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4POL
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BU of 4pol by Molmil
Crystal structures of thioredoxin with mesna at 2.8A resolution
Descriptor: 1-THIOETHANESULFONIC ACID, Thioredoxin
Authors:Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H.
Deposit date:2014-02-26
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:BNP7787 Forms Novel Covalent Adducts on Human Thioredoxin and Modulates Thioredoxin Activity
J Pharmacol Clin Toxicol, 2, 2014
4POK
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BU of 4pok by Molmil
Crystal structures of thioredoxin with mesna at 2.5A resolution
Descriptor: 1-THIOETHANESULFONIC ACID, Thioredoxin
Authors:Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H.
Deposit date:2014-02-25
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:BNP7787 Forms Novel Covalent Adducts on Human Thioredoxin and Modulates Thioredoxin Activity
J Pharmacol Clin Toxicol, 2, 2014
4POM
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BU of 4pom by Molmil
Crystal structures of thioredoxin with mesna at 1.85A resolution
Descriptor: 1-THIOETHANESULFONIC ACID, Thioredoxin
Authors:Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H.
Deposit date:2014-02-26
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:BNP7787 Forms Novel Covalent Adducts on Human Thioredoxin and Modulates Thioredoxin Activity
J Pharmacol Clin Toxicol, 2, 2014
4RQR
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BU of 4rqr by Molmil
Crystal Structure of Human Glutaredoxin with MESNA
Descriptor: 1-THIOETHANESULFONIC ACID, Glutaredoxin-1
Authors:Badger, J, Sridhar, V, Logan, C, Hausheer, F.H, Nienaber, V.L.
Deposit date:2014-11-04
Release date:2015-04-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
Molecules, 20, 2015
4TT7
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BU of 4tt7 by Molmil
Crystal structure of human ALK with a covalent modification
Descriptor: 1,2-ETHANEDIOL, 1-THIOETHANESULFONIC ACID, ALK tyrosine kinase receptor
Authors:Badger, J, Sridhar, V, Chie-Leon, B, Nienaber, V.L, Hausheer, F.H.
Deposit date:2014-06-19
Release date:2015-02-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787.
Onco Targets Ther, 8, 2015
4RQX
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BU of 4rqx by Molmil
Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA
Descriptor: 1-THIOETHANESULFONIC ACID, Peroxiredoxin-4
Authors:Badger, J, Sridhar, V, Logan, C, Hausheer, F.H, Nienaber, V.L.
Deposit date:2014-11-05
Release date:2015-04-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.256 Å)
Cite:Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
Molecules, 20, 2015

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