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2QDJ
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BU of 2qdj by Molmil
Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture
Descriptor: Retinoblastoma-associated protein
Authors:Hassler, M, Mittnacht, S, Pearl, L.H.
Deposit date:2007-06-21
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture.
Mol.Cell, 28, 2007
1HBX
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BU of 1hbx by Molmil
Ternary Complex of SAP-1 and SRF with specific SRE DNA
Descriptor: 5'-D(*CP*AP*CP*AP*CP*CP*GP*GP*AP*AP*GP*TP*CP* CP*TP*AP*AP*TP*TP*AP*GP*GP*CP*CP*AP*T)-3', 5'-D(*GP*AP*TP*GP*GP*CP*CP*TP*AP*AP*TP*TP*AP* GP*GP*AP*CP*TP*TP*CP*CP*GP*GP*TP*G)-3', ETS-DOMAIN PROTEIN ELK-4, ...
Authors:Hassler, M, Richmond, T.J.
Deposit date:2001-04-20
Release date:2001-06-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The B-Box Dominates Sap-1/Srf Interactions in the Structure of the Ternary Complex
Embo J., 20, 2001
6QJ4
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BU of 6qj4 by Molmil
Crystal structure of the C. thermophilum condensin Ycs4-Brn1 subcomplex bound to the Smc4 ATPase head in complex with the C-terminal domain of Brn1
Descriptor: Brn1, Condensin complex subunit 1,Condensin complex subunit 1,Condensin complex subunit 1, Condensin complex subunit 2, ...
Authors:Hassler, M, Haering, C.H, Kschonsak, M.
Deposit date:2019-01-22
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (5.8 Å)
Cite:Structural Basis of an Asymmetric Condensin ATPase Cycle.
Mol.Cell, 74, 2019
6QJ3
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BU of 6qj3 by Molmil
Crystal structure of the C. thermophilum condensin Ycs4-Brn1 subcomplex
Descriptor: Brn1, Condensin complex subunit 1,Condensin complex subunit 1,Ycs4, Condensin complex subunit 2
Authors:Hassler, M, Haering, C.H, Kschonsak, M.
Deposit date:2019-01-22
Release date:2019-07-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Basis of an Asymmetric Condensin ATPase Cycle.
Mol.Cell, 74, 2019
6QJ2
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BU of 6qj2 by Molmil
Crystal structure of the C. thermophilum condensin Smc4 ATPase head in complex with the C-terminal domain of Brn1
Descriptor: Condensin complex subunit 2, SULFATE ION, Smc4
Authors:Hassler, M, Haering, C.H.
Deposit date:2019-01-22
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis of an Asymmetric Condensin ATPase Cycle.
Mol.Cell, 74, 2019
6QJ0
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BU of 6qj0 by Molmil
Crystal structure of the C. thermophilum condensin Smc2 ATPase head (crystal form II)
Descriptor: Structural maintenance of chromosomes protein,Structural maintenance of chromosomes protein
Authors:Hassler, M, Haering, C.H.
Deposit date:2019-01-22
Release date:2019-07-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis of an Asymmetric Condensin ATPase Cycle.
Mol.Cell, 74, 2019
6QJ1
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BU of 6qj1 by Molmil
Crystal structure of the C. thermophilum condensin Smc2 ATPase head (crystal from I)
Descriptor: Structural maintenance of chromosomes protein,Structural maintenance of chromosomes protein
Authors:Hassler, M, Haering, C.H.
Deposit date:2019-01-22
Release date:2019-07-03
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural Basis of an Asymmetric Condensin ATPase Cycle.
Mol.Cell, 74, 2019
3TE6
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BU of 3te6 by Molmil
Crystal Structure of the S. cerevisiae Sir3 AAA+ domain
Descriptor: Regulatory protein SIR3
Authors:Hassler, M, Ladurner, A.G.
Deposit date:2011-08-12
Release date:2011-08-31
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (2.8001 Å)
Cite:Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79.
Genes Dev., 25, 2011
6Q6E
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BU of 6q6e by Molmil
Structural and functional insights into the condensin ATPase cycle
Descriptor: Condensin complex subunit 2,Structural maintenance of chromosomes protein,Structural maintenance of chromosomes protein
Authors:Simon, B, Hassler, M, Haering, C.H, Hennig, J.
Deposit date:2018-12-10
Release date:2019-07-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis of an Asymmetric Condensin ATPase Cycle.
Mol.Cell, 74, 2019
6YVU
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BU of 6yvu by Molmil
Condensin complex from S.cerevisiae ATP-free apo non-engaged state
Descriptor: Condensin complex subunit 1,Condensin complex subunit 1,Ycs4, Condensin complex subunit 2,Condensin complex subunit 2,Brn1, Structural maintenance of chromosomes protein 2,Structural maintenance of chromosomes protein 2,Smc2, ...
Authors:Lee, B.-G, Cawood, C, Gutierrez-Escribano, P, Nakane, T, Merkel, F, Hassler, M, Aragon, L, Haering, C.H, Lowe, J.
Deposit date:2020-04-28
Release date:2020-07-15
Last modified:2020-08-19
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Nat.Struct.Mol.Biol., 27, 2020
6YVV
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BU of 6yvv by Molmil
Condensin complex from S.cerevisiae ATP-free apo bridged state
Descriptor: Condensin complex subunit 1,Ycs4, Condensin complex subunit 2,Brn1, Structural maintenance of chromosomes protein 2,Structural maintenance of chromosomes protein 2, ...
Authors:Lee, B.-G, Cawood, C, Gutierrez-Escribano, P, Nakane, T, Merkel, F, Hassler, M, Haering, C.H, Aragon, L, Lowe, J.
Deposit date:2020-04-28
Release date:2020-07-15
Last modified:2020-08-19
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Nat.Struct.Mol.Biol., 27, 2020
6YVD
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BU of 6yvd by Molmil
Head segment of the S.cerevisiae condensin holocomplex in presence of ATP
Descriptor: Condensin complex subunit 2, Condensin complex subunit 3, Structural maintenance of chromosomes protein 2, ...
Authors:Merkel, F, Haering, C.H, Hassler, M, Lee, B.G, Lowe, J.
Deposit date:2020-04-28
Release date:2020-07-22
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Nat.Struct.Mol.Biol., 27, 2020
4AV1
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BU of 4av1 by Molmil
Crystal structure of the human PARP-1 DNA binding domain in complex with DNA
Descriptor: 5'-D(*AP*AP*GP*TP*GP*TP*TP*GP*CP*AP*TP*TP)-3', 5'-D(*TP*AP*AP*TP*GP*CP*AP*AP*CP*AP*CP*TP)-3', POLY [ADP-RIBOSE] POLYMERASE 1, ...
Authors:Ali, A.A.E, Timinszky, G, Arribas-Bosacoma, R, Kozlowski, M, Hassa, P.O, Hassler, M, Ladurner, A.G, Pearl, L.H, Oliver, A.W.
Deposit date:2012-05-23
Release date:2012-06-13
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Zinc-Finger Domains of Parp1 Cooperate to Recognise DNA Strand-Breaks
Nat.Struct.Mol.Biol., 19, 2012
7QFW
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BU of 7qfw by Molmil
S.c. Condensin peripheral Ycg1 subcomplex bound to DNA
Descriptor: Condensin complex subunit 2, Condensin complex subunit 3, Synthetic DNA ligand, ...
Authors:Lecomte, L, Hassler, M, Haering, C, Eustermann, S.
Deposit date:2021-12-06
Release date:2022-06-15
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
Science, 376, 2022
7QEN
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BU of 7qen by Molmil
S.c. Condensin core in DNA- and ATP-bound state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Condensin complex subunit 1, Condensin complex subunit 2, ...
Authors:Lecomte, L, Hassler, M, Haering, C, Eustermann, S.
Deposit date:2021-12-03
Release date:2022-06-15
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
Science, 376, 2022
4KHA
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BU of 4kha by Molmil
Structural basis of histone H2A-H2B recognition by the essential chaperone FACT
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Histone H2A, ...
Authors:Hondele, M, Halbach, F, Hassler, M, Ladurner, A.G.
Deposit date:2013-04-30
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis of histone H2A-H2B recognition by the essential chaperone FACT.
Nature, 499, 2013
4IQY
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BU of 4iqy by Molmil
Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MacroD2
Descriptor: MAGNESIUM ION, O-acetyl-ADP-ribose deacetylase MACROD2, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Jankevicius, G, Hassler, M, Golia, B, Rybin, V, Zacharias, M, Timinszky, G, Ladurner, A.G.
