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5ZB5
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THE STRUCTURAL BASIS OF HISTONE CHAPERONEVPS75
Descriptor:NAP family histone chaperone vps75, DI(HYDROXYETHYL)ETHER, GLYCEROL
Authors:Chen, Y., Yang, Z., Dou, Y., Deren, L., Meilin, W., Sidan, X., Hua, J., Huiyan, L.
Deposit date:2018-02-09
Release date:2019-02-13
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Structural basis for the acetylation of histone H3K9 and H3K27 mediated by the histone chaperone Vps75 inPneumocystis carinii.
Signal Transduct Target Ther, 4, 2019
5YPS
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THE STRUCTURAL BASIS OF HISTONE CHAPERONEVPS75
Descriptor:Vacuolar protein sorting-associated protein 75, CALCIUM ION, PENTAETHYLENE GLYCOL, ...
Authors:Chen, Y., Zhang, Y., Dou, Y., Lu, D., Meilin, W., Sidan, X., Hua, J., Limper, A.H.
Deposit date:2017-11-03
Release date:2018-11-07
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Structural basis for the acetylation of histone H3K9 and H3K27 mediated by the histone chaperone Vps75 inPneumocystis carinii.
Signal Transduct Target Ther, 4, 2019
5XS3
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CRYSTAL STRUCTURE OF HLA CLASS I ANTIGEN
Descriptor:Heavy Chain, Light Chain, P
Authors:Wei, P.C., Yang, Y., Liu, Z.X., Luo, Z.Q., Tu, W.Y., Han, J.Y., Deng, Y.H., Yin, L.
Deposit date:2017-06-12
Release date:2017-09-13
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Characterization of Autoantigen Presentation by HLA-C*06:02 in Psoriasis
J. Invest. Dermatol., 137, 2017
5UQ9
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CRYSTAL STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE WITH ((4R,5R)-5-(HYDROXYCARBAMOYL)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YL)METHYL DIHYDROGEN PHOSPHATE
Descriptor:6-phosphogluconate dehydrogenase, decarboxylating, [(4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl dihydrogen phosphate
Authors:Leonard, P.G.
Deposit date:2017-02-07
Release date:2018-08-22
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation.
Cell Rep, 26, 2019
5UOJ
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THE STRUCTURE OF THE MAP KINASE P38 AT 2.1 ANGSTROMS RESOLUTION
Descriptor:Mitogen-activated protein kinase 14
Authors:CHLEBOWICZ, J., WANG, Z., GOLDSMITH, E.J.
Deposit date:2017-01-31
Release date:2017-02-22
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of mitogen-activated protein kinase p38 at 2.1-A resolution.
Proc. Natl. Acad. Sci. U.S.A., 94, 1997
5F6L
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THE CRYSTAL STRUCTURE OF MLL1 (N3861I/Q3867L) IN COMPLEX WITH RBBP5 AND ASH2L
Descriptor:Retinoblastoma-binding protein 5, Set1/Ash2 histone methyltransferase complex subunit ASH2, Histone-lysine N-methyltransferase 2A, ...
Authors:Li, Y., Lei, M., Chen, Y.
Deposit date:2015-12-06
Release date:2016-02-24
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6K
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CRYSTAL STRUCTURE OF THE MLL3-ASH2L-RBBP5 COMPLEX
Descriptor:Set1/Ash2 histone methyltransferase complex subunit ASH2,Set1/Ash2 histone methyltransferase complex subunit ASH2, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ...
Authors:Li, Y., Lei, M., Chen, Y.
Deposit date:2015-12-06
Release date:2016-02-24
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (2.411 Å)
Cite:Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F5E
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THE CRYSTAL STRUCTURE OF MLL1 SET DOMAIN WITH N3816I/Q3867L MUTATION
Descriptor:Histone-lysine N-methyltransferase 2A, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Li, Y., Lei, M., Chen, Y.
Deposit date:2015-12-04
Release date:2016-02-24
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F59
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THE CRYSTAL STRUCTURE OF MLL3 SET DOMAIN
Descriptor:Histone-lysine N-methyltransferase 2C, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Li, Y., Lei, M., Chen, Y.
Deposit date:2015-12-04
Release date:2016-02-24
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5EJO
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CRYSTAL STRUCTURE OF THE WINGED HELIX DOMAIN IN CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT P90
Descriptor:Chromatin assembly factor 1 subunit p90
Authors:Zhang, K., Gao, Y., Li, J., Burgess, R., Han, J., Liang, H., Zhang, Z., Liu, Y.
Deposit date:2015-11-02
Release date:2016-03-16
Last modified:2016-07-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks
Nucleic Acids Res., 44, 2016
5BXJ
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COMPLEX OF THE FK1 DOMAIN MUTANT A19T OF FKBP51 WITH 4-NITROPHENOL
Descriptor:Peptidyl-prolyl cis-trans isomerase FKBP5, P-NITROPHENOL
Authors:Wu, D., Tao, X., Chen, Z., Han, J., Jia, W., Li, X., Wang, Z., He, Y.X.
Deposit date:2015-06-09
Release date:2016-05-25
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells
J. Hazard. Mater., 307, 2016
4RZG
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CRYSTAL STRUCTURE ANALYSIS OF THE DNPA-BOUNDED NUR77 LIGAND BINDING DOMAIN
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL, pentyl (3,5-dihydroxy-2-nonanoylphenyl)acetate
Authors:Li, F., Tian, X., Li, A., Li, L., Liu, Y., Chen, H., Wu, Q., Lin, T.
Deposit date:2014-12-21
Release date:2015-03-18
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
4RZF
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CRYSTAL STRUCTURE ANALYSIS OF THE NUR77 LIGAND BINDING DOMAIN, S441W MUTANT
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Li, F., Tian, X., Li, A., Li, L., Liu, Y