Author results

1IQA
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MOUSE RANK LIGAND
Descriptor:RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B LIGAND
Authors:Ito, S., Wakabayashi, K., Ubukata, O., Hayashi, S., Okada, F., Hata, T.
Deposit date:2001-07-11
Release date:2002-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution.
J.Biol.Chem., 277, 2002
3VUO
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CRYSTAL STRUCTURE OF NONTOXIC NONHEMAGGLUTININ SUBCOMPONENT (NTNHA) FROM CLOSTRIDIUM BOTULINUM SEROTYPE D STRAIN 4947
Descriptor:NTNHA
Authors:Sagane, Y., Miyashita, S.-I., Miyata, K., Matsumoto, T., Inui, K., Hayashi, S., Suzuki, T., Hasegawa, K., Yajima, S., Yamano, A., Niwa, K., Watanabe, T.
Deposit date:2012-07-03
Release date:2012-09-19
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Small-angle X-ray scattering reveals structural dynamics of the botulinum neurotoxin associating protein, nontoxic nonhemagglutinin
Biochem.Biophys.Res.Commun., 425, 2012
5B2H
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CRYSTAL STRUCTURE OF HA33 FROM CLOSTRIDIUM BOTULINUM SEROTYPE C STRAIN YOICHI
Descriptor:HA-33, TRIETHYLENE GLYCOL
Authors:Akiyama, T., Hayashi, S., Matsumoto, T., Hasegawa, K., Yamano, A., Suzuki, T., Niwa, K., Watanabe, T., Sagane, Y., Yajima, S.
Deposit date:2016-01-15
Release date:2016-06-15
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational divergence in the HA-33/HA-17 trimer of serotype C and D botulinum toxin complex
Biochem.Biophys.Res.Commun., 476, 2016
1IRM
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CRYSTAL STRUCTURE OF APO HEME OXYGENASE-1
Descriptor:apo heme oxygenase-1
Authors:Sugishima, M., Sakamoto, H., Kakuta, Y., Omata, Y., Hayashi, S., Noguchi, M., Fukuyama, K.
Deposit date:2001-10-09
Release date:2002-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of rat apo-heme oxygenase-1 (HO-1): mechanism of heme binding in HO-1 inferred from structural comparison of the apo and heme complex forms
Biochemistry, 41, 2002
4YZI
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CRYSTAL STRUCTURE OF BLUE-SHIFTED CHANNELRHODOPSIN MUTANT (T198G/G202A)
Descriptor:Sensory opsin A,Archaeal-type opsin 2, RETINAL, OLEIC ACID, ...
Authors:Kato, H.E., Kamiya, M., Ishitani, R., Hayashi, S., Nureki, O.
Deposit date:2015-03-25
Release date:2015-05-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Atomistic design of microbial opsin-based blue-shifted optogenetics tools.
Nat Commun, 6, 2015
1IVJ
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CRYSTAL STRUCTURE OF RAT HEMEOXYGENASE-1 IN COMPLEX WITH HEME AND AZIDE.
Descriptor:Hemeoxygenase-1, AZIDE ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M., Sakamoto, H., Omata, Y., Hayashi, S., Noguchi, M., Fukuyama, K.
Deposit date:2002-03-18
Release date:2002-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme Bound to Azide. IMPLICATION FOR REGIOSPECIFIC HYDROXYLATION OF HEME AT THE alpha -MESO CARBON
J.Biol.Chem., 277, 2002
1IX3
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CRYSTAL STRUCTURE OF RAT HEME OXYGENASE-1 IN COMPLEX WITH HEME BOUND TO CYANIDE
Descriptor:HEME OXYGENASE-1, CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M., Sakamoto, H., Omata, Y., Hayashi, S., Noguchi, M., Fukuyama, K.
Deposit date:2002-06-10
Release date:2003-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1.
Biochemistry, 42, 2003
1IX4
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CRYSTAL STRUCTURE OF RAT HEME OXYGENASE-1 IN COMPLEX WITH HEME BOUND TO CARBON MONOXIDE
Descriptor:HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE
Authors:Sugishima, M., Sakamoto, H., Omata, Y., Hayashi, S., Noguchi, M., Fukuyama, K.
Deposit date:2002-06-10
Release date:2003-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1.
Biochemistry, 42, 2003
3B1M
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CRYSTAL STRUCTURE OF THE PPARGAMMA-LBD COMPLEXED WITH A CERCOSPORAMIDE DERIVATIVE MODULATOR CERCO-A
Descriptor:Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, (9aS)-8-acetyl-N-[(2-ethylnaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide
Authors:Matsui, Y., Hiroyuki, H.
Deposit date:2011-07-05
Release date:2011-08-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Pharmacology and in Vitro Profiling of a Novel Peroxisome Proliferator-Activated Receptor gamma Ligand, Cerco-A
Biol.Pharm.Bull., 34, 2011
3LMP
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CRYSTAL STRUCTURE OF THE PPARGAMMA-LBD COMPLEXED WITH A CERCOSPORAMIDE DERIVATIVE MODULATOR
Descriptor:Peroxisome proliferator-activated receptor gamma, Peptide of Nuclear receptor coactivator 1, (9aS)-8-acetyl-1,7-dihydroxy-3-methoxy-9a-methyl-N-(1-naphthylmethyl)-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide
Authors:Matsui, Y., Hanzawa, H.
Deposit date:2010-01-31
Release date:2010-04-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of a novel selective PPARgamma modulator from (-)-Cercosporamide derivatives
Bioorg.Med.Chem.Lett., 20, 2010
3V9T
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CRYSTAL STRUCTURE OF THE PPARGAMMA-LBD COMPLEXED WITH A CERCOSPORAMIDE DERIVATIVE MODULATOR
Descriptor:Peroxisome proliferator-activated receptor gamma, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, (9aS)-8-acetyl-N-[(3-ethoxynaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide
Authors:Matsui, Y., Hanzawa, H.
