Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1K5J
DownloadVisualize
BU of 1k5j by Molmil
The Crystal Structure of Nucleoplasmin-Core
Descriptor: Nucleoplasmin Core
Authors:Dutta, S, Akey, I.V, Dingwall, C, Hartman, K.L, Laue, T, Nolte, R.T, Head, J.F, Akey, C.W.
Deposit date:2001-10-10
Release date:2001-11-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of nucleoplasmin-core: implications for histone binding and nucleosome assembly.
Mol.Cell, 8, 2001
8DIQ
DownloadVisualize
BU of 8diq by Molmil
Tubulin-RB3_SLD-TTL in complex with SB226
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[2-(ethylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one, CALCIUM ION, ...
Authors:White, S.W, Yun, M.
Deposit date:2022-06-29
Release date:2023-01-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.395 Å)
Cite:SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis.
Cancer Lett., 555, 2022
7TTD
DownloadVisualize
BU of 7ttd by Molmil
Tubulin-RB3_SLD in complex with compound 12e
Descriptor: 7-methoxy-4-[2-(morpholin-4-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-3,4-dihydroquinoxalin-2(1H)-one, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:White, S.W, Yun, M.
Deposit date:2022-02-01
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo.
Acs Pharmacol Transl Sci, 6, 2023
7TTE
DownloadVisualize
BU of 7tte by Molmil
Tubulin-RB3_SLD in complex with compound 12j
Descriptor: 4-[2-(cyclopropylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:White, S.W, Yun, M.
Deposit date:2022-02-01
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo.
Acs Pharmacol Transl Sci, 6, 2023
7TTF
DownloadVisualize
BU of 7ttf by Molmil
Tubulin-RB3_SLD in complex with compound 12k
Descriptor: 7-methoxy-4-[2-(methylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-3,4-dihydroquinoxalin-2(1H)-one, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:White, S.W, Yun, M.
Deposit date:2022-02-01
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo.
Acs Pharmacol Transl Sci, 6, 2023
1WQ6
DownloadVisualize
BU of 1wq6 by Molmil
The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity
Descriptor: AML1-ETO
Authors:Liu, Y, Cheney, M.D, Chruszcz, M, Lukasik, S.M, Hartman, K.L, Laue, T.M, Dauter, Z, Minor, W, Speck, N.A, Bushweller, J.H.
Deposit date:2004-09-23
Release date:2005-10-04
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity
Cancer Cell, 9, 2006
2JHB
DownloadVisualize
BU of 2jhb by Molmil
CORE BINDING FACTOR BETA
Descriptor: PROTEIN (CORE BINDING FACTOR BETA)
Authors:Huang, X, Peng, J, Speck, N.A, Bushweller, J.H.
Deposit date:1999-03-17
Release date:1999-07-05
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of core binding factor beta and map of the CBF alpha binding site.
Nat.Struct.Biol., 6, 1999

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon