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6QLE
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BU of 6qle by Molmil
Structure of inner kinetochore CCAN complex
Descriptor: Central kinetochore subunit CTF3,Inner kinetochore subunit CTF3,Central kinetochore subunit CTF3,Inner kinetochore subunit CTF3, Central kinetochore subunit MCM16,Central kinetochore subunit MCM16,Inner kinetochore subunit MCM16,Mcm16p, Inner kinetochore subunit AME1,Inner kinetochore subunit AME1,Inner kinetochore subunit AME1,Inner kinetochore subunit AME1, ...
Authors:Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D.
Deposit date:2019-01-31
Release date:2019-10-02
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
6QLD
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BU of 6qld by Molmil
Structure of inner kinetochore CCAN-Cenp-A complex
Descriptor: DNA (125-MER), Histone H2A.1, Histone H2B.1, ...
Authors:Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D.
Deposit date:2019-01-31
Release date:2019-10-02
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
6QLF
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BU of 6qlf by Molmil
Structure of inner kinetochore CCAN complex with mask1
Descriptor: Inner kinetochore subunit AME1, Inner kinetochore subunit CHL4, Inner kinetochore subunit CTF19, ...
Authors:Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D.
Deposit date:2019-01-31
Release date:2019-10-02
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
1LQT
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BU of 1lqt by Molmil
A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase
Descriptor: 4-OXO-NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Bossi, R.T, Aliverti, A, Raimondi, D, Fischer, F, Zanetti, G, Ferrari, D, Tahallah, N, Maier, C.S, Heck, A.J.R, Rizzi, M, Mattevi, A, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-13
Release date:2002-07-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase.
Biochemistry, 41, 2002
1LQU
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BU of 1lqu by Molmil
Mycobacterium tuberculosis FprA in complex with NADPH
Descriptor: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, FprA, ...
Authors:Bossi, R.T, Aliverti, A, Raimondi, D, Fischer, F, Zanetti, G, Ferrari, D, Tahallah, N, Maier, C.S, Heck, A.J.R, Rizzi, M, Mattevi, A, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-13
Release date:2002-07-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase.
Biochemistry, 41, 2002
3ZNH
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BU of 3znh by Molmil
Crimean Congo Hemorrhagic Fever Virus OTU domain in complex with ubiquitin-propargyl.
Descriptor: POLYUBIQUITIN-B, UBIQUITIN THIOESTERASE
Authors:Ekkebus, R, vanKasteren, S.I, Kulathu, Y, Scholten, A, Berlin, I, deJong, A, Goerdayal, G, Neefjes, J, Heck, A.J.R, Komander, D, Ovaa, H.
Deposit date:2013-02-14
Release date:2013-02-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:On Terminal Alkynes that Can React with Active-Site Cysteine Nucleophiles in Proteases.
J.Am.Chem.Soc., 135, 2013
4BCA
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BU of 4bca by Molmil
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Tyr578Phe mutant
Descriptor: ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, CHLORIDE ION, ...
Authors:Nenci, S, Piano, V, Rosati, S, Aliverti, A, Pandini, V, Fraaije, M.W, Heck, A.J.R, Edmondson, D.E, Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BBY
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BU of 4bby by Molmil
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: WILD-TYPE
Descriptor: ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nenci, S, Piano, V, Rosati, S, Aliverti, A, Pandini, V, Fraaije, M.W, Heck, A.J.R, Edmondson, D.E, Mattevi, A.
Deposit date:2012-09-28
Release date:2012-11-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BC9
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BU of 4bc9 by Molmil
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: WILD-TYPE, ADDUCT WITH CYANOETHYL
Descriptor: ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nenci, S, Piano, V, Rosati, S, Aliverti, A, Pandini, V, Fraaije, M.W, Heck, A.J.R, Edmondson, D.E, Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BC7
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BU of 4bc7 by Molmil
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Arg419His mutant
Descriptor: 1-DODECANOL, ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, ...
Authors:Nenci, S, Piano, V, Rosati, S, Aliverti, A, Pandini, V, Fraaije, M.W, Heck, A.J.R, Edmondson, D.E, Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
5NBT
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BU of 5nbt by Molmil
Apo structure of p60N/p80C katanin
Descriptor: Katanin p60 ATPase-containing subunit A1, Katanin p80 WD40 repeat-containing subunit B1
Authors:Jiang, K, Rezabkova, L, Hua, S, Liu, Q, Capitani, G, Altelaar, A.F.M, Heck, A.J.R, Kammerer, R.A, Steinmetz, M.O, Akhmanova, A.
Deposit date:2017-03-02
Release date:2017-04-26
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.
Nat. Cell Biol., 19, 2017
5NMR
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BU of 5nmr by Molmil
Monomeric mouse Sortilin extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Leloup, N.O.L, Loessl, P, Meijer, D.H.M, Heck, A.J.R, Thies-Weesie, D.M.E, Janssen, B.J.C.
Deposit date:2017-04-07
Release date:2017-12-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.
Nat Commun, 8, 2017
8SNB
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BU of 8snb by Molmil
atomic model of sea urchin sperm doublet microtubule (48-nm periodicity)
Descriptor: ATP6V1FNB, C20Orf85, C4orf45, ...
