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3B3F
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THE 2.2 A CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COACTIVATOR-ASSOCIATED ARGININE METHYL TRANSFERASE I(CARM1,142-478), IN COMPLEX WITH S-ADENOSYL HOMOCYSTEINE
Descriptor:Histone-arginine methyltransferase CARM1, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Troffer-Charlier, N., Cura, V., Hassenboehler, P., Moras, D., Cavarelli, J.
Deposit date:2007-10-22
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains.
Embo J., 26, 2007
3B3G
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THE 2.4 A CRYSTAL STRUCTURE OF THE APO CATALYTIC DOMAIN OF COACTIVATOR-ASSOCIATED ARGININE METHYL TRANSFERASE I(CARM1,140-480).
Descriptor:Histone-arginine methyltransferase CARM1
Authors:Troffer-Charlier, N., Cura, V., Hassenboehler, P., Moras, D., Cavarelli, J.
Deposit date:2007-10-22
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains.
Embo J., 26, 2007
3B3J
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THE 2.55 A CRYSTAL STRUCTURE OF THE APO CATALYTIC DOMAIN OF COACTIVATOR-ASSOCIATED ARGININE METHYL TRANSFERASE I(CARM1:28-507, RESIDUES 28-146 AND 479-507 NOT ORDERED)
Descriptor:Histone-arginine methyltransferase CARM1, BENZAMIDINE
Authors:Troffer-Charlier, N., Cura, V., Hassenboehler, P., Moras, D., Cavarelli, J.
Deposit date:2007-10-22
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains.
Embo J., 26, 2007
5LKJ
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH LIGAND SA684
Descriptor:Histone-arginine methyltransferase CARM1, (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(2-carbamimidamidoethyl)amino]-2-azanyl-butanoic acid, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-07-22
Release date:2017-08-16
Method:X-RAY DIFFRACTION (2.595 Å)
Cite:Crystal structure of mouse CARM1 in complex with ligands
To Be Published
2OQB
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF COACTIVATOR-ASSOCIATED METHYLTRANSFERASE 1 (CARM1)
Descriptor:Histone-arginine methyltransferase CARM1, CHLORIDE ION
Authors:Cavarelli, J.
Deposit date:2007-01-31
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains.
Embo J., 26, 2007
5IH3
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH SAH AT 1.8 ANGSTROMS RESOLUTION
Descriptor:Histone-arginine methyltransferase CARM1, S-ADENOSYL-L-HOMOCYSTEINE, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-02-29
Release date:2017-03-29
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of mouse CARM1 in complex with SAH at 1.8 Angstroms resolution
To Be Published
5IS6
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH SINEFUNGIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor:Histone-arginine methyltransferase CARM1, TETRAETHYLENE GLYCOL, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.007 Å)
Cite:Crystal structure of mouse CARM1 in complex with Sinefungin at 2.0 Angstroms resolution
To Be Published
5IS7
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH DECARBOXYLATED SAH
Descriptor:Histone-arginine methyltransferase CARM1, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structure of mouse CARM1 in complex with decarboxylated SAH
To Be Published
5IS8
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0271
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl](2-chloroethyl)amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.709 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0271
To Be Published
5IS9
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0375
Descriptor:Histone-arginine methyltransferase CARM1, (2S)-2-amino-4-[(3-{4-[(2S)-2-amino-2-carboxyethyl]-1H-1,2,3-triazol-1-yl}propyl){[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}amino]butanoic acid (non-preferred name), 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0375
To Be Published
5ISA
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0401
Descriptor:Histone-arginine methyltransferase CARM1, (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(3-azidopropyl)amino]-2-azanyl-butanoic acid, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0401
To Be Published
5ISB
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0435
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl][(1H-imidazol-4-yl)methyl]amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0435
To Be Published
5ISC
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0491
Descriptor:Histone-arginine methyltransferase CARM1, 5'-S-[(3S)-3-azaniumyl-3-carboxypropyl]-5'-thioadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0491
To Be Published
5ISD
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0592
Descriptor:Histone-arginine methyltransferase CARM1, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0592
To Be Published
5ISE
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0649
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl](3-carbamimidamidopropyl)amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of mouse CARM1 in complex with SAH at 1.8 Angstroms resolution
To Be Published
5ISF
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0705
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{[(3S)-3-amino-3-carboxypropyl][2-(triazan-1-yl)ethyl]amino}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0705
To Be Published
5ISG
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0707
Descriptor:Histone-arginine methyltransferase CARM1, 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.418 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0707
To Be Published
5ISH
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0765
Descriptor:Histone-arginine methyltransferase CARM1, 5'-{1-[(3S)-3-amino-3-carboxypropyl]aziridin-1-ium-1-yl}-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.152 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0765
To Be Published
5ISI
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0920 (5'-AMINO-5'-DEOXYADENOSINE)
Descriptor:Histone-arginine methyltransferase CARM1, 5'-amino-5'-deoxyadenosine, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-03-15
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:To be published
To Be Published
5K8V
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CRYSTAL STRUCTURE OF MUS MUSCULUS PROTEIN ARGININE METHYLTRANSFERASE 4 (CARM1 130-487) WITH CP1
Descriptor:Histone-arginine methyltransferase CARM1, [[2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethylamino]-azanyl-methylidene]azanium, 1,2-DIMETHOXYETHANE, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-05-31
Release date:2016-11-09
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors.
FEBS J., 284, 2017
5K8W
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR U2
Descriptor:Histone-arginine methyltransferase CARM1, 9-(7-{[amino(iminio)methyl]amino}-5,6,7-trideoxy-beta-D-ribo-heptofuranosyl)-9H-purin-6-amine, 1,2-DIMETHOXYETHANE, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-05-31
Release date:2017-06-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor U2
To Be Published
5K8X
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR U3
Descriptor:Histone-arginine methyltransferase CARM1, [[[(~{E})-3-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]prop-2-enyl]amino]-azanyl-methylidene]azanium, 1,2-ETHANEDIOL, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2016-05-31
Release date:2017-06-21
Method:X-RAY DIFFRACTION (1.991 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor U3
To Be Published
5NTC
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CRYSTAL STRUCTURE OF MOUSE CARM1 IN COMPLEX WITH INHIBITOR SA0678
Descriptor:Histone-arginine methyltransferase CARM1, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Hassenboehler, P., Wurtz, J.M., Bonnefond, L., Cavarelli, J.
Deposit date:2017-04-27
Release date:2018-05-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of mouse CARM1 in complex with inhibitor SA0678
To Be Published