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2AZ5
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BU of 2az5 by Molmil
Crystal Structure of TNF-alpha with a small molecule inhibitor
Descriptor: 6,7-DIMETHYL-3-[(METHYL{2-[METHYL({1-[3-(TRIFLUOROMETHYL)PHENYL]-1H-INDOL-3-YL}METHYL)AMINO]ETHYL}AMINO)METHYL]-4H-CHROMEN-4-ONE, Tumor necrosis factor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) (Cachectin) [Contains: Tumor necrosis factor, membrane form; Tumor necrosis factor, ...
Authors:He, M.M.
Deposit date:2005-09-09
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Small-molecule inhibition of TNF-alpha.
Science, 310, 2005
1FA6
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BU of 1fa6 by Molmil
CRYSTAL STRUCTURE OF THE CO(II)-BOUND GLYOXALASE I OF ESCHERICHIA COLI
Descriptor: COBALT (II) ION, GLYOXALASE I
Authors:He, M.M, Clugston, S.L, Honek, J.F, Matthews, B.W.
Deposit date:2000-07-12
Release date:2000-09-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation.
Biochemistry, 39, 2000
1F9Z
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BU of 1f9z by Molmil
CRYSTAL STRUCTURE OF THE NI(II)-BOUND GLYOXALASE I FROM ESCHERICHIA COLI
Descriptor: GLYOXALASE I, NICKEL (II) ION
Authors:He, M.M, Clugston, S.L, Honek, J.F, Matthews, B.W.
Deposit date:2000-07-11
Release date:2000-09-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation.
Biochemistry, 39, 2000
1FA8
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BU of 1fa8 by Molmil
CRYSTAL STRUCTURE OF THE APO FORM GLYOXALASE I OF ESCHERICHIA COLI
Descriptor: GLYOXALASE I
Authors:He, M.M, Clugston, S.L, Honek, J.F, Matthews, B.W.
Deposit date:2000-07-12
Release date:2000-09-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation.
Biochemistry, 39, 2000
1FA7
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BU of 1fa7 by Molmil
CRYSTAL STRUCTURE OF CD(II)-BOUND GLYOXALASE I OF ESCHERICHIA COLI
Descriptor: CADMIUM ION, GLYOXALASE I
Authors:He, M.M, Clugston, S.L, Honek, J.F, Matthews, B.W.
Deposit date:2000-07-12
Release date:2000-09-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation.
Biochemistry, 39, 2000
1FA5
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BU of 1fa5 by Molmil
CRYSTAL STRUCTURE OF THE ZN(II)-BOUND GLYOXALASE I OF ESCHERICHIA COLI
Descriptor: GLYOXALASE I, ZINC ION
Authors:He, M.M, Clugston, S.L, Honek, J.F, Matthews, B.W.
Deposit date:2000-07-12
Release date:2000-09-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation.
Biochemistry, 39, 2000
1SSW
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BU of 1ssw by Molmil
Crystal structure of phage T4 lysozyme mutant Y24A/Y25A/T26A/I27A/C54T/C97A
Descriptor: BETA-MERCAPTOETHANOL, Lysozyme
Authors:He, M.M, Baase, W.A, Xiao, H, Heinz, D.W, Matthews, B.W.
Deposit date:2004-03-24
Release date:2004-10-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation
Protein Sci., 13, 2004
1SSY
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BU of 1ssy by Molmil
Crystal structure of phage T4 lysozyme mutant G28A/I29A/G30A/C54T/C97A
Descriptor: Lysozyme
Authors:He, M.M, Baase, W.A, Xiao, H, Heinz, D.W, Matthews, B.W.
Deposit date:2004-03-24
Release date:2004-10-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation
Protein Sci., 13, 2004
1T8G
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BU of 1t8g by Molmil
Crystal structure of phage T4 lysozyme mutant L32A/L33A/T34A/C54T/C97A/E108V
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ...
Authors:He, M.M, Wood, Z.A, Baase, W.A, Xiao, H, Matthews, B.W.
Deposit date:2004-05-12
Release date:2004-10-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation.
Protein Sci., 13, 2004
1T8F
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BU of 1t8f by Molmil
Crystal structure of phage T4 lysozyme mutant R14A/K16A/I17A/K19A/T21A/E22A/C54T/C97A
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
Authors:He, M.M, Wood, Z.A, Baase, W.A, Xiao, H, Matthews, B.W.
Deposit date:2004-05-12
Release date:2004-10-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation.
Protein Sci., 13, 2004
3DAJ
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BU of 3daj by Molmil
Crystal structure of Aurora A complexed with an inhibitor discovered through site-directed dynamic tethering
Descriptor: N-butyl-3-{[6-(9H-purin-6-ylamino)hexanoyl]amino}benzamide, serine/threonine kinase 6
Authors:He, M.M.
Deposit date:2008-05-29
Release date:2008-07-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of an Aurora kinase inhibitor through site-specific dynamic combinatorial chemistry.
Bioorg.Med.Chem.Lett., 18, 2008
1NWE
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BU of 1nwe by Molmil
Ptp1B R47C Modified at C47 with N-[4-(2-{2-[3-(2-Bromo-acetylamino)-propionylamino]-3-hydroxy-propionylamino}-ethyl)-phenyl]-oxalamic acid
Descriptor: N-[4-(2-{2-[3-(2-BROMO-ACETYLAMINO)-PROPIONYLAMINO]-3-HYDROXY-PROPIONYLAMINO}-ETHYL)-PHENYL]-OXALAMIC ACID, Protein-tyrosine phosphatase, non-receptor type 1
Authors:Erlanson, D.A, McDowell, R.S, He, M.M, Randal, M, Simmons, R.L, Kung, J, Waight, A, Hansen, S.K.
Deposit date:2003-02-06
Release date:2003-05-06
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Discovery of a New Phosphotyrosine Mimetic for PTP1B Using Breakaway Tethering
J.Am.Chem.Soc., 125, 2003
1NWL
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BU of 1nwl by Molmil
Crystal structure of the PTP1B complexed with SP7343-SP7964, a pTyr mimetic
Descriptor: 3-(4-{2-[2-(2-BROMO-ACETYLAMINO)-ETHYLDISULFANYL]-ETHYLCARBAMOYL}-CYCLOHEXYLCARBAMOYL)-PYRAZINE-2-CARBOXYLIC ACID, MAGNESIUM ION, protein-tyrosine phosphatase, ...
Authors:Erlanson, D.A, McDowell, R.S, He, M.M, Randal, M, Simmons, R.L, Kung, J, Waight, A, Hansen, S.
Deposit date:2003-02-06
Release date:2003-04-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of a New Phosphotyrosine Mimetic for PTP1B Using Breakaway Tethering
J.Am.Chem.Soc., 125, 2003

217705

PDB entries from 2024-03-27

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