Authors:Zeng, J, Zhang, R.
Deposit date:2023-04-26
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural specializations of the sperm tail.
Cell, 2023
6F3T
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BU of 6f3t by Molmil
Crystal structure of the human TAF5-TAF6-TAF9 complex
Descriptor: CHLORIDE ION, Transcription initiation factor TFIID subunit 5, Transcription initiation factor TFIID subunit 6, ...
Authors:Haffke, M, Berger, I.
Deposit date:2017-11-28
Release date:2018-12-05
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly.
Nat. Struct. Mol. Biol., 25, 2018
6T9C
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BU of 6t9c by Molmil
Crystal structure of the complex between PPARgamma LBD and the ligand NV1346 (3a)
Descriptor: 4-hexoxy-~{N}-[(2~{S})-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]benzamide, Peroxisome proliferator-activated receptor gamma
Authors:Pochetti, G, Montanari, R, Capelli, D.
Deposit date:2019-10-27
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Insights into PPAR gamma Phosphorylation and Its Inhibition Mechanism.
J.Med.Chem., 63, 2020
8OU0
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BU of 8ou0 by Molmil
bovine sperm endpiece singlet microtubules (one tubulin dimer and associated microtubule inner proteins)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Leung, M.R, Zeev-Ben-Mordehai, T.
Deposit date:2023-04-21
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural specializations of the sperm tail.
Cell, 186, 2023
8OTZ
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BU of 8otz by Molmil
48-nm repeat of the native axonemal doublet microtubule from bovine sperm
Descriptor: ATP6V1F neighbor, CFAP97 domain containing 1, Chromosome 13 C20orf85 homolog, ...
Authors:Leung, M.R, Zeng, J, Zhang, R, Zeev-Ben-Mordehai, T.
Deposit date:2023-04-21
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural specializations of the sperm tail.
Cell, 186, 2023
5HVZ
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BU of 5hvz by Molmil
Crystal structure of smAKAP AKB domain bound RIa dimerization/docking (D/D) complex at 2.0 A resolution
Descriptor: Small membrane A-kinase anchor protein, cAMP-dependent protein kinase type I-alpha regulatory subunit
Authors:Wu, J, Burgers, P.P, Bruystens, J, Heck, A.J.R, Taylor, S.S.
Deposit date:2016-01-28
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of smAKAP and its regulation by PKA-mediated phosphorylation.
Febs J., 283, 2016
6X9O
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BU of 6x9o by Molmil
High resolution cryoEM structure of huntingtin in complex with HAP40
Descriptor: 40-kDa huntingtin-associated protein, Huntingtin
Authors:Harding, R.J, Deme, J.C, Lea, S.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
Deposit date:2020-06-03
Release date:2020-06-17
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1.
Commun Biol, 4, 2021
5HYM
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BU of 5hym by Molmil
3-Hydroxybenzoate 6-hydroxylase from Rhodococcus jostii in complex with phosphatidylinositol
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Phosphatidylinositol, ...
Authors:Orru, R, Montersino, S, Mattevi, A, van Berkel, W.J.H.
Deposit date:2016-02-01
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor.
Front Microbiol, 8, 2017
6YN1
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BU of 6yn1 by Molmil
Crystal structure of histone chaperone APLF acidic domain bound to the histone H2A-H2B-H3-H4 octamer
Descriptor: Aprataxin and PNK-like factor, CHLORIDE ION, GLYCEROL, ...
Authors:Corbeski, I, Guo, X, Van Ingen, H, Sixma, T.K.
Deposit date:2020-04-10
Release date:2021-11-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF.
Sci Adv, 8, 2022
3T8X
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BU of 3t8x by Molmil
Crystal structure of human CD1b in complex with synthetic antigenic diacylsulfoglycolipid SGL12 and endogenous spacer
Descriptor: 2-O-sulfo-alpha-D-glucopyranosyl 2-O-hexadecanoyl-3-O-[(2E,4S,6S,8S)-2,4,6,8-tetramethyltetracos-2-enoyl]-alpha-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Garcia-Alles, L.F, Maveyraud, L, Mourey, L, Julien, S.
Deposit date:2011-08-02
Release date:2011-10-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural reorganization of the human CD1b Antigen-binding groove for presentation of mycobacterial sulfoglycolipids
To be Published
3TJ1
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BU of 3tj1 by Molmil
Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3
Descriptor: RNA polymerase I-specific transcription initiation factor RRN3
Authors:Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P.
Deposit date:2011-08-23
Release date:2011-09-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
7NYC
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BU of 7nyc by Molmil
cryoEM structure of 3C9-sMAC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Menny, A, Couves, E.C, Bubeck, D.
Deposit date:2021-03-22
Release date:2021-10-06
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
7NIE
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BU of 7nie by Molmil
putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria
Descriptor: Glycerol kinase, Voltage-dependent anion-selective channel protein 2
Authors:Leung, M.R, Zeev-Ben-Mordehai, T.
Deposit date:2021-02-12
Release date:2021-10-13
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (35 Å)
Cite:In-cell structures of conserved supramolecular protein arrays at the mitochondria-cytoskeleton interface in mammalian sperm.
Proc.Natl.Acad.Sci.USA, 118, 2021

 

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