Author results

1B2T
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SOLUTION STRUCTURE OF THE CX3C CHEMOKINE DOMAIN OF FRACTALKINE
Descriptor:PROTEIN (FRACTALKINE)
Authors:Handel, T.M., Mizoue, L.S., Bazan, J.F., Johnson, E.C.
Deposit date:1998-12-01
Release date:1999-04-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the CX3C chemokine domain of fractalkine and its interaction with an N-terminal fragment of CX3CR1.
Biochemistry, 38, 1999
1DOM
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SOLUTION STRUCTURE OF THE MONOCYTE CHEMOATTRACTANT PROTEIN-1 DIMER USING HETERONUCLEAR, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:MCP-1
Authors:Domaille, P.J., Handel, T.M.
Deposit date:1996-01-21
Release date:1996-10-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Heteronuclear (1H, 13C, 15N) NMR assignments and solution structure of the monocyte chemoattractant protein-1 (MCP-1) dimer.
Biochemistry, 35, 1996
1DON
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SOLUTION STRUCTURE OF THE MONOCYTE CHEMOATTRACTANT PROTEIN-1 DIMER USING HETERONUCLEAR, NMR, 20 STRUCTURES
Descriptor:MCP-1
Authors:Domaille, P.J., Handel, T.M.
Deposit date:1996-01-21
Release date:1996-10-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Heteronuclear (1H, 13C, 15N) NMR assignments and solution structure of the monocyte chemoattractant protein-1 (MCP-1) dimer.
Biochemistry, 35, 1996
1C3T
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ROTAMER STRAIN AS A DETERMINANT OF PROTEIN STRUCTURAL SPECIFICITY
Descriptor:PROTEIN (1D8 UBIQUITIN)
Authors:Lazar, G.A., Johnson, E.C., Desjarlais, J.R., Handel, T.M.
Deposit date:1999-07-28
Release date:1999-08-20
Last modified:2018-03-14
Method:SOLUTION NMR
Cite:Rotamer strain as a determinant of protein structural specificity.
Protein Sci., 8, 1999
1DOK
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MONOCYTE CHEMOATTRACTANT PROTEIN 1, P-FORM
Descriptor:MONOCYTE CHEMOATTRACTANT PROTEIN 1, SULFATE ION
Authors:Lubkowski, J., Bujacz, G., Boque, L., Wlodawer, A., Domaille, P.J., Handel, T.M.
Deposit date:1996-11-27
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions.
Nat.Struct.Biol., 4, 1997
1F2L
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CRYSTAL STRUCTURE OF CHEMOKINE DOMAIN OF FRACTALKINE
Descriptor:FRACTALKINE
Authors:Hoover, D.M., Mizoue, L.S., Handel, T.M., Lubkowski, J.
Deposit date:2000-05-26
Release date:2000-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of the chemokine domain of fractalkine shows a novel quaternary arrangement.
J.Biol.Chem., 275, 2000
1I1J
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STRUCTURE OF MELANOMA INHIBITORY ACTIVITY PROTEIN: A MEMBER OF A NEW FAMILY OF SECRETED PROTEINS
Descriptor:MELANOMA DERIVED GROWTH REGULATORY PROTEIN
Authors:Lougheed, J.C., Holton, J.M., Alber, T., Bazan, J.F., Handel, T.M.
Deposit date:2001-02-02
Release date:2001-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Structure of melanoma inhibitory activity protein, a member of a recently identified family of secreted proteins.
Proc.Natl.Acad.Sci.USA, 98, 2001
1K0X
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SOLUTION STRUCTURE OF MELANOMA INHIBITORY ACTIVITY PROTEIN
Descriptor:Melanoma Derived Growth Regulatory Protein
Authors:Lougheed, J.C., Domaille, P.J., Handel, T.M.
Deposit date:2001-09-21
Release date:2002-07-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and dynamics of melanoma inhibitory activity protein.
J.Biomol.NMR, 22, 2002
1UD7
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SOLUTION STRUCTURE OF THE DESIGNED HYDROPHOBIC CORE MUTANT OF UBIQUITIN, 1D7
Descriptor:PROTEIN (UBIQUITIN CORE MUTANT 1D7)
Authors:Johnson, E.C., Lazar, G.A., Desjarlais, J.R., Handel, T.M.
Deposit date:1999-04-07
Release date:1999-05-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and dynamics of a designed hydrophobic core variant of ubiquitin.
Structure Fold.Des., 7, 1999
2G2U
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CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) COMPLEX
Descriptor:Beta-lactamase SHV-1, Beta-lactamase inhibitory protein
Authors:Reynolds, K.A., Thomson, J.M., Corbett, K.D., Bethel, C.R., Berger, J.M., Kirsch, J.F., Bonomo, R.A., Handel, T.M.
Deposit date:2006-02-16
Release date:2006-07-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
2G2W
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CRYSTAL STRUCTURE OF THE SHV D104K BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) COMPLEX
Descriptor:Beta-lactamase SHV-1, Beta-lactamase inhibitory protein
Authors:Reynolds, K.A., Thomson, J.M., Corbett, K.D., Bethel, C.R., Berger, J.M., Kirsch, J.F., Bonomo, R.A., Handel, T.M.
Deposit date:2006-02-16
Release date:2006-07-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
2KUM
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SOLUTION STRUCTURE OF THE HUMAN CHEMOKINE CCL27
Descriptor:C-C motif chemokine 27
Authors:Kirkpatrick, J.P., Jansma, A., Hsu, A., Handel, T.M., Nietlispach, D.
Deposit date:2010-02-22
Release date:2010-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR analysis of the structure, dynamics, and unique oligomerization properties of the chemokine CCL27.
J.Biol.Chem., 285, 2010
2L9H
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OLIGOMERIC STRUCTURE OF THE CHEMOKINE CCL5/RANTES FROM NMR, MS, AND SAXS DATA
Descriptor:C-C motif chemokine 5
Authors:Wang, X., Watson, C.M., Sharp, J.S., Handel, T.M., Prestegard, J.H.
Deposit date:2011-02-09
Release date:2011-06-22
Last modified:2011-08-24
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Oligomeric Structure of the Chemokine CCL5/RANTES from NMR, MS, and SAXS Data.
Structure, 19, 2011
3C4O
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CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) E73M/S130K/S146M COMPLEX
Descriptor:Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION
Authors:Reynolds, K.A., Hanes, M.S., Thomson, J.M., Antczak, A.J., Berger, J.M., Bonomo, R.A., Kirsch, J.F., Handel, T.M.
Deposit date:2008-01-30
Release date:2008-05-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
3C4P
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CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) E73M COMPLEX
Descriptor:Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION
Authors:Reynolds, K.A., Hanes, M.S., Thomson, J.M., Antczak, A.J., Berger, J.M., Bonomo, R.A., Kirsch, J.F., Handel, T.M.
Deposit date:2008-01-30
Release date:2008-05-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
3E2K
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CRYSTAL STRUCTURE OF THE KPC-2 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP)
Descriptor:Carbapenemase, Beta-lactamase inhibitory protein
Authors:Hanes, M.S., Jude, K.M., Berger, J.M., Bonomo, R.A., Handel, T.M.
Deposit date:2008-08-05
Release date:2009-08-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein
Biochemistry, 48, 2009
3E2L
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CRYSTAL STRUCTURE OF THE KPC-2 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP)
Descriptor:Carbapenemase, Beta-lactamase inhibitory protein
Authors:Hanes, M.S., Jude, K.M., Berger, J.M., Kirsch, J.F., Bonomo, R.A., Handel, T.M.
Deposit date:2008-08-05
Release date:2009-08-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein
Biochemistry, 48, 2009
3N4I
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CRYSTAL STRUCTURE OF THE SHV-1 D104E BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) COMPLEX
Descriptor:Beta-lactamase SHV-1, Beta-lactamase inhibitory protein
Authors:Hanes, M.S., Reynolds, K.A., McNamara, C., Ghosh, P., Bonomo, R.A., Kirsch, J.F., Handel, T.M.
