17
Release date:2016-05-18
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Comment on "Structural dynamics of cisplatin binding to histidine in a protein" [Struct. Dyn. 1, 034701 (2014)].
Struct Dyn, 3, 2016
5HQ1
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COMMENT ON S. W. M. TANLEY AND J. R. HELLIWELL STRUCTURAL DYNAMICS OF CISPLATIN BINDING TO HISTIDINE IN A PROTEIN STRUCT. DYN. 1, 034701 (2014) REGARDING THE REFINEMENT OF 4MWK, 4MWM, 4MWN AND 4OXE AND THE METHOD WE HAVE ADOPTED.
Descriptor:Lysozyme C, DIMETHYL SULFOXIDE, CHLORIDE ION, ...
Authors:Helliwell, J.R.
Deposit date:2016-01-21
Release date:2016-05-18
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1 Å)
Cite:Comment on "Structural dynamics of cisplatin binding to histidine in a protein" [Struct. Dyn. 1, 034701 (2014)].
Struct Dyn, 3, 2016
5I5Q
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RE REFINEMENT OF 4MWN.
Descriptor:Lysozyme C, DIMETHYL SULFOXIDE, NITRATE ION, ...
Authors:Helliwell, J.R.
Deposit date:2016-02-15
Release date:2016-05-18
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Comment on "Structural dynamics of cisplatin binding to histidine in a protein" [Struct. Dyn. 1, 034701 (2014)].
Struct Dyn, 3, 2016
5IDD
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COMMENT ON S. W. M. TANLEY AND J. R. HELLIWELL STRUCTURAL DYNAMICS OF CISPLATIN BINDING TO HISTIDINE IN A PROTEIN STRUCT. DYN. 1, 034701 (2014) REGARDING THE REFINEMENT OF 4MWK, 4MWM, 4MWN AND 4OXE AND THE METHOD WE HAVE ADOPTED.
Descriptor:Lysozyme C, NITRATE ION, SODIUM ION, ...
Authors:Tanley, S.W.M., Helliwell, J.R.
Deposit date:2016-02-24
Release date:2016-05-18
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Comment on "Structural dynamics of cisplatin binding to histidine in a protein" [Struct. Dyn. 1, 034701 (2014)].
Struct Dyn., 3, 2016
5HLL
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RE-REFINEMENT OF 4G4A: ROOM-TEMPERATURE X-RAY DIFFRACTION STUDY OF CISPLATIN AND ITS BINDING TO HIS15 OF HEWL AFTER 14 MONTHS CHEMICAL EXPOSURE IN THE PRESENCE OF DMSO.
Descriptor:Lysozyme C, DIMETHYL SULFOXIDE, CHLORIDE ION, ...
Authors:Helliwell, J.R.
Deposit date:2016-01-15
Release date:2016-03-02
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Re-refinement of 4g4a: room-temperature X-ray diffraction study of cisplatin and its binding to His15 of HEWL after 14 months chemical exposure in the presence of DMSO.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5HMJ
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RE-REFINEMENT OF 4XAN: HEN LYSOZYME WITH CARBOPLATIN IN SODIUM BROMIDE SOLUTION
Descriptor:Lysozyme C, BROMIDE ION, SODIUM ION, ...
Authors:Helliwell, J.R.
Deposit date:2016-01-16
Release date:2016-03-02
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.299901 Å)
Cite:Re-refinement of 4xan: hen egg-white lysozyme with carboplatin in sodium bromide solution.
Acta Crystallogr F Struct Biol Commun, 72, 2016
4YTA
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BOND LENGTH ANALYSIS OF ASP, GLU AND HIS RESIDUES IN TRYPSIN AT 1.2A RESOLUTION
Descriptor:Cationic trypsin, GLYCEROL, SULFATE ION, ...
Authors:Fisher, S.J., Helliwell, J.R., Blakeley, M.P., Cianci, M., McSweeny, S.
Deposit date:2015-03-17
Release date:2015-05-27
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Protonation-state determination in proteins using high-resolution X-ray crystallography: effects of resolution and completeness.
