Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5JQ5
DownloadVisualize
BU of 5jq5 by Molmil
Crystal structure of CDK2 in complex with inhibitor ICEC0942
Descriptor: (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, ACETATE ION, Cyclin-dependent kinase 2
Authors:Hazel, P, Freemont, P.S.
Deposit date:2016-05-04
Release date:2017-02-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study.
ChemMedChem, 12, 2017
5JQ8
DownloadVisualize
BU of 5jq8 by Molmil
Crystal structure of CDK2 in complex with inhibitor ICEC0943
Descriptor: (3S,4S)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, Cyclin-dependent kinase 2
Authors:Hazel, P, Freemont, P.S.
Deposit date:2016-05-04
Release date:2017-02-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study.
ChemMedChem, 12, 2017
2AVJ
DownloadVisualize
BU of 2avj by Molmil
G4(Br)UTTG4 dimeric quadruplex
Descriptor: 5'-D(*GP*GP*GP*GP*(BRU)P*TP*TP*GP*GP*GP*G)-3', CACODYLATE ION, POTASSIUM ION
Authors:Hazel, P, Parkinson, G.N, Neidle, S.
Deposit date:2005-08-30
Release date:2006-03-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Topology variation and loop structural homology in crystal and simulated structures of a bimolecular DNA quadruplex.
J.Am.Chem.Soc., 128, 2006
2AVH
DownloadVisualize
BU of 2avh by Molmil
G4T3G4 dimeric quadruplex structure
Descriptor: 5'-D(*GP*GP*GP*GP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
Authors:Hazel, P, Parkinson, G.N, Neidle, S.
Deposit date:2005-08-30
Release date:2006-03-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Topology variation and loop structural homology in crystal and simulated structures of a bimolecular DNA quadruplex.
J.Am.Chem.Soc., 128, 2006
3NS9
DownloadVisualize
BU of 3ns9 by Molmil
Crystal structure of CDK2 in complex with inhibitor BS-194
Descriptor: (2S,3S)-3-{[7-(benzylamino)-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-5-yl]amino}butane-1,2,4-triol, Cell division protein kinase 2
Authors:Hazel, P, Freemont, P.S.
Deposit date:2010-07-01
Release date:2010-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:A Novel Pyrazolo[1,5-a]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration.
J.Med.Chem., 53, 2010
2GW0
DownloadVisualize
BU of 2gw0 by Molmil
A D(TGGGGT)- sodium and calcium complex.
Descriptor: 5'-D(*TP*GP*GP*GP*GP*T)-3', CALCIUM ION, SODIUM ION
Authors:Lee, M.P.H, Parkinson, G.N, Neidle, S.
Deposit date:2006-05-03
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Observation of the coexistence of sodium and calcium ions in a DNA G-quadruplex ion channel.
J.Am.Chem.Soc., 129, 2007

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon