Author results

1QIV
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CALMODULIN COMPLEXED WITH N-(3,3,-DIPHENYLPROPYL)-N'-[1-R-(3,4-BIS-BUTOXYPHENYL)-ETHYL]-PROPYLENEDIAMINE (DPD), 1:2 COMPLEX
Descriptor:CALMODULIN, CALCIUM ION, N-(3,3,-DIPHENYLPROPYL)-N'-[1-R-(2 3,4-BIS-BUTOXYPHENYL)-ETHYL]-PROPYLENEDIAMINE
Authors:Harmat, V., Bocskei, Z.S., Vertessy, B.G., Naray-Szabo, G., Ovadi, J.
Deposit date:1999-06-17
Release date:2000-03-28
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:A New Potent Calmodulin Antagonist with Arylalkylamine Structure: Crystallographic, Spectroscopic and Functional Studies
J.Mol.Biol., 297, 2000
1Q3X
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CRYSTAL STRUCTURE OF THE CATALYTIC REGION OF HUMAN MASP-2
Descriptor:Mannan-binding lectin serine protease 2, SODIUM ION, GLYCEROL
Authors:Harmat, V., Gal, P., Kardos, J., Szilagyi, K., Ambrus, G., Naray-Szabo, G., Zavodszky, P.
Deposit date:2003-08-01
Release date:2004-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions
J.Mol.Biol., 342, 2004
1QIW
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CALMODULIN COMPLEXED WITH N-(3,3,-DIPHENYLPROPYL)-N'-[1-R-(3,4-BIS-BUTOXYPHENYL)-ETHYL]-PROPYLENEDIAMINE (DPD)
Descriptor:CALMODULIN, CALCIUM ION, N-(3,3,-DIPHENYLPROPYL)-N'-[1-R-(2 3,4-BIS-BUTOXYPHENYL)-ETHYL]-PROPYLENEDIAMINE
Authors:Harmat, V., Bocskei, Z.S., Vertessy, B.G., Ovadi, J., Naray-Szabo, G.
Deposit date:1999-06-17
Release date:2000-03-28
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A New Potent Calmodulin Antagonist with Arylalkylamine Structure: Crystallographic, Spectroscopic and Functional Studies
J.Mol.Biol., 297, 2000
3O4G
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STRUCTURE AND CATALYSIS OF ACYLAMINOACYL PEPTIDASE
Descriptor:Acylamino-acid-releasing enzyme, GLYCEROL
Authors:Harmat, V., Domokos, K., Menyhard, D.K., Pallo, A., Szeltner, Z., Szamosi, I., Beke-Somfai, T., Naray-Szabo, G., Polgar, L.
Deposit date:2010-07-27
Release date:2010-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASE.
J.Biol.Chem., 286, 2011
3O4H
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STRUCTURE AND CATALYSIS OF ACYLAMINOACYL PEPTIDASE
Descriptor:Acylamino-acid-releasing enzyme, GLYCEROL, SODIUM ION
Authors:Harmat, V., Domokos, K., Menyhard, D.K., Pallo, A., Szeltner, Z., Szamosi, I., Beke-Somfai, T., Naray-Szabo, G., Polgar, L.
Deposit date:2010-07-27
Release date:2010-11-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASE.
J.Biol.Chem., 286, 2011
3O4I
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STRUCTURE AND CATALYSIS OF ACYLAMINOACYL PEPTIDASE
Descriptor:Acylamino-acid-releasing enzyme, GLYCEROL, CHLORIDE ION
Authors:Harmat, V., Domokos, K., Menyhard, D.K., Pallo, A., Szeltner, Z., Szamosi, I., Beke-Somfai, T., Naray-Szabo, G., Polgar, L.
Deposit date:2010-07-27
Release date:2010-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASE.
J.Biol.Chem., 286, 2011
3O4J
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STRUCTURE AND CATALYSIS OF ACYLAMINOACYL PEPTIDASE
Descriptor:Acylamino-acid-releasing enzyme, GLYCEROL, CHLORIDE ION, ...
Authors:Harmat, V., Domokos, K., Menyhard, D.K., Pallo, A., Szeltner, Z., Szamosi, I., Beke-Somfai, T., Naray-Szabo, G., Polgar, L.
Deposit date:2010-07-27
Release date:2010-11-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASE.
J.Biol.Chem., 286, 2011
2OAY
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CRYSTAL STRUCTURE OF LATENT HUMAN C1-INHIBITOR
Descriptor:Plasma protease C1 inhibitor, N-ACETYL-D-GLUCOSAMINE, GLYCEROL
Authors:Harmat, V., Beinrohr, L., Gal, P., Dobo, J.
Deposit date:2006-12-18
Release date:2007-05-01
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:C1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational disease
J.Biol.Chem., 282, 2007
2QR5
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AEROPYRUM PERNIX ACYLAMINOACYL PEPTIDASE, H367A MUTANT
Descriptor:Acylamino-acid-releasing enzyme
Authors:Harmat, V., Pallo, A., Kiss, A.L., Polgar, L.
Deposit date:2007-07-27
Release date:2008-05-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and kinetic contributions of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase
J.Struct.Biol., 162, 2008
3GOV
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CRYSTAL STRUCTURE OF THE CATALYTIC REGION OF HUMAN MASP-1
Descriptor:MASP-1, GLYCEROL
Authors:Harmat, V., Dobo, J., Beinrohr, L., Sebestyen, E., Zavodszky, P., Gal, P.
Deposit date:2009-03-20
Release date:2009-06-09
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity.
J.Immunol., 183, 2009
4IGD
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CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC REGION OF HUMAN MASP-1
Descriptor:Mannan-binding lectin serine protease 1, GLYCEROL
Authors:Harmat, V., Megyeri, M., Vegh, A., Dobo, J.
Deposit date:2012-12-17
Release date:2013-02-13
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway
J.Biol.Chem., 288, 2013
1ZJK
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CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC REGION OF HUMAN MASP-2
Descriptor:Mannan-binding lectin serine protease 2
Authors:Gal, P., Harmat, V., Kocsis, A., Bian, T., Barna, L., Ambrus, G., Vegh, B., Balczer, J., Sim, R.B., Naray-Szabo, G., Zavodszky, P.
Deposit date:2005-04-29
Release date:2005-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:A True Autoactivating Enzyme: Structural insight into mannose-binding lectin-associated serine protease-2 activations
J.Biol.Chem., 280, 2005
2F91
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1.2A RESOLUTION STRUCTURE OF A CRAYFISH TRYPSIN COMPLEXED WITH A PEPTIDE INHIBITOR, SGTI
Descriptor:hepatopancreas trypsin, Serine protease inhibitor I/II, CADMIUM ION, ...
Authors:Fodor, K., Harmat, V., Hetenyi, C., Kardos, J., Antal, J., Perczel, A., Patthy, A., Katona, G., Graf, L.
Deposit date:2005-12-05
Release date:2006-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis.
Biochemistry, 45, 2006
4HXE
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PYROCOCCUS HORIKOSHII ACYLAMINOACYL PEPTIDASE (UNCOMPLEXED)
Descriptor:Putative uncharacterized protein PH0594, MAGNESIUM ION, HEXANE-1,6-DIOL
Authors:Tichy-Racs, E., Hornung, B., Radi, K., Menyhard, D.K., Kiss-Szeman, A., Szeltner, Z., Domokos, K., Szamosi, I., Naray-Szabo, G., Polgar, L., Harmat, V.
Deposit date:2012-11-09
Release date:2013-05-08
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATION.
J.Biol.Chem., 288, 2013
4HXF
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ACYLAMINOACYL PEPTIDASE IN COMPLEX WITH Z-GLY-GLY-PHE-CHLOROMETHYL KETONE
Descriptor:Putative uncharacterized protein PH0594, N-[(benzyloxy)carbonyl]glycyl-N-[(2S,3R)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]glycinamide, MAGNESIUM ION, ...
Authors:Kiss-Szeman, A., Menyhard, D.K., Tichy-Racs, E., Hornung, B., Radi, K., Szeltner, Z., Domokos, K., Szamosi, I., Naray-Szabo, G., Polgar, L., Harmat, V.
Deposit date:2012-11-09
Release date:2013-05-08
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATION.
J.Biol.Chem., 288, 2013
4HXG
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PYROCOCCUS HORIKOSHII ACYLAMINOACYL PEPTIDASE (ORTHORHOMBIC CRYSTAL FORM)
Descriptor:Putative uncharacterized protein PH0594, HEXANE-1,6-DIOL, MAGNESIUM ION, ...
Authors:Kiss-Szeman, A., Menyhard, D.K., Tichy-Racs, E., Hornung, B., Radi, K., Szeltner, Z., Domokos, K., Szamosi, I., Naray-Szabo, G., Polgar, L., Harmat, V.
Deposit date:2012-11-09
Release date:2013-05-08
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATION.
J.Biol.Chem., 288, 2013
4GV8
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DUTPASE FROM PHAGE PHI11 OF S.AUREUS: VISUALIZATION OF THE SPECIES-SPECIFIC INSERT
Descriptor:DUTPase, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION
Authors:Leveles, I., Harmat, V., Nemeth, V., Bendes, A., Szabo, J., Kadar, V., Zagyva, I., Rona, G., Toth, J., Vertessy, B.G.
