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5EJO
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CRYSTAL STRUCTURE OF THE WINGED HELIX DOMAIN IN CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT P90
分子名称:Chromatin assembly factor 1 subunit p90
著者Zhang, K., Gao, Y., Li, J., Burgess, R., Han, J., Liang, H., Zhang, Z., Liu, Y.
登録日2015-11-02
公開日2016-03-16
最終更新日2016-07-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks
Nucleic Acids Res., 44, 2016
1LJT
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CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COMPLEXED WITH (S,R)-3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER (ISO-1)
分子名称:Macrophage migration inhibitory factor, 3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER
著者Lubetsky, J.B., Dios, A., Han, J., Aljabari, B., Ruzsicska, B., Mitchell, R., Lolis, E., Al-Abed, Y.
登録日2002-04-22
公開日2002-11-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Tautomerase Active Site of Macrophage Migration Inhibitory factor is a Potential Target for Discovery of Novel Anti-inflammatory Agents
J.Biol.Chem., 277, 2002
3UL7
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CRYSTAL STRUCTURE OF THE TV3 MUTANT F63W
分子名称:Toll-like receptor 4, Variable lymphocyte receptor B, N-ACETYL-D-GLUCOSAMINE, ...
著者Kim, H.J., Cheong, H.K., Jeon, Y.H.
登録日2011-11-10
公開日2012-04-04
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
3UL8
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CRYSTAL STRUCTURE OF THE TV3 MUTANT V134L
分子名称:Toll-like receptor 4, Variable lymphocyte receptor B, N-ACETYL-D-GLUCOSAMINE, ...
著者Kim, H.J., Cheong, H.K., Jeon, Y.H.
登録日2011-11-10
公開日2012-04-04
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
3UL9
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STRUCTURE OF THE TV3 MUTANT M41E
分子名称:Toll-like receptor 4, Variable lymphocyte receptor B, N-ACETYL-D-GLUCOSAMINE, ...
著者Kim, H.J., Cheong, H.K., Jeon, Y.H.
登録日2011-11-10
公開日2012-05-23
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
3ULA
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CRYSTAL STRUCTURE OF THE TV3 MUTANT F63W-MD-2-ERITORAN COMPLEX
分子名称:Toll-like receptor 4, Variable lymphocyte receptor B, Lymphocyte antigen 96, ...
著者Kim, H.J., Cheong, H.K., Jeon, Y.H.
登録日2011-11-10
公開日2012-04-04
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
4NSQ
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CRYSTAL STRUCTURE OF PCAF
分子名称:Histone acetyltransferase KAT2B, COENZYME A
著者Lin, J.Y., Cai, Y.F.
登録日2013-11-28
公開日2014-03-05
実験手法X-RAY DIFFRACTION (2.3108 Å)
主引用文献Dimeric structure of p300/CBP associated factor.
Bmc Struct.Biol., 14, 2014
5BXJ
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COMPLEX OF THE FK1 DOMAIN MUTANT A19T OF FKBP51 WITH 4-NITROPHENOL
分子名称:Peptidyl-prolyl cis-trans isomerase FKBP5, P-NITROPHENOL
著者Wu, D., Tao, X., Chen, Z., Han, J., Jia, W., Li, X., Wang, Z., He, Y.X.
登録日2015-06-09
公開日2016-05-25
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells
J. Hazard. Mater., 307, 2016
5XS3
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CRYSTAL STRUCTURE OF HLA CLASS I ANTIGEN
分子名称:Heavy Chain, Light Chain, P
著者Wei, P.C., Yang, Y., Liu, Z.X., Luo, Z.Q., Tu, W.Y., Han, J.Y., Deng, Y.H., Yin, L.
登録日2017-06-12
公開日2017-09-13
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Characterization of Autoantigen Presentation by HLA-C*06:02 in Psoriasis
J. Invest. Dermatol., 137, 2017
2MSY
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SOLUTION STRUCTURE OF HOX HOMEODOMAIN
分子名称:Homeobox protein Hox-C9
著者Kim, H., Park, S., Han, J., Lee, B.
登録日2014-08-11
公開日2015-09-16
最終更新日2015-10-07
実験手法SOLUTION NMR
主引用文献Structural insight into the interaction between the Hox and HMGB1 and understanding of the HMGB1-enhancing effect of Hox-DNA binding.
Biochim.Biophys.Acta, 1854, 2015
5F59
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THE CRYSTAL STRUCTURE OF MLL3 SET DOMAIN
分子名称:Histone-lysine N-methyltransferase 2C, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE
著者Li, Y., Lei, M., Chen, Y.
登録日2015-12-04
公開日2016-02-24
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F5E
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THE CRYSTAL STRUCTURE OF MLL1 SET DOMAIN WITH N3816I/Q3867L MUTATION
分子名称:Histone-lysine N-methyltransferase 2A, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE
著者Li, Y., Lei, M., Chen, Y.
登録日2015-12-04
公開日2016-02-24
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6K
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CRYSTAL STRUCTURE OF THE MLL3-ASH2L-RBBP5 COMPLEX
分子名称:Set1/Ash2 histone methyltransferase complex subunit ASH2,Set1/Ash2 histone methyltransferase complex subunit ASH2, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ...
著者Li, Y., Lei, M., Chen, Y.
