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5ABM
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SHEEP ALDEHYDE DEHYDROGENASE 1A1
Descriptor:RETINAL DEHYDROGENASE 1, [[(2R,3S,4R,5R)-5-[(3R)-3-aminocarbonyl-3,4-dihydro-2H-pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanidyl-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphate, MAGNESIUM ION
Authors:Koch, M.F., Harteis, S., Blank, I.D., Pestel, G., Tietze, L.F., Ochsenfeld, C., Schneider, S., Sieber, S.A.
Deposit date:2015-08-07
Release date:2015-09-16
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
Angew.Chem.Int.Ed.Engl., 54, 2015
5AC0
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OVIS ARIES ALDEHYDE DEHYDROGENASE 1A1 IN COMPLEX WITH A DUOCARMYCIN ANALOG
Descriptor:RETINAL DEHYDROGENASE 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1-[(1S)-1-methyl-5-oxidanyl-1,2-dihydrobenzo[e]indol-3-yl]hexan-1-one, ...
Authors:Koch, M.F., Harteis, S., Blank, I.D., Pestel, G., Tietze, L.F., Ochsenfeld, C., Schneider, S., Sieber, S.A.
Deposit date:2015-08-10
Release date:2015-08-26
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
Angew.Chem.Int.Ed.Engl., 54, 2015
5AC1
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SHEEP ALDEHYDE DEHYDROGENASE 1A1 WITH DUOCARMYCIN ANALOG INHIBITOR
Descriptor:RETINAL DEHYDROGENASE 1, 1-[(1S)-1-methyl-5-oxidanyl-1,2-dihydrobenzo[e]indol-3-yl]hexan-1-one, [[(2R,3S,4R,5R)-5-[(3R)-3-aminocarbonyl-3,4-dihydro-2H-pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanidyl-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphate, ...
Authors:Koch, M.F., Harteis, S., Blank, I.D., Pestel, G., Tietze, L.F., Ochsenfeld, C., Schneider, S., Sieber, S.A.
Deposit date:2015-08-11
Release date:2015-08-26
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
Angew.Chem.Int.Ed.Engl., 54, 2015
5AC2
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HUMAN ALDEHYDE DEHYDROGENASE 1A1 WITH DUOCARMYCIN ANALOG
Descriptor:RETINAL DEHYDROGENASE 1, 1-[(1S)-1-methyl-5-oxidanyl-1,2-dihydrobenzo[e]indol-3-yl]hexan-1-one, YTTERBIUM (III) ION, ...
Authors:Koch, M.F., Harteis, S., Blank, I.D., Pestel, G., Tietze, L.F., Ochsenfeld, C., Schneider, S., Sieber, S.A.
Deposit date:2015-08-11
Release date:2015-08-26
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
Angew.Chem.Int.Ed.Engl., 54, 2015
5OL1
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CRYSTAL STRUCTURE OF AN INACTIVATED SSP SICLOPPS INTEIN WITH A CAFHPQ EXTEIN
Descriptor:DNA polymerase III subunit alpha,DNA polymerase III subunit alpha, 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, ...
Authors:Kick, L.M., Schneider, S.
Deposit date:2017-07-26
Release date:2017-09-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Mechanistic Insights into Cyclic Peptide Generation by DnaE Split-Inteins through Quantitative and Structural Investigation.
Chembiochem, 18, 2017
5OL5
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CRYSTAL STRUCTURE OF AN INACTIVATED SSP SICLOPPS INTEIN WITH CFAHPQ EXTEIN
Descriptor:DNA polymerase III subunit alpha,DNA polymerase III subunit alpha, COBALT (II) ION, TETRAETHYLENE GLYCOL, ...
Authors:Kick, L.M., Schneider, S.
Deposit date:2017-07-26
Release date:2017-09-27
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.329 Å)
Cite:Mechanistic Insights into Cyclic Peptide Generation by DnaE Split-Inteins through Quantitative and Structural Investigation.
Chembiochem, 18, 2017
5OL6
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CRYSTAL STRUCTURE OF AN INACTIVATED NPU SICLOPPS INTEIN WITH CAFHPQ EXTEIN
Descriptor:Nucleic acid binding, OB-fold, tRNA/helicase-type,DNA-directed DNA polymerase
Authors:Kick, L.M., Schneider, S.
Deposit date:2017-07-26
Release date:2017-09-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanistic Insights into Cyclic Peptide Generation by DnaE Split-Inteins through Quantitative and Structural Investigation.
Chembiochem, 18, 2017
5OL7
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CRYSTAL STRUCTURE OF AN INACTIVATED NPU SICLOPPS INTEIN WITH CFAHPQ EXTEIN
Descriptor:DNA-directed DNA polymerase,DNA-directed DNA polymerase, CALCIUM ION, COBALT (II) ION
Authors:Kick, L.M., Schneider, S.
Deposit date:2017-07-26
Release date:2017-09-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mechanistic Insights into Cyclic Peptide Generation by DnaE Split-Inteins through Quantitative and Structural Investigation.
Chembiochem, 18, 2017