Deposit date:2012-08-30
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and enzymatic mechanism of a moonlighting dUTPase
Acta Crystallogr.,Sect.D, 69, 2013
1XA5
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STRUCTURE OF CALMODULIN IN COMPLEX WITH KAR-2, A BIS-INDOL ALKALOID
Descriptor:Calmodulin, CALCIUM ION, 3"-(BETA-CHLOROETHYL)-2",4"-DIOXO-3, ...
Authors:Horvath, I., Harmat, V., Hlavanda, E., Naray-Szabo, G., Ovadi, J.
Deposit date:2004-08-25
Release date:2004-12-21
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The structure of the complex of calmodulin with KAR-2: a novel mode of binding explains the unique pharmacology of the drug
J.Biol.Chem., 280, 2005
1A29
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CALMODULIN COMPLEXED WITH TRIFLUOPERAZINE (1:2 COMPLEX)
Descriptor:CALMODULIN, CALCIUM ION, 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE
Authors:Bocskei, Zs., Harmat, V., Vertessy, B.G., Ovadi, J., Naray-Szabo, G.
Deposit date:1998-01-19
Release date:1998-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Simultaneous binding of drugs with different chemical structures to Ca2+-calmodulin: crystallographic and spectroscopic studies.
Biochemistry, 37, 1998
2BL0
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PHYSARUM POLYCEPHALUM MYOSIN II REGULATORY DOMAIN
Descriptor:MAJOR PLASMODIAL MYOSIN HEAVY CHAIN, MYOSIN REGULATORY LIGHT CHAIN, CALCIUM ION
Authors:Debreczeni, J.E., Farkas, L., Harmat, V., Nyitray, L.
Deposit date:2005-02-23
Release date:2005-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Evidence for Non-Canonical Binding of Ca2+ to a Canonical EF-Hand of a Conventional Myosin.
J.Biol.Chem., 280, 2005
2HU5
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BINDING OF INHIBITORS BY ACYLAMINOACYL-PEPTIDASE
Descriptor:Acylamino-acid-releasing enzyme, GLYCINE, PHENYLALANINE, ...
Authors:Kiss, A.L., Hornung, B., Radi, K., Gengeliczki, Z., Sztaray, B., Harmat, V., Polgar, L.
Deposit date:2006-07-26
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Acylaminoacyl Peptidase from Aeropyrum pernix K1 Thought to Be an Exopeptidase Displays Endopeptidase Activity
J.Mol.Biol., 368, 2007
2HU7
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BINDING OF INHIBITORS BY ACYLAMINOACYL PEPTIDASE
Descriptor:Acylamino-acid-releasing enzyme, ACETYL GROUP, PHENYLALANINE, ...
Authors:Kiss, A.L., Hornung, B., Radi, K., Gengeliczki, Z., Sztaray, B., Harmat, V., Polgar, L.
Deposit date:2006-07-26
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The Acylaminoacyl Peptidase from Aeropyrum pernix K1 Thought to Be an Exopeptidase Displays Endopeptidase Activity
J.Mol.Biol., 368, 2007
2HU8
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BINDING OF INHIBITORS BY ACYLAMINOACYL PEPTIDASE
Descriptor:Acylamino-acid-releasing enzyme, 2-AMINOBENZOIC ACID, GLYCINE, ...
Authors:Kiss, A.L., Hornung, B., Radi, K., Gengeliczki, Z., Sztaray, B., Harmat, V., Polgar, L.
Deposit date:2006-07-26
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Acylaminoacyl Peptidase from Aeropyrum pernix K1 Thought to Be an Exopeptidase Displays Endopeptidase Activity
J.Mol.Biol., 368, 2007
2QY0
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ACTIVE DIMERIC STRUCTURE OF THE CATALYTIC DOMAIN OF C1R REVEALS ENZYME-PRODUCT LIKE CONTACTS
Descriptor:Complement C1r subcomponent, GLYCEROL
Authors:Kardos, J., Harmat, V., Pallo, A., Barabas, O., Szilagyi, K., Graf, L., Naray-Szabo, G., Goto, Y., Zavodszky, P., Gal, P.
Deposit date:2007-08-13
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r.
Mol.Immunol., 45, 2008
2XQQ
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HUMAN DYNEIN LIGHT CHAIN (DYNLL2) IN COMPLEX WITH AN IN VITRO EVOLVED PEPTIDE (AC-SRGTQTE).
Descriptor:DYNEIN LIGHT CHAIN 2, CYTOPLASMIC, SAC-ARG-GLY-THR-GLN-THR-GLU, ...
Authors:Rapali, P., Radnai, L., Suveges, D., Hetenyi, C., Harmat, V., Tolgyesi, F., Wahlgren, W.Y., Katona, G., Nyitray, L., Pal, G.
Deposit date:2010-09-07
Release date:2011-05-04
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Directed Evolution Reveals the Binding Motif Preference of the Lc8/Dynll Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome
Plos One, 6, 2011
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