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4LZF
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BU of 4lzf by Molmil
A novel domain in the microcephaly protein CPAP suggests a role in centriole architecture
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Centrosomal P4.1-associated protein, SCL-interrupting locus protein homolog, ...
Authors:Hatzopoulos, G.N, Erat, M.C, Cutts, E, Rogala, K, Slatter, L, Stansfeld, P.J, Vakonakis, I.
Deposit date:2013-07-31
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture.
Structure, 21, 2013
3I4O
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BU of 3i4o by Molmil
Crystal Structure of Translation Initiation Factor 1 from Mycobacterium tuberculosis
Descriptor: Translation initiation factor IF-1
Authors:Hatzopoulos, G.N, Mueller-Dieckmann, J.
Deposit date:2009-07-02
Release date:2010-02-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structure of translation initiation factor 1 from Mycobacterium tuberculosis and inferred binding to the 30S ribosomal subunit.
Febs Lett., 584, 2010
6ZZG
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BU of 6zzg by Molmil
MB_CRS6-1 bound to CrSAS-6_N
Descriptor: ACETATE ION, Centriole protein, MB_CRS6-15
Authors:Hatzopoulos, G.N, Kukenshoner, T, Banterle, N, Favez, T, Fluckiger, I, Hantschel, O, Gonczy, P.
Deposit date:2020-08-04
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly.
Nat Commun, 12, 2021
6ZZD
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BU of 6zzd by Molmil
MB_CRS6-13 bound to CrSAS-6_N
Descriptor: Centriole protein, MB_CRS6-13
Authors:Hatzopoulos, G.N, Kukenshoner, T, Banterle, N, Favez, T, Fluckiger, I, Hantschel, O, Gonczy, P.
Deposit date:2020-08-04
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly.
Nat Commun, 12, 2021
6ZZC
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BU of 6zzc by Molmil
MB_CRS6-1 bound to CrSAS-6_6HR
Descriptor: Centriole protein, DODECAETHYLENE GLYCOL, MB_CrS6-1
Authors:Hatzopoulos, G.N, Kukenshoner, T, Banterle, N, Favez, T, Fluckiger, I, Hantschel, O, Gonczy, P.
Deposit date:2020-08-04
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly.
Nat Commun, 12, 2021
6ZZ8
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BU of 6zz8 by Molmil
MB_CRS6-15 bound to CrSAS-6_6HR
Descriptor: Centriole protein, Protein B
Authors:Hatzopoulos, G.N, Kukenshoner, T, Banterle, N, Favez, T, Fluckiger, I, Hantschel, O, Gonczy, P.
Deposit date:2020-08-04
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.73 Å)
Cite:Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly.
Nat Commun, 12, 2021
4LD3
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BU of 4ld3 by Molmil
Structural analysis of the microcephaly protein CPAP G-box domain suggests a role in centriole elongation.
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, SCL-interrupting locus protein homolog, ...
Authors:Hatzopoulos, G.N, Vakonakis, I.
Deposit date:2013-06-24
Release date:2013-09-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture.
Structure, 21, 2013
4LD1
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BU of 4ld1 by Molmil
Structural analysis of the microcephaly protein CPAP G-box domain suggests a role in centriole elongation.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, NITRATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Hatzopoulos, G.N, Vakonakis, I.
Deposit date:2013-06-24
Release date:2013-09-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture.
Structure, 21, 2013
1Z6S
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BU of 1z6s by Molmil
Ribonuclease A- AMP complex
Descriptor: ADENOSINE MONOPHOSPHATE, Ribonuclease pancreatic
Authors:Hatzopoulos, G.N, Leonidas, D.D, Kardakaris, R, Kobe, J, Oikonomakos, N.G.
Deposit date:2005-03-23
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The binding of IMP to Ribonuclease A
Febs J., 272, 2005
1Z6D
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BU of 1z6d by Molmil
Ribonuclease A- IMP complex
Descriptor: INOSINIC ACID, Ribonuclease pancreatic
Authors:Hatzopoulos, G.N, Leonidas, D.D, Kardakaris, R, Kobe, J, Oikonomakos, N.G.
Deposit date:2005-03-22
Release date:2005-08-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:The binding of IMP to Ribonuclease A
Febs J., 272, 2005
4TS6
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BU of 4ts6 by Molmil
Crystal structure of the RIM C2A domain from Drosophila.
Descriptor: GLYCEROL, Rab3 interacting molecule variant 2
Authors:Hatzopoulos, G.N, Shiroma, J, Vakonakis, I.
Deposit date:2014-06-18
Release date:2015-07-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of the RIM C2A domain from Drosophila.
To Be Published
4YNH
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BU of 4ynh by Molmil
Structure of the C. elegans SAS-5 Implico dimerization domain
Descriptor: Spindle assembly abnormal protein 5
Authors:Rogala, K.B, Vakonakis, I, Hatzopoulos, G.N.