Deposit date:2011-12-28
Release date:2012-02-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPAR(gamma) partial agonists
Bioorg.Med.Chem.Lett., 22, 2012
3V9V
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CRYSTAL STRUCTURE OF THE PPARGAMMA-LBD COMPLEXED WITH A CERCOSPORAMIDE DERIVATIVE MODULATOR
Descriptor:Peroxisome proliferator-activated receptor gamma, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, methyl 3-{4-[({[(9aS)-8-acetyl-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-yl]carbonyl}amino)methyl]naphthalen-2-yl}propanoate
Authors:Matsui, Y., Hanzawa, H.
Deposit date:2011-12-28
Release date:2012-02-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPAR(gamma) partial agonists
Bioorg.Med.Chem.Lett., 22, 2011
3V9Y
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CRYSTAL STRUCTURE OF THE PPARGAMMA-LBD COMPLEXED WITH A CERCOSPORAMIDE DERIVATIVE MODULATOR
Descriptor:Peroxisome proliferator-activated receptor gamma, Peptide from Nuclear receptor coactivator 1, 4-{4-[({[(9aS)-8-acetyl-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-yl]carbonyl}amino)methyl]naphthalen-2-yl}butanoic acid
Authors:Matsui, Y., Hanzawa, H.
Deposit date:2011-12-28
Release date:2012-02-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPAR(gamma) partial agonists
Bioorg.Med.Chem.Lett., 22, 2012
4F9M
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CRYSTAL STRUCTURE OF THE PPARGAMMA-LBD COMPLEXED WITH A CERCOSPORAMIDE DERIVATIVE MODULATOR
Descriptor:Peroxisome proliferator-activated receptor gamma, peptide from Nuclear receptor coactivator 1, (9aS)-8-acetyl-N-[(2-ethyl-4-fluoronaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide
Authors:Matsui, Y., Hanzawa, H.
Deposit date:2012-05-19
Release date:2012-08-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis and biological evaluation of novel (-)-cercosporamide derivatives as potent selective PPARg modulators
Eur.J.Med.Chem., 54, 2012
5AVI
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CRYSTAL STRUCTURE OF LXRALPHA IN COMPLEX WITH TERT-BUTYL BENZOATE ANALOG, COMPOUND 4
Descriptor:Oxysterols receptor LXR-alpha, Nuclear receptor coactivator 1, tert-butyl 2-[[4-[ethanoyl(methyl)amino]phenoxy]methyl]-5-(trifluoromethyl)benzoate
Authors:Matsui, Y., Hanzawa, H., Tamaki, K.
Deposit date:2015-06-16
Release date:2015-08-26
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery and structure-guided optimization of tert-butyl 6-(phenoxymethyl)-3-(trifluoromethyl)benzoates as liver X receptor agonists
Bioorg.Med.Chem.Lett., 25, 2015
5AVL
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CRYSTAL STRUCTURE OF LXRALPHA IN COMPLEX WITH TERT-BUTYL BENZOATE ANALOG, COMPOUND 32B
Descriptor:Oxysterols receptor LXR-alpha, Nuclear receptor coactivator 1, 2-[4-[4-[[2-[(2-methylpropan-2-yl)oxycarbonyl]-3-oxidanyl-4-(trifluoromethyl)phenyl]methoxy]phenyl]phenyl]ethanoic acid
Authors:Matsui, Y., Hanzawa, H., Tamaki, K.
Deposit date:2015-06-17
Release date:2015-08-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery and structure-guided optimization of tert-butyl 6-(phenoxymethyl)-3-(trifluoromethyl)benzoates as liver X receptor agonists
Bioorg.Med.Chem.Lett., 25, 2015
5AZD
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CRYSTAL STRUCTURE OF THERMOPHILIC RHODOPSIN.
Descriptor:Bacteriorhodopsin
Authors:Mizutani, K., Hashimoto, N., Tsukamoto, T., Yamashita, K., Yamamoto, M., Sudo, Y., Murata, T.
Deposit date:2015-09-30
Release date:2016-04-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray crystallographic structure of thermophilic rhodopsin: implications for high thermal stability and optogenetic availability.
To Be Published
3UG9
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CRYSTAL STRUCTURE OF THE CLOSED STATE OF CHANNELRHODOPSIN
Descriptor:Archaeal-type opsin 1, Archaeal-type opsin 2, RETINAL, ...
Authors:Kato, H.E., Ishitani, R., Nureki, O.
Deposit date:2011-11-02
Release date:2012-01-25
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the channelrhodopsin light-gated cation channel
Nature, 482, 2012
5XTM
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CRYSTAL STRUCTURE OF PHORPP38 BOUND TO A K-TURN IN P12.2 HELIX
Descriptor:50S ribosomal protein L7Ae, RNA (47-MER), MAGNESIUM ION
Authors:Oshima, K., Kimura, M.
Deposit date:2017-06-20
Release date:2018-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the archaeal RNase P protein Rpp38 in complex with RNA fragments containing a K-turn motif.
Acta Crystallogr F Struct Biol Commun, 74, 2018
5Y7M
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CRYSTAL STRUCTURE OF PHORPP38 BOUND TO A K-TURN IN P12.1 HELIX
Descriptor:50S ribosomal protein L7Ae, RNA (52-MER), GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Oshima, K., Kimura, M.
Deposit date:2017-08-01
Release date:2018-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of the archaeal RNase P protein Rpp38 in complex with RNA fragments containing a K-turn motif.
Acta Crystallogr F Struct Biol Commun, 74, 2018