Deposit date:2010-05-21
Release date:2011-03-09
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Specificity and Cooperativity at beta-lactamase Position 104 in TEM-1/BLIP and SHV-1/BLIP interactions
Proteins, 79, 2011
4RWS
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CRYSTAL STRUCTURE OF CXCR4 AND VIRAL CHEMOKINE ANTAGONIST VMIP-II COMPLEX (PSI COMMUNITY TARGET)
Descriptor:C-X-C chemokine receptor type 4/Endolysin chimeric protein, Viral macrophage inflammatory protein 2
Authors:Qin, L., Kufareva, I., Holden, L., Wang, C., Zheng, Y., Wu, H., Fenalti, G., Han, G.W., Cherezov, V., Abagyan, R., Stevens, R.C., Handel, T.M., GPCR Network (GPCR)
Deposit date:2014-12-05
Release date:2015-02-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine.
Science, 347, 2015
5T1A
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STRUCTURE OF CC CHEMOKINE RECEPTOR 2 WITH ORTHOSTERIC AND ALLOSTERIC ANTAGONISTS
Descriptor:Chimera protein of CC chemokine receptor type 2 isoform B and T4-lysozyme,Lysozyme, (3S)-1-{(1S,2R,4R)-4-[methyl(propan-2-yl)amino]-2-propylcyclohexyl}-3-{[6-(trifluoromethyl)quinazolin-4-yl]amino}pyrrolidin-2-one, (2~{R})-1-(4-chloranyl-2-fluoranyl-phenyl)-2-cyclohexyl-3-ethanoyl-4-oxidanyl-2~{H}-pyrrol-5-one, ...
Authors:Zheng, Y., Qin, L., Ortiz Zacarias, N.V., de Vries, H., Han, G.W., Gustavsson, M., Dabros, M., Zhao, C., Cherney, R.J., Carter, P., Stamos, D., Abagyan, R., Cherezov, V., Stevens, R.C., IJzerman, A.P., Heitman, L.H., Tebben, A., Kufareva, I., Handel, T.M.
Deposit date:2016-08-18
Release date:2016-12-14
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists.
Nature, 540, 2016
5UIW
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CRYSTAL STRUCTURE OF CC CHEMOKINE RECEPTOR 5 (CCR5) IN COMPLEX WITH HIGH POTENCY HIV ENTRY INHIBITOR 5P7-CCL5
Descriptor:C-C chemokine receptor type 5,Rubredoxin chimera, C-C motif chemokine 5, ZINC ION, ...
Authors:Zheng, Y., Qin, L., Han, G.W., Gustavsson, M., Kawamura, T., Stevens, R.C., Cherezov, V., Kufareva, I., Handel, T.M.
Deposit date:2017-01-15
Release date:2017-06-28
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV.
Immunity, 46, 2017
1DOL
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MONOCYTE CHEMOATTRACTANT PROTEIN 1, I-FORM
Descriptor:MONOCYTE CHEMOATTRACTANT PROTEIN 1
Authors:Lubkowski, J., Bujacz, G., Boque, L., Wlodawer, A.
Deposit date:1996-11-22
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions.
Nat.Struct.Biol., 4, 1997
1MKF
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VIRAL CHEMOKINE BINDING PROTEIN M3 FROM MURINE GAMMAHERPESVIRUS 68
Descriptor:M3
Authors:Alexander, J.M., Fremont, D.H., Midwest Center for Structural Genomics (MCSG)
Deposit date:2002-08-29
Release date:2002-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of Chemokine Sequestration by a Herpesvirus Decoy Receptor
Cell(Cambridge,Mass.), 111, 2002
1ML0
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VIRAL CHEMOKINE BINDING PROTEIN M3 FROM MURINE GAMMAHERPESVIRUS68 IN COMPLEX WITH THE P8A VARIANT OF CC-CHEMOKINE MCP-1
Descriptor:M3 Protein, Small Inducible Cytokine
Authors:Alexander, J.M., Fremont, D.H.
Deposit date:2002-08-29
Release date:2002-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Chemokine Sequestration by a Herpesvirus Decoy Receptor
Cell(Cambridge,Mass.), 111, 2002
2KNX
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SOLUTION STRUCTURE OF COMPLEMENT REPEAT CR17 FROM LRP-1
Descriptor:Prolow-density lipoprotein receptor-related protein 1, CALCIUM ION
Authors:Guttman, M., Komives, E.
Deposit date:2009-09-07
Release date:2010-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the minimal interface between ApoE and LRP.
J.Mol.Biol., 398, 2010
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