Author results

6J7V
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STRUCTURE OF HRPV6 VP5 FITTED IN THE CRYOEM DENSITY OF THE SPIKE
Descriptor:VP5
Authors:El Omari, K., Li, S., Huiskonen, J.T., Stuart, D.I.
Deposit date:2019-01-18
Release date:2019-03-06
Method:ELECTRON MICROSCOPY (16 Å)
Cite:The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins.
Nat Commun, 10, 2019
6QGI
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CRYSTAL STRUCTURE OF VP5 FROM HALOARCHAEAL PLEOMORPHIC VIRUS 2
Descriptor:VP5, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION
Authors:El Omari, K., Walter, T.S., Harlos, K., Grimes, J.M., Stuart, D.I., Roine, E.
Deposit date:2019-01-11
Release date:2019-02-27
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins.
Nat Commun, 10, 2019
6QGL
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CRYSTAL STRUCTURE OF VP5 FROM HALOARCHAEAL PLEOMORPHIC VIRUS 6
Descriptor:VP5, BROMIDE ION
Authors:El Omari, K., Walter, T.S., Harlos, K., Grimes, J.M., Stuart, D.I., Roine, E.
Deposit date:2019-01-11
Release date:2019-02-27
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins.
Nat Commun, 10, 2019
6I9I
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RIFT VALLEY FEVER VIRUS GN IN COMPLEX WITH A NEUTRALIZING ANTIBODY FRAGMENT
Descriptor:RV-Gn1 Heavy chain, RV-Gn1 Light chain, Glycoprotein
Authors:Allen, E.R., Bowden, T.A.
Deposit date:2018-11-23
Release date:2018-12-26
Last modified:2019-01-09
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus.
Cell Rep, 25, 2018
6GL1
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HLA-E*01:03 IN COMPLEX WITH THE HIV EPITOPE, RL9HIV
Descriptor:MHC class I antigen, Beta-2-microglobulin, ARG-MET-TYR-SER-PRO-THR-SER-ILE-LEU, ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-22
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.623 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GHN
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HLA-E*01:03 IN COMPLEX WITH THE MTB44 PEPTIDE VARIANT: MTB44*P9-PHE.
Descriptor:HLA class I histocompatibility antigen, E alpha chain variant, Beta-2-microglobulin, ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-08
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.542 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GH1
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HLA-E*01:03 IN COMPLEX WITH MTB44
Descriptor:MHC class I antigen, Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-04
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GH4
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HLA-E*01:03 IN COMPLEX WITH THE MTB44 PEPTIDE VARIANT: MTB44*P2-GLN.
Descriptor:MHC class I antigen, Beta-2-microglobulin, ARG-GLN-PRO-ALA-LYS-ALA-PRO-LEU-LEU, ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-04
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GGM
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HLA-E*01:03 IN COMPLEX WITH THE MTB44 PEPTIDE VARIANT: MTB44*P2-PHE.
Descriptor:MHC class I antigen, Beta-2-microglobulin, Mtb44*P2-Phe peptide variant (ARG-PHE-PRO-ALA-LYS-ALA-PRO-LEU-LEU), ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-03
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.734 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GBI
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WNT SIGNALLING
Descriptor:Ly6/PLAUR domain-containing protein 6, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ...
Authors:Zhao, Y., Jones, E.Y.
Deposit date:2018-04-14
Release date:2018-08-15
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structure of the Wnt signaling enhancer LYPD6 and its interactions with the Wnt coreceptor LRP6.
FEBS Lett., 592, 2018
5ZKE
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PLASMODIUM VIVAX P43 IN SPACE GROUP P212121
Descriptor:Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein p43
Authors:Gupta, S., Sharma, M., Harlos, K., Manickam, Y., Sharma, A.
Deposit date:2018-03-23
Release date:2019-04-24
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Structural analysis of aminoacyl-tRNA synthetase-interacting multifunctional proteins from plasmodium species
To Be Published
5ZKF
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PLASMODIUM VIVAX P43 IN SPACE GROUP P21
Descriptor:Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein p43
Authors:Gupta, S., Sharma, M., Harlos, K., Manickam, Y., Sharma, A.
Deposit date:2018-03-23
Release date:2019-04-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural analysis of aminoacyl-tRNA synthetase-interacting multifunctional proteins from plasmodium species
To Be Published
5ZKG
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CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF PLASMODIUM VIVAX P43
Descriptor:Aminoacyl-tRna synthetase-interacting multifunctional protein P43
Authors:Gupta, S., Sharma, M., Manickam, Y., Sharma, A.
Deposit date:2018-03-23
Release date:2019-04-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural analysis of aminoacyl-tRNA synthetase-interacting multifunctional proteins from plasmodium species
To Be Published
5ZH2
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-5
Descriptor:Lysine-tRNA ligase, LYSINE, (3R)-6,8-dihydroxy-3-{[(2R,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, ...
Authors:Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
Deposit date:2018-03-11
Release date:2018-06-27
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5ZH3
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-6
Descriptor:Lysine-tRNA ligase, LYSINE, (3S)-6,8-dihydroxy-3-{[(2R,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one
Authors:Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
Deposit date:2018-03-11
Release date:2018-06-27
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5ZH4
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-7
Descriptor:Lysine-tRNA ligase, LYSINE, (3R)-6,8-dihydroxy-3-{[(2S,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, ...
Authors:Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
Deposit date:2018-03-11
Release date:2018-06-27
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5ZH5
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-2
Descriptor:Lysine--tRNA ligase, LYSINE, (3S)-6,8-dihydroxy-3-{[(2R,6S)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, ...
Authors:Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
Deposit date:2018-03-11
Release date:2018-06-27
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5Z79
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CRYSTAL STRUCTURE ANALYSIS OF THE HPPK-DHPS IN COMPLEX WITH SUBSTRATES
Descriptor:Hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase, putative, 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE, ...
Authors:Manickam, Y., Karl, H., Sharma, A.
Deposit date:2018-01-27
Release date:2018-08-29
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-dihydropteroate synthase fromPlasmodium vivaxsheds light on drug resistance
J. Biol. Chem., 293, 2018
6FKK
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DROSOPHILA SEMAPHORIN 1B, EXTRACELLULAR DOMAINS 1-2
Descriptor:MIP07328p, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Rozbesky, D., Harlos, K., Jones, E.Y.
Deposit date:2018-01-24
Release date:2019-02-06
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural basis of semaphorin-plexin cis interaction
To Be Published
6FKM
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DROSOPHILA PLEXIN A IN COMPLEX WITH SEMAPHORIN 1B
Descriptor:Plexin A, isoform A, MIP07328p, ...
Authors:Rozbesky, D., Harlos, K., Jones, E.Y.
Deposit date:2018-01-24
Release date:2019-02-06
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Structural basis of semaphorin-plexin cis interaction
To Be published
6FKN
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DROSOPHILA PLEXIN A IN COMPLEX WITH SEMAPHORIN 1B
Descriptor:Plexin A, isoform A, MIP07328p, ...
Authors:Rozbesky, D., Harlos, K., Jones, E.Y.
Deposit date:2018-01-24
Release date:2019-02-06
Method:X-RAY DIFFRACTION (4.801 Å)
Cite:Structural basis of semaphorin-plexin cis interaction
To Be Published
6F9B
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ASYMMETRIC UNIT OF RIFT VALLEY FEVER VIRUS GLYCOPROTEIN SHELL
Descriptor:Glycoprotein
Authors:Halldorsson, S., Bowden, T.A., Huiskonen, J.T.
Deposit date:2017-12-14
Release date:2018-01-31
Last modified:2018-02-07
Method:ELECTRON MICROSCOPY (13.3 Å)
Cite:Shielding and activation of a viral membrane fusion protein.
Nat Commun, 9, 2018
6F9C
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MODEL OF THE RIFT VALLEY FEVER VIRUS GLYCOPROTEIN HEXAMER TYPE 1
Descriptor:Glycoprotein
Authors:Halldorsson, S., Bowden, T.A., Huiskonen, J.T.
Deposit date:2017-12-14
Release date:2018-01-31
Last modified:2018-02-07
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Shielding and activation of a viral membrane fusion protein.
Nat Commun, 9, 2018
6F9D
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MODEL OF THE RIFT VALLEY FEVER VIRUS GLYCOPROTEIN HEXAMER TYPE 2
Descriptor:Glycoprotein
Authors:Halldorsson, S., Bowden, T.A., Huiskonen, J.T.
Deposit date:2017-12-14
Release date:2018-01-31
Last modified:2018-02-07
Method:ELECTRON MICROSCOPY (13.3 Å)
Cite:Shielding and activation of a viral membrane fusion protein.
Nat Commun, 9, 2018
6F9E
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MODEL OF THE RIFT VALLEY FEVER VIRUS GLYCOPROTEIN HEXAMER TYPE 3
Descriptor:Glycoprotein
Authors:Halldorsson, S., Bowden, T.A., Huiskonen, J.T.
Deposit date:2017-12-14
Release date:2018-01-31
Last modified:2018-03-07
Method:ELECTRON MICROSCOPY (13.3 Å)
Cite:Shielding and activation of a viral membrane fusion protein.
Nat Commun, 9, 2018