Deposit date:2015-03-10
Release date:2015-06-10
Last modified:2015-08-26
Method:X-RAY DIFFRACTION (1 Å)
Cite:The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation.
Elife, 4, 2015
4YV4
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BU of 4yv4 by Molmil
Structure of the C. elegans SAS-5 coiled coil domain
Descriptor: PHOSPHATE ION, SULFATE ION, Spindle assembly abnormal protein 5
Authors:Rogala, K.B, Hatzopoulos, G.N, Vakonakis, I.
Deposit date:2015-03-19
Release date:2015-06-10
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation.
Elife, 4, 2015
5FCM
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BU of 5fcm by Molmil
CrBld10-N 1-70
Descriptor: Basal body protein, ISOPROPYL ALCOHOL, SULFATE ION
Authors:Kraatz, S.H.W, Steinmetz, M.O.
Deposit date:2015-12-15
Release date:2016-07-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.229 Å)
Cite:The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding.
Structure, 24, 2016
5FCN
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BU of 5fcn by Molmil
microtubule binding domain of human CEP135
Descriptor: Centrosomal protein of 135 kDa
Authors:Kraatz, S.H.W.
Deposit date:2015-12-15
Release date:2016-07-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding.
Structure, 24, 2016
6YRL
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BU of 6yrl by Molmil
Structure of the Chlamydomonas reinhardtii SAS-6 coiled-coil domain, C2 crystal form
Descriptor: Centriole protein
Authors:Kantsadi, A.L, Vakonakis, I.
Deposit date:2020-04-20
Release date:2021-05-12
Last modified:2022-03-16
Method:X-RAY DIFFRACTION (2.343 Å)
Cite:Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 2022
6YRN
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BU of 6yrn by Molmil
Structure of the Chlamydomonas reinhardtii SAS-6 coiled-coil domain, P2 crystal form
Descriptor: Centriole protein, TETRAETHYLENE GLYCOL
Authors:Kantsadi, A.L, Vakonakis, I.
Deposit date:2020-04-20
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 2022
6YS4
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BU of 6ys4 by Molmil
Structure of the Homo sapiens SAS-6 coiled-coil domain
Descriptor: GLYCINE, Spindle assembly abnormal protein 6 homolog, TETRAETHYLENE GLYCOL
Authors:Kantsadi, A.L, Vakonakis, I.
Deposit date:2020-04-21
Release date:2021-05-12
Last modified:2022-03-16
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 2022
6Z26
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BU of 6z26 by Molmil
Structure of the Danio rerio SAS-6 coiled-coil domain
Descriptor: Spindle assembly abnormal protein 6 homolog
Authors:Kantsadi, A.L, Vakonakis, I.
Deposit date:2020-05-15
Release date:2021-05-26
Last modified:2022-05-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 30, 2022
4GFC
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BU of 4gfc by Molmil
N-terminal coiled-coil dimer of C.elegans SAS-6, crystal form B
Descriptor: 1,2-ETHANEDIOL, IMIDAZOLE, Spindle assembly abnormal protein 6, ...
Authors:Erat, M.C, Vakonakis, I.
Deposit date:2012-08-03
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GFA
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BU of 4gfa by Molmil
N-terminal coiled-coil dimer of C.elegans SAS-6, crystal form A
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Spindle assembly abnormal protein 6
Authors:Erat, M.C, Vakonakis, I.
Deposit date:2012-08-03
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4G79
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BU of 4g79 by Molmil
Structure a C. elegans SAS-6 variant
Descriptor: GLYCEROL, Spindle assembly abnormal protein 6, TETRAETHYLENE GLYCOL
Authors:Erat, M.C, Vakonakis, I.
Deposit date:2012-07-20
Release date:2013-06-19
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GEX
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BU of 4gex by Molmil
Structure of a stabilised ceSAS-6 dimer, second crystal form
Descriptor: SULFATE ION, Spindle assembly abnormal protein 6
Authors:Erat, M.C, Vakonakis, I.
Deposit date:2012-08-02
Release date:2013-06-19
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GEU
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BU of 4geu by Molmil
Structure of a stabilised ceSAS-6 dimer
Descriptor: GLYCEROL, Spindle assembly abnormal protein 6, TETRAETHYLENE GLYCOL
Authors:Erat, M.C, Vakonakis, I.
Deposit date:2012-08-02
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
4TPZ
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BU of 4tpz by Molmil
N-terminal domain of C. Reinhardtii SAS-6 homolog bld12p F145W (NN2)
Descriptor: Centriole protein
Authors:Hilbert, M, Kraatz, S.H.W.
Deposit date:2014-06-10
Release date:2015-06-24
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nat.Cell Biol., 18, 2016

 

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