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1KQR
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CRYSTAL STRUCTURE OF THE RHESUS ROTAVIRUS VP4 SIALIC ACID BINDING DOMAIN IN COMPLEX WITH 2-O-METHYL-ALPHA-D-N-ACETYL NEURAMINIC ACID
分子名称:VP4, SULFATE ION, 2-O-METHYL-5-N-ACETYL-ALPHA-D- NEURAMINIC ACID, ...
著者Dormitzer, P.R., Sun, Z.-Y.J., Wagner, G., Harrison, S.C.
登録日2002-01-07
公開日2002-03-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The Rhesus Rotavirus VP4 Sialic Acid Binding Domain has a Galectin Fold with a Novel Carbohydrate Binding Site
Embo J., 21, 2002
1FMK
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CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC
分子名称:TYROSINE-PROTEIN KINASE SRC
著者Xu, W., Harrison, S.C., Eck, M.J.
登録日1997-01-24
公開日1997-08-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Three-dimensional structure of the tyrosine kinase c-Src.
Nature, 385, 1997
2SRC
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CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC, IN COMPLEX WITH AMP-PNP
分子名称:TYROSINE-PROTEIN KINASE SRC, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Xu, W., Doshi, A., Lei, M., Eck, M.J., Harrison, S.C.
登録日1998-12-29
公開日1999-07-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structures of c-Src reveal features of its autoinhibitory mechanism.
Mol.Cell, 3, 1999
4Y95
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CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF BRUTON'S TYROSINE KINASE WITH MUTATIONS IN THE ACTIVATION LOOP
分子名称:Non-specific protein-tyrosine kinase, 4-tert-butyl-N-[2-methyl-3-(4-methyl-6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide, GLYCEROL, ...
著者Wang, Q., Rosen, C.E., Kuriyan, J.
登録日2015-02-16
公開日2015-03-18
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate.
Elife, 4, 2015
5W6C
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UCA FAB (UNBOUND) FROM 6649 LINEAGE
分子名称:UCA Fab heavy chain, UCA Fab light chain
著者Raymond, D.D., Harrison, S.C.
登録日2017-06-16
公開日2017-12-13
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (1.634 Å)
主引用文献Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4Y93
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CRYSTAL STRUCTURE OF THE PH-TH-KINASE CONSTRUCT OF BRUTON'S TYROSINE KINASE (BTK)
分子名称:Non-specific protein-tyrosine kinase,Non-specific protein-tyrosine kinase, ZINC ION, 4-tert-butyl-N-[2-methyl-3-(4-methyl-6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide, ...
著者Wang, Q., Kuriyan, J.
登録日2015-02-16
公開日2015-03-18
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.695 Å)
主引用文献Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate.
Elife, 4, 2015
1MOF
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COAT PROTEIN
分子名称:MOLONEY MURINE LEUKEMIA VIRUS P15, CHLORIDE ION
著者Fass, D., Harrison, S.C., Kim, P.S.
登録日1996-04-02
公開日1996-10-14
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Retrovirus envelope domain at 1.7 angstrom resolution.
Nat.Struct.Biol., 3, 1996
5IBU
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6652 FAB (UNBOUND)
分子名称:6652 Light Chain, 6652 Heavy Chain
著者Raymond, D.D., Harrison, S.C.
登録日2016-02-22
公開日2016-11-09
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
5UKN
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STRUCTURE OF UNLIGANDED ANTI-GP120 CD4BS ANTIBODY DH522UCA FAB
分子名称:DH522UCA Fab fragment heavy chain, DH522UCA Fab fragment light chain, CHLORIDE ION
著者Nicely, N.I.
登録日2017-01-23
公開日2017-12-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.
Nat Commun, 8, 2017
5T6J
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STRUCTURE OF THE MIND COMPLEX SHOWS A REGULATORY FOCUS OF YEAST KINETOCHORE ASSEMBLY
分子名称:Kinetochore protein SPC24, Kinetochore protein SPC25, Kinetochore-associated protein DSN1
著者Valverde, R., Jenni, S., Dimitrova, Y., Khin, Y., Harrison, S.C.
登録日2016-09-01
公開日2016-11-09
最終更新日2016-12-21
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly.
Cell, 167, 2016
1FN9
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CRYSTAL STRUCTURE OF THE REOVIRUS OUTER CAPSID PROTEIN SIGMA 3
分子名称:OUTER-CAPSID PROTEIN SIGMA 3, ZINC ION
著者Olland, A.M., Jane-Valbuena, J., Schiff, L.A., Nibert, M.L., Harrison, S.C.
登録日2000-08-21
公開日2001-03-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the reovirus outer capsid and dsRNA-binding protein sigma3 at 1.8 A resolution.
EMBO J., 20, 2001
1LCJ
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SH2 (SRC HOMOLOGY-2) DOMAIN OF HUMAN P56-LCK TYROSINE KINASE COMPLEXED WITH THE 11 RESIDUE PHOSPHOTYROSYL PEPTIDE EPQPYEEIPIYL
分子名称:P56==LCK== TYROSINE KINASE, PHOSPHOPEPTIDE EPQ(PHOSPHO)YEEIPIYL
著者Eck, M., Harrison, S.
登録日1994-12-12
公開日1995-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck.
Nature, 362, 1993
1LMB
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REFINED 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR-OPERATOR COMPLEX
分子名称:DNA (5'-D(*AP*AP*TP*AP*CP*CP*AP*CP*TP*GP*GP*CP*GP*GP*TP*GP*A P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*TP*CP*AP*CP*CP*GP*CP*CP*AP*GP*TP*GP*G P*TP*AP*T)-3'), PROTEIN (LAMBDA REPRESSOR)
著者Beamer, L.J., Pabo, C.O.
