Author results

1PX5
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CRYSTAL STRUCTURE OF THE 2'-SPECIFIC AND DOUBLE-STRANDED RNA-ACTIVATED INTERFERON-INDUCED ANTIVIRAL PROTEIN 2'-5'-OLIGOADENYLATE SYNTHETASE
Descriptor:2'-5'-oligoadenylate synthetase 1, SULFATE ION
Authors:Hartmann, R., Justesen, J., Sarkar, S.N., Sen, G.C., Yee, V.C.
Deposit date:2003-07-02
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Mol.Cell, 12, 2003
4AC5
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LIPIDIC SPONGE PHASE CRYSTAL STRUCTURE OF THE BL. VIRIDIS REACTION CENTRE SOLVED USING SERIAL FEMTOSECOND CRYSTALLOGRAPHY
Descriptor:PHOTOSYNTHETIC REACTION CENTER CYTOCHROME C SUBUNIT, REACTION CENTER PROTEIN H CHAIN, REACTION CENTER PROTEIN L CHAIN, ...
Authors:Johansson, L.C., Arnlund, D., White, T.A., Katona, G., DePonte, D.P., Weierstall, U., Doak, R.B., Shoeman, R.L., Lomb, L., Malmerberg, E., Davidsson, J., Nass, K., Liang, M., Andreasson, J., Aquila, A., Bajt, S., Barthelmess, M., Barty, A., Bogan, M.J., Bostedt, C., Bozek, J.D., Caleman, C., Coffee, R., Coppola, N., Ekeberg, T., Epp, S.W., Erk, B., Fleckenstein, H., Foucar, L., Graafsma, H., Gumprecht, L., Hajdu, J., Hampton, C.Y., Hartmann, R., Hartmann, A., Hauser, G., Hirsemann, H., Holl, P., Hunter, M.S., Kassemeyer, S., Kimmel, N., Kirian, R.A., Maia, F.R.N.C., Marchesini, S., Martin, A.V., Reich, C., Rolles, D., Rudek, B., Rudenko, A., Schlichting, I., Schulz, J., Seibert, M.M., Sierra, R., Soltau, H., Starodub, D., Stellato, F., Stern, S., Struder, L., Timneanu, N., Ullrich, J., Wahlgren, W.Y., Wang, X., Weidenspointner, G., Wunderer, C., Fromme, P., Chapman, H.N., Spence, J.C.H., Neutze, R.
Deposit date:2011-12-14
Release date:2012-02-15
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (8.2 Å)
Cite:Lipidic Phase Membrane Protein Serial Femtosecond Crystallography.
Nat.Methods, 9, 2012
3PCQ
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FEMTOSECOND X-RAY PROTEIN NANOCRYSTALLOGRAPHY
Descriptor:Photosystem I P700 chlorophyll a apoprotein A1, Photosystem I P700 chlorophyll a apoprotein A2, Photosystem I iron-sulfur center, ...
Authors:Chapman, H.N., Fromme, P., Barty, A., White, T.A., Kirian, R.A., Aquila, A., Hunter, M.S., Schulz, J., Deponte, D.P., Weierstall, U., Doak, R.B., Maia, F.R.N.C., Martin, A.V., Schlichting, I., Lomb, L., Coppola, N., Shoeman, R.L., Epp, S.W., Hartmann, R., Rolles, D., Rudenko, A., Foucar, L., Kimmel, N., Weidenspointner, G., Holl, P., Liang, M., Barthelmess, M., Caleman, C., Boutet, S., Bogan, M.J., Krzywinski, J., Bostedt, C., Bajt, S., Gumprecht, L., Rudek, B., Erk, B., Schmidt, C., Homke, A., Reich, C., Pietschner, D., Struder, L., Hauser, G., Gorke, H., Ullrich, J., Herrmann, S., Schaller, G., Schopper, F., Soltau, H., Kuhnel, K.-U., Messerschmidt, M., Bozek, J.D., Hau-Riege, S.P., Frank, M., Hampton, C.Y., Sierra, R., Starodub, D., Williams, G.J., Hajdu, J., Timneanu, N., Seibert, M.M., Andreasson, J., Rocker, A., Jonsson, O., Svenda, M., Stern, S., Nass, K., Andritschke, R., Schroter, C.-D., Krasniqi, F., Bott, M., Schmidt, K.E., Wang, X., Grotjohann, I., Holton, J.M., Barends, T.R.M., Neutze, R., Marchesini, S., Fromme, R., Schorb, S., Rupp, D., Adolph, M., Gorkhover, T., Andersson, I., Hirsemann, H., Potdevin, G., Graafsma, H., Nilsson, B., Spence, J.C.H.
Deposit date:2010-10-21
Release date:2011-02-02
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (8.984 Å)
Cite:Femtosecond X-ray protein nanocrystallography.
Nature, 470, 2011
2YOM
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SOLUTION NMR STRUCTURE OF THE C-TERMINAL EXTENSION OF TWO BACTERIAL LIGHT, OXYGEN, VOLTAGE (LOV) PHOTORECEPTOR PROTEINS FROM PSEUDOMONAS PUTIDA
Descriptor:SENSORY BOX PROTEIN
Authors:Rani, R., Lecher, J., Hartmann, R., Krauss, U., Jaeger, K., Willbold, D.
Deposit date:2012-10-25
Release date:2013-07-10
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:Conservation of Dark Recovery Kinetic Parameters and Structural Features in the Pseudomonadaceae "Short" Light, Oxygen, Voltage (Lov) Protein Family: Implications for the Design of Lov-Based Optogenetic Tools.
Biochemistry, 52, 2013
2YON
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SOLUTION NMR STRUCTURE OF THE C-TERMINAL EXTENSION OF TWO BACTERIAL LIGHT, OXYGEN, VOLTAGE (LOV) PHOTORECEPTOR PROTEINS FROM PSEUDOMONAS PUTIDA
Descriptor:SENSORY BOX PROTEIN
Authors:Rani, R., Hartmann, R., Lecher, J., Krauss, U., Jaeger, K., Willbold, D.
Deposit date:2012-10-25
Release date:2013-07-10
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:Conservation of Dark Recovery Kinetic Parameters and Structural Features in the Pseudomonadaceae "Short" Light, Oxygen, Voltage (Lov) Protein Family: Implications for the Design of Lov-Based Optogenetic Tools.
Biochemistry, 52, 2013
3HAF
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HUMAN PRION PROTEIN VARIANT V129 DOMAIN SWAPPED DIMER
Descriptor:Major prion protein, CADMIUM ION, CHLORIDE ION
Authors:Lee, S., Antony, L., Hartmann, R., Knaus, K.J., Surewicz, K., Surewicz, W.K., Yee, V.C.
Deposit date:2009-05-01
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HAK
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HUMAN PRION PROTEIN VARIANT V129
Descriptor:Major prion protein
Authors:Lee, S., Antony, L., Hartmann, R., Knaus, K.J., Surewicz, K., Surewicz, W.K., Yee, V.C.
Deposit date:2009-05-01
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HEQ
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HUMAN PRION PROTEIN VARIANT D178N WITH M129
Descriptor:Major prion protein, CADMIUM ION
Authors:Lee, S., Antony, L., Hartmann, R., Knaus, K.J., Surewicz, K., Surewicz, W.K., Yee, V.C.
Deposit date:2009-05-10
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HER
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HUMAN PRION PROTEIN VARIANT F198S WITH V129
Descriptor:Major prion protein, CADMIUM ION
Authors:Lee, S., Antony, L., Hartmann, R., Knaus, K.J., Surewicz, K., Surewicz, W.K., Yee, V.C.
Deposit date:2009-05-10
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HES
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HUMAN PRION PROTEIN VARIANT F198S WITH M129
Descriptor:Major prion protein, CADMIUM ION
Authors:Lee, S., Antony, L., Hartmann, R., Knaus, K.J., Surewicz, K., Surewicz, W.K., Yee, V.C.
Deposit date:2009-05-10
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HHC
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INTERFERON-LAMBDA IS FUNCTIONALLY AN INTERFERON BUT STRUCTURALLY RELATED TO THE IL-10 FAMILY
Descriptor:Interleukin-28B, IODIDE ION
Authors:Gad, H.H., Hamming, O.J., Hartmann, R.
Deposit date:2009-05-15
Release date:2009-07-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Interferon-{lambda} Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family
J.Biol.Chem., 284, 2009
3HJ5
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HUMAN PRION PROTEIN VARIANT V129 DOMAIN SWAPPED DIMER
Descriptor:Major prion protein
Authors:Lee, S., Antony, L., Hartmann, R., Knaus, K.J., Surewicz, K., Surewicz, W.K., Yee, V.C.
Deposit date:2009-05-20
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HJX
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HUMAN PRION PROTEIN VARIANT D178N WITH V129
Descriptor:Major prion protein, CADMIUM ION, CHLORIDE ION
Authors:Lee, S., Antony, L., Hartmann, R., Knaus, K.J., Surewicz, K., Surewicz, W.K., Yee, V.C.
Deposit date:2009-05-22
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3L9J
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SELECTION OF A NOVEL HIGHLY SPECIFIC TNFALPHA ANTAGONIST: INSIGHT FROM THE CRYSTAL STRUCTURE OF THE ANTAGONIST-TNFALPHA COMPLEX
Descriptor:TNFalpha, Tumor necrosis factor, soluble form, ...
Authors:Byla, P., Andersen, M.H., Thogersen, H.C., Gad, H.H., Hartmann, R.
Deposit date:2010-01-05
Release date:2010-02-23
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selection of a novel and highly specific TNF{alpha} antagonist: insight from the crystal structure of the antagonist-TNF{alpha} complex
J.Biol.Chem., 285, 2010
3PIV
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ZEBRAFISH INTERFERON 1
Descriptor:Interferon, NICKEL (II) ION
Authors:Hamming, O.J., Hartmann, R., Lutfalla, G., Levraud, J.-P.
