4NAG
 
 | | Xanthomonins I III are a New Class of Lasso Peptides Featuringa Seven-Membered Macrolactam Ring | | Descriptor: | HEXANE-1,6-DIOL, Xanthomonin I | | Authors: | Hegemann, J.D, Zimmermann, M, Zhu, S, Steuber, H, Harms, K, Xie, X, Marahiel, M.A. | | Deposit date: | 2013-10-22 | | Release date: | 2014-04-30 | | Last modified: | 2014-05-21 | | Method: | X-RAY DIFFRACTION (0.81 Å) | | Cite: | Xanthomonins I-III: A New Class of Lasso Peptides with a Seven-Residue Macrolactam Ring.
Angew.Chem.Int.Ed.Engl., 53, 2014
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2MFV
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2MMT
 | | Lasso peptide-based integrin inhibitor: Microcin J25 variant with RGDF substitution of Gly12-Ile13-Gly14-Thr15 | | Descriptor: | Microcin J25 RGDF mutant | | Authors: | Hegemann, J.D, Zimmermann, M, Knappe, T.A, Xie, X, Marahiel, M.A. | | Deposit date: | 2014-03-18 | | Release date: | 2014-07-02 | | Last modified: | 2014-07-23 | | Method: | SOLUTION NMR | | Cite: | Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides.
J.Med.Chem., 57, 2014
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2LX6
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5D9E
 | | Crystal Structure of the Proline-rich Lasso Peptide Caulosegnin II | | Descriptor: | CHLORIDE ION, Caulosegnin II | | Authors: | Fage, C.D, Hegemann, J.D, Harms, K, Marahiel, M.A. | | Deposit date: | 2015-08-18 | | Release date: | 2016-02-17 | | Last modified: | 2019-05-08 | | Method: | X-RAY DIFFRACTION (0.859 Å) | | Cite: | The ring residue proline 8 is crucial for the thermal stability of the lasso peptide caulosegnin II.
Mol Biosyst, 12, 2016
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5OQZ
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5JRK
 | | Crystal Structure of the Sphingopyxin I Lasso Peptide Isopeptidase SpI-IsoP (SeMet-derived) | | Descriptor: | Dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like protein, beta-D-glucopyranose | | Authors: | Fage, C.D, Hegemann, J.D, Bange, G, Marahiel, M.A. | | Deposit date: | 2016-05-06 | | Release date: | 2016-09-28 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase.
Angew.Chem.Int.Ed.Engl., 55, 2016
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5JRL
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5JQF
 | | Crystal structure of the lasso peptide Sphingopyxin I (SpI) | | Descriptor: | Sphingopyxin I | | Authors: | Fage, C.D, Hegemann, J.D, Harms, K, Bange, G, Marahiel, M.A. | | Deposit date: | 2016-05-04 | | Release date: | 2016-09-14 | | Last modified: | 2021-06-16 | | Method: | X-RAY DIFFRACTION (0.85 Å) | | Cite: | Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase.
Angew. Chem. Int. Ed. Engl., 55, 2016
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2M37
 | | Structure of lasso peptide astexin-1 | | Descriptor: | ASTEXIN-1 | | Authors: | Zimmermann, M, Hegemann, J.D, Xie, X, Marahiel, M.A. | | Deposit date: | 2013-01-14 | | Release date: | 2013-05-01 | | Method: | SOLUTION NMR | | Cite: | The astexin-1 lasso peptides: biosynthesis, stability, and structural studies.
Chem.Biol., 20, 2013
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2MLJ
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7WJ6
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7WJ7
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5DKI
 | | Yeast 20S proteasome in complex with alkyne-PI | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... | | Authors: | Beck, P, Cui, H, Groll, M. | | Deposit date: | 2015-09-03 | | Release date: | 2015-10-28 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation.
Chemmedchem, 10, 2015
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5DKJ
 | | Yeast 20S proteasome in complex with octreotide-PI | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... | | Authors: | Beck, P, Cui, H, Groll, M. | | Deposit date: | 2015-09-03 | | Release date: | 2015-10-28 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation.
Chemmedchem, 10, 2015
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