登録日1991-11-05
公開日1991-11-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Refined 1.8 A crystal structure of the lambda repressor-operator complex.
J.Mol.Biol., 227, 1992
1YHV
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CRYSTAL STRUCTURE OF PAK1 KINASE DOMAIN WITH TWO POINT MUTATIONS (K299R, T423E)
分子名称:Serine/threonine-protein kinase PAK 1
著者Lei, M., Robinson, M.A., Harrison, S.C.
登録日2005-01-10
公開日2005-05-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Active Conformation of the PAK1 Kinase Domain
Structure, 13, 2005
1YHW
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CRYSTAL STRUCTURE OF PAK1 KINASE DOMAIN WITH ONE POINT MUTATIONS (K299R)
分子名称:Serine/threonine-protein kinase PAK 1
著者Lei, M., Robinson, M.A., Harrison, S.C.
登録日2005-01-10
公開日2005-05-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Active Conformation of the PAK1 Kinase Domain
Structure, 13, 2005
2IGP
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CRYSTAL STRUCTURE OF HEC1 CH DOMAIN
分子名称:Retinoblastoma-associated protein HEC, BETA-MERCAPTOETHANOL
著者Wei, R.R., Harrison, S.C.
登録日2006-09-22
公開日2007-01-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment.
Nat.Struct.Mol.Biol., 14, 2007
2SPC
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CRYSTAL STRUCTURE OF THE REPETITIVE SEGMENTS OF SPECTRIN
分子名称:SPECTRIN
著者Yan, Y., Winograd, E., Viel, A., Cronin, T., Harrison, S.C., Branton, D.
登録日1994-03-01
公開日1994-05-31
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the repetitive segments of spectrin.
Science, 262, 1993
5EN2
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MOLECULAR BASIS FOR ANTIBODY-MEDIATED NEUTRALIZATION OF NEW WORLD HEMORRHAGIC FEVER MAMMARENAVIRUSES
分子名称:GD01 heavy chain, GD01 light chain, Pre-glycoprotein polyprotein GP complex, ...
著者Mahmutovic, S., Clark, L., Levis, S., Briggiler, A., Enria, D., Harrison, S.C., Abraham, J.
登録日2015-11-09
公開日2015-12-30
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (1.821 Å)
主引用文献Molecular Basis for Antibody-Mediated Neutralization of New World Hemorrhagic Fever Mammarenaviruses.
Cell Host Microbe, 18, 2015
5TPP
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CRYSTAL STRUCTURE OF DH270.5 (UNLIGANDED) FROM THE DH270 BROADLY NEUTRALIZING N332-GLYCAN DEPENDENT LINEAGE
分子名称:DH270.5 Fab heavy chain, DH270.5 Fab light chain, SODIUM ION, ...
著者Fera, D., Harrison, S.C.
登録日2016-10-20
公開日2017-03-15
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
2IUG
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CRYSTAL STRUCTURE OF THE PI3-KINASE P85 N-TERMINAL SH2 DOMAIN
分子名称:PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT
著者Nolte, R.T., Eck, M.J., Schlessinger, J., Shoelson, S.E., Harrison, S.C.
登録日2006-06-03
公開日2006-06-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes
Nat.Struct.Biol., 3, 1996
5W0D
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INFERRED PRECURSOR (UCA) OF THE HUMAN ANTIBODY LINEAGE K03.12 IN COMPLEX WITH INFLUENZA HEMAGGLUTININ H1 SOLOMON ISLANDS/03/2006
分子名称:Hemagglutinin HA1, Lineage K03.12 UCA antibody heavy chain, Lineage K03.12 UCA antibody light chain, ...
著者McCarthy, K.R., Harrison, S.C.
登録日2017-05-30
公開日2018-02-14
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires.
Immunity, 48, 2018
1SVB
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ENVELOPE GLYCOPROTEIN FROM TICK-BORNE ENCEPHALITIS VIRUS
分子名称:TICK-BORNE ENCEPHALITIS VIRUS GLYCOPROTEIN, N-ACETYL-D-GLUCOSAMINE
著者Rey, F.A., Harrison, S.C.
登録日1995-11-27
公開日1996-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution.
Nature, 375, 1995
1VPS
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POLYOMAVIRUS VP1 PENTAMER COMPLEXED WITH A DISIALYLATED HEXASACCHARIDE
分子名称:POLYOMAVIRUS VP1 PENTAMER, O-SIALIC ACID, BETA-D-GALACTOSE, ...
著者Stehle, T., Harrison, S.C.
登録日1997-03-07
公開日1997-05-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-resolution structure of a polyomavirus VP1-oligosaccharide complex: implications for assembly and receptor binding.
Embo J., 16, 1997
1XIW
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CRYSTAL STRUCTURE OF HUMAN CD3-E/D DIMER IN COMPLEX WITH A UCHT1 SINGLE-CHAIN ANTIBODY FRAGMENT
分子名称:T-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 delta chain, immunoglobulin light chain variable region, ...
著者Arnett, K.L., Harrison, S.C., Wiley, D.C.
登録日2004-09-22
公開日2004-11-16
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment.
Proc.Natl.Acad.Sci.USA, 101, 2004
2B6O
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ELECTRON CRYSTALLOGRAPHIC STRUCTURE OF LENS AQUAPORIN-0 (AQP0) (LENS MIP) AT 1.9A RESOLUTION, IN A CLOSED PORE STATE
分子名称:Lens fiber major intrinsic protein, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE
著者Gonen, T., Cheng, Y., Sliz, P., Hiroaki, Y., Fujiyoshi, Y., Harrison, S.C., Walz, T.
登録日2005-10-03
公開日2005-12-06
最終更新日2018-07-18
実験手法ELECTRON CRYSTALLOGRAPHY (1.9 Å)
主引用文献Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005