Deposit date:2010-11-08
Release date:2011-07-20
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.086 Å)
Cite:Crystal Structure of Zebrafish Interferons I and II Reveals Conservation of Type I Interferon Structure in Vertebrates.
J.Virol., 85, 2011
3PIW
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ZEBRAFISH INTERFERON 2
Descriptor:Type I interferon 2
Authors:Hamming, O.J., Hartmann, R., Lutfalla, G., Levraud, J.-P.
Deposit date:2010-11-08
Release date:2011-07-20
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Crystal Structure of Zebrafish Interferons I and II Reveals Conservation of Type I Interferon Structure in Vertebrates.
J.Virol., 85, 2011
3TGX
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IL-21:IL21R COMPLEX
Descriptor:Interleukin-21 receptor, Interleukin-21, ALPHA-D-MANNOSE, ...
Authors:Hamming, O.J., Kang, L., Svenson, A., Karlsen, J.L., Rahbek-Nielsen, H., Paludan, S.R., Hjort, S.A., Bondensgaard, K., Hartmann, R.
Deposit date:2011-08-18
Release date:2012-02-15
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the interleukin 21 receptor bound to interleukin 21 reveals that a sugar chain interacting with the WSXWS motif is an integral part of the interleukin 21 receptor.
J.Biol.Chem., 2012
4NZD
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INTERLEUKIN 21 RECEPTOR
Descriptor:Interleukin-21 receptor, ALPHA-D-MANNOSE, ALPHA-L-FUCOSE, ...
Authors:Hamming, O.T., Kang, L., Siupka, P., Gad, H.H., Hartmann, R.
Deposit date:2013-12-12
Release date:2014-12-17
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Interleukin 21 receptor structure and function
To be Published
4O6K
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THE CRYSTAL STRUCTURE OF ZEBRAFISH IL-22
Descriptor:Interleukin 22
Authors:Siupka, P., Hamming, O.J., Fretaud, M., Luftalla, G., Levraud, J.P., Hartmann, R.
Deposit date:2013-12-21
Release date:2014-09-10
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of zebrafish IL-22 reveals an evolutionary, conserved structure highly similar to that of human IL-22.
Genes Immun., 15, 2014
4XQ7
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THE CRYSTAL STRUCTURE OF THE OAS-LIKE DOMAIN (OLD) OF HUMAN OASL
Descriptor:2'-5'-oligoadenylate synthase-like protein
Authors:Ibsen, M.S., Gad, H.H., Andersen, L.L., Hornung, V., Julkunen, I., Sarkar, S.N., Hartmann, R.
Deposit date:2015-01-19
Release date:2015-04-22
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling.
Nucleic Acids Res., 43, 2015
3MOR
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CRYSTAL STRUCTURE OF CATHEPSIN B FROM TRYPANOSOMA BRUCEI
Descriptor:Cathepsin B-like cysteine protease, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ...
Authors:Cupelli, K., Stehle, T.
Deposit date:2010-04-23
Release date:2011-11-02
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:In vivo protein crystallization opens new routes in structural biology.
Nat.Methods, 9, 2012
5J3W
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CRYSTAL STRUCTURES REVEAL SIGNALING STATES OF A SHORT BLUE LIGHT PHOTORECEPTOR PROTEIN PPSB1-LOV (DARK STATE)
Descriptor:Sensory box protein, FLAVIN MONONUCLEOTIDE
Authors:Granzin, J., Batra-Safferling, R.
Deposit date:2016-03-31
Release date:2016-06-22
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Signaling States of a Short Blue-Light Photoreceptor Protein PpSB1-LOV Revealed from Crystal Structures and Solution NMR Spectroscopy.
J.Mol.Biol., 428, 2016
5J4E
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CRYSTAL STRUCTURES REVEAL SIGNALING STATES OF A SHORT BLUE LIGHT PHOTORECEPTOR PROTEIN PPSB1-LOV (PHOTOEXCITED STATE)
Descriptor:Sensory box protein, FLAVIN MONONUCLEOTIDE
Authors:Granzin, J., Batra-Safferling, R.
Deposit date:2016-04-01
Release date:2016-06-22
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Signaling States of a Short Blue-Light Photoreceptor Protein PpSB1-LOV Revealed from Crystal Structures and Solution NMR Spectroscopy.
J.Mol.Biol., 428, 2016
2KLU
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NMR STRUCTURE OF THE TRANSMEMBRANE AND CYTOPLASMIC DOMAINS OF HUMAN CD4
Descriptor:T-cell surface glycoprotein CD4
Authors:Wittlich, M., Willbold, D.
Deposit date:2009-07-08
Release date:2009-10-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure of the transmembrane and cytoplasmic domains of human CD4 in micelles.
Biochim.Biophys.Acta, 1798, 2010
4CO7
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CRYSTAL STRUCTURE OF HUMAN GATE-16
Descriptor:GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 2
Authors:Weiergraeber, O.H., Ma, P., Willbold, D.
Deposit date:2014-01-27
Release date:2015-01-14
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational Polymorphism in Autophagy-Related Protein Gate-16.
Biochemistry, 54, 2015
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