2K31
 
 | | Solution Structure of cGMP-binding GAF domain of Phosphodiesterase 5 | | Descriptor: | GUANOSINE-3',5'-MONOPHOSPHATE, Phosphodiesterase 5A, cGMP-specific | | Authors: | Heikaus, C.C, Stout, J.R, Sekharan, M.R, Eakin, C.M, Rajagopal, P, Brzovic, P.S, Beavo, J.A, Klevit, R.E. | | Deposit date: | 2008-04-16 | | Release date: | 2008-06-03 | | Last modified: | 2021-10-20 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: Insights into Nucleotide Selectivity, Dimerization, and cGMP-Dependent Conformational Change.
J.Biol.Chem., 283, 2008
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3DBA
 | | Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C | | Descriptor: | Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', GLYCEROL, GUANOSINE-3',5'-MONOPHOSPHATE | | Authors: | Martinez, S.E, Heikaus, C.C, Klevit, R.E, Beavo, J.A. | | Deposit date: | 2008-05-30 | | Release date: | 2008-07-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change.
J.Biol.Chem., 283, 2008
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2LPB
 | | Structure of the complex of the central activation domain of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15 | | Descriptor: | General control protein GCN4, Mediator of RNA polymerase II transcription subunit 15 | | Authors: | Brzovic, P.S, Heikaus, C.C, Kisselev, L, Vernon, R, Herbig, E, Pacheco, D, Warfield, L, Littlefield, P, Baker, D, Klevit, R.E, Hahn, S. | | Deposit date: | 2012-02-07 | | Release date: | 2012-02-22 | | Method: | SOLUTION NMR | | Cite: | The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex.
Mol.Cell, 44, 2011
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