Acta Crystallogr. D Biol. Crystallogr., 68, 2012
4YEM
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CARBOPLATIN BINDING TO HEWL IN NABR CRYSTALLISATION CONDITIONS STUDIED AT AN X-RAY WAVELENGTH OF 0.9163A - NEW REFINEMENT
Descriptor:Lysozyme C, PLATINUM (II) ION, BROMIDE ION, ...
Authors:Shabalin, I.G., Dauter, Z., Jaskolski, M., Minor, W., Wlodawer, A.
Deposit date:2015-02-24
Release date:2015-03-04
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin.
Acta Crystallogr.,Sect.D, 71, 2015
4YEN
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ROOM TEMPERATURE X-RAY DIFFRACTION STUDIES OF CISPLATIN BINDING TO HEWL IN DMSO MEDIA AFTER 14 MONTHS OF CRYSTAL STORAGE - NEW REFINEMENT
Descriptor:Lysozyme C, PLATINUM (II) ION, CHLORIDE ION, ...
Authors:Shabalin, I.G., Dauter, Z., Jaskolski, M., Minor, W., Wlodawer, A.
Deposit date:2015-02-24
Release date:2015-03-04
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin.
Acta Crystallogr.,Sect.D, 71, 2015
4YEO
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TRICLINIC HEWL CO-CRYSTALLISED WITH CISPLATIN, STUDIED AT A DATA COLLECTION TEMPERATURE OF 150K - NEW REFINEMENT
Descriptor:Lysozyme C, Cisplatin, PLATINUM (II) ION, ...
Authors:Shabalin, I.G., Dauter, Z., Jaskolski, M., Minor, W., Wlodawer, A.
Deposit date:2015-02-24
Release date:2015-03-04
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin.
Acta Crystallogr.,Sect.D, 71, 2015
4R6C
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X-RAY DIFFRACTION IN TEMPORALLY AND SPATIALLY RESOLVED BIOMOLECULAR SCIENCE: THE X-RAY CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME COCRYSTALLIZED WITH TA6BR12 AND THEN A CRYSTAL SOAKED IN K2PTBR6
Descriptor:Lysozyme C, HEXATANTALUM DODECABROMIDE, HEXABROMOPLATINATE(IV), ...
Authors:Helliwell, J.R.
Deposit date:2014-08-24
Release date:2015-02-04
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray diffraction in temporally and spatially resolved biomolecular science.
Faraday Discuss, 177, 2015
4NSG
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CARBOPLATIN BINDING TO HEWL IN NABR CRYSTALLISATION CONDITIONS STUDIED AT AN X-RAY WAVELENGTH OF 1.5418A
Descriptor:Lysozyme C, BROMIDE ION, SODIUM ION, ...
Authors:Tanley, S.W.M., Diederichs, K., Kroon-Batenburg, L.M.J., Levy, C., Schreurs, A.M.M., Helliwell, J.R.
Deposit date:2013-11-28
Release date:2014-10-15
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Carboplatin binding to histidine.
Acta Crystallogr F Struct Biol Commun, 70, 2014
4NSH
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CARBOPLATIN BINDING TO HEWL IN 0.2M NH4SO4, 0.1M NAAC IN 25% PEG 4000 AT PH 4.6
Descriptor:Lysozyme C, DIMETHYL SULFOXIDE, ACETATE ION, ...
Authors:Tanley, S.W.M., Diederichs, K., Kroon-Batenburg, L.M.J., Levy, C., Schreurs, A.M.M., Helliwell, J.R.
Deposit date:2013-11-28
Release date:2014-10-15
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Carboplatin binding to histidine.
Acta Crystallogr F Struct Biol Commun, 70, 2014
4NSI
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CARBOPLATIN BINDING TO HEWL IN 20% PROPANOL, 20% PEG 4000 AT PH5.6
Descriptor:Lysozyme C, DIMETHYL SULFOXIDE, carboplatin, ...
Authors:Tanley, S.W.M., Diederichs, K., Kroon-Batenburg, L.M.J., Levy, C., Schreurs, A.M.M., Helliwell, J.R.
Deposit date:2013-11-28
Release date:2014-10-15
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Carboplatin binding to histidine.
Acta Crystallogr F Struct Biol Commun, 70, 2014