登録日2015-12-06
公開日2016-02-24
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (2.411 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6L
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THE CRYSTAL STRUCTURE OF MLL1 (N3861I/Q3867L) IN COMPLEX WITH RBBP5 AND ASH2L
分子名称:Retinoblastoma-binding protein 5, Set1/Ash2 histone methyltransferase complex subunit ASH2, Histone-lysine N-methyltransferase 2A, ...
著者Li, Y., Lei, M., Chen, Y.
登録日2015-12-06
公開日2016-02-24
最終更新日2016-04-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
3OUL
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CRYSTAL STRUCTURE OF TOXOFLAVIN-DEGRADING ENZYME IN A SUBSTRATE-FREE FORM
分子名称:Toxoflavin-degrading enzyme, MANGANESE (II) ION
著者Kim, M.I., Rhee, S.
登録日2010-09-15
公開日2011-08-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and functional analysis of phytotoxin toxoflavin-degrading enzyme
Plos One, 6, 2011
3OUM
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CRYSTAL STRUCTURE OF TOXOFLAVIN-DEGRADING ENZYME IN COMPLEX WITH TOXOFLAVIN
分子名称:toxoflavin-degrading enzyme, MANGANESE (II) ION, 1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
著者Kim, M.I., Rhee, S.
登録日2010-09-15
公開日2011-08-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and functional analysis of phytotoxin toxoflavin-degrading enzyme
Plos One, 6, 2011
3W2D
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL EENTEROTOXIN B IN COMPLEX WITH A NOVEL NEUTRALIZATION MONOCLONAL ANTIBODY FAB FRAGMENT
分子名称:Enterotoxin type B, Monoclonal Antibody 3E2 Fab figment light chain, Monoclonal Antibody 3E2 Fab figment heavy chain, ...
著者Liang, S.Y., Hu, S., Dai, J.X., Guo, Y.J., Lou, Z.Y.
登録日2012-11-28
公開日2013-12-25
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for the neutralization and specificity of Staphylococcal enterotoxin B against its MHC Class II binding site.
MAbs, 6, 2014
4OWI
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PEPTIDE STRUCTURE
分子名称:p53LZ2
著者Lee, J.-H.
登録日2014-02-02
公開日2014-05-21
最終更新日2015-01-14
実験手法X-RAY DIFFRACTION (1.202 Å)
主引用文献Protein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitor.
Nat Commun, 5, 2014
1A9U
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB203580
分子名称:MAP KINASE P38, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE
著者Wang, Z., Canagarajah, B., Boehm, J.C., Kassis, S., Cobb, M.H., Young, P.R., Abdel-Meguid, S., Adams, J.L., Goldsmith, E.J.
登録日1998-04-10
公開日1999-04-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BL6
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB216995
分子名称:PROTEIN (MAP KINASE P38), 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE
著者Wang, Z., Canagarajah, B.J., Boehm, J.C., Kassis, S., Cobb, M.H., Young, P.R., Abdel-Meguid, S., Adams, J.L., Goldsmith, E.J.
登録日1998-07-11
公開日1999-07-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BL7
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB220025
分子名称:PROTEIN (MAP KINASE P38), 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE
著者Wang, Z., Canagarajah, B.J., Boehm, J.C., Kassis, S., Cobb, M.H., Young, P.R., Abdel-Meguid, S., Adams, J.L., Goldsmith, E.J.
登録日1998-07-23
公開日1999-07-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BMK
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB218655
分子名称:PROTEIN (MAP KINASE P38), 4-(FLUOROPHENYL)-1-CYCLOPROPYLMETHYL-5-(2-AMINO-4-PYRIMIDINYL)IMIDAZOLE
著者Wang, Z., Canagarajah, B., Boehm, J.C., Kassis, S., Cobb, M.H., Young, P.R., Abdel-Meguid, S., Adams, J.L., Goldsmith, E.J.
登録日1998-07-23
公開日1999-07-23
最終更新日2017-02-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
4JGV
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CRYSTAL STRUCTURE OF HUMAN NUR77 LIGAND-BINDING DOMAIN IN COMPLEX WITH THPN
分子名称:Nuclear receptor subfamily 4 group A member 1, 1-(3,4,5-trihydroxyphenyl)nonan-1-one, GLYCEROL
著者Zhang, Q., Li, F., Li, A., Tian, X., Wan, W., Wan, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
登録日2013-03-04
公開日2013-12-18
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway.
Nat.Chem.Biol., 10, 2014
4KZI
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CRYSTAL STRUCTURE OF TR3 LBD IN COMPLEX WITH DPDO
分子名称:Nuclear receptor subfamily 4 group A member 1, GLYCEROL, 1-(3,5-dimethoxyphenyl)decan-1-one
著者Li, F., Zhang, Q., Li, A., Tian, X., Cai, Q., Wang, W., Wang, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
登録日2013-05-30
公開日2013-12-18
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling
Nat.Struct.Mol.Biol., 2013
4KZJ
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CRYSTAL STRUCTURE OF TR3 LBD L449W MUTANT
分子名称:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
著者Li, F., Zhang, Q., Li, A., Tian, X., Cai, Q., Wang, W., Wang, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
登録日2013-05-30
公開日2013-12-18
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling
Nat.Struct.Mol.Biol., 2013
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