Deposit date:2013-01-14
Release date:2013-03-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A family of macrodomain proteins reverses cellular mono-ADP-ribosylation.
Nat.Struct.Mol.Biol., 20, 2013
3ZCO
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BU of 3zco by Molmil
Crystal structure of S. cerevisiae Sir3 C-terminal domain
Descriptor: REGULATORY PROTEIN SIR3
Authors:Oppikofer, M, Kueng, S, Keusch, J.J, Hassler, M, Ladurner, A.G, Gut, H, Gasser, S.M.
Deposit date:2012-11-21
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dimerization of Sir3 Via its C-Terminal Winged Helix Domain is Essential for Yeast Heterochromatin Formation.
Embo J., 32, 2013
2V7E
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BU of 2v7e by Molmil
Crystal structure of coactivator-associated arginine methyltransferase 1 (CARM1), unliganded
Descriptor: HISTONE-ARGININE METHYLTRANSFERASE CARM1, MERCURY (II) ION
Authors:Yue, W.W, Hassler, M, Roe, S.M, Thompson-Vale, V, Pearl, L.H.
Deposit date:2007-07-30
Release date:2007-10-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Insights Into Histone Code Syntax from Structural and Biochemical Studies of Carm1 Methyltransferase
Embo J., 26, 2007
2V74
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BU of 2v74 by Molmil
Crystal structure of coactivator-associated arginine methyltransferase 1 (CARM1), in complex with S-adenosyl-homocysteine
Descriptor: HISTONE-ARGININE METHYLTRANSFERASE CARM1, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Yue, W.W, Hassler, M, Roe, S.M, Thompson-Vale, V, Pearl, L.H.
Deposit date:2007-07-26
Release date:2007-10-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Insights Into Histone Code Syntax from Structural and Biochemical Studies of Carm1 Methyltransferase
Embo J., 26, 2007
5OQO
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BU of 5oqo by Molmil
Crystal structure of the S. cerevisiae condensin Ycg1-Brn1 subcomplex bound to DNA (crystal form II)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Condensin complex subunit 2, Condensin complex subunit 3, ...
Authors:Kschonsak, M, Hassler, M, Haering, C.H.
Deposit date:2017-08-14
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes.
Cell, 171, 2017
5OQN
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BU of 5oqn by Molmil
Crystal structure of the S. cerevisiae condensin Ycg1-Brn1 subcomplex bound to DNA (short kleisin loop)
Descriptor: Condensin complex subunit 2, Condensin complex subunit 3, DNA (5'-D(*GP*AP*TP*GP*TP*GP*TP*AP*GP*CP*TP*AP*CP*AP*CP*AP*TP*C)-3')
Authors:Kschonsak, M, Hassler, M, Haering, C.H.
Deposit date:2017-08-14
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes.
Cell, 171, 2017
5OQQ
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BU of 5oqq by Molmil
Crystal structure of the S. cerevisiae condensin Ycg1-Brn1 subcomplex
Descriptor: Condensin complex subunit 2, Condensin complex subunit 3
Authors:Kschonsak, M, Hassler, M, Haering, C.H.
Deposit date:2017-08-14
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes.
Cell, 171, 2017
5OQR
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BU of 5oqr by Molmil
Crystal structure of the S. pombe condensin Cnd3-Cnd2 subcomplex
Descriptor: Condensin complex subunit 2, Condensin complex subunit 3
Authors:Kschonsak, M, Hassler, M, Haering, C.H.
Deposit date:2017-08-14
Release date:2017-10-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes.
Cell, 171, 2017
5OQP
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BU of 5oqp by Molmil
Crystal structure of the S. cerevisiae condensin Ycg1-Brn1 subcomplex bound to DNA (crystal form I)
Descriptor: Condensin complex subunit 2, Condensin complex subunit 3, DNA (5'-D(*GP*AP*TP*GP*TP*GP*TP*AP*GP*CP*TP*AP*CP*AP*CP*AP*TP*C)-3'), ...
Authors:Kschonsak, M, Hassler, M, Haering, C.H.
Deposit date:2017-08-14
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes.
Cell, 171, 2017

 

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PDB entries from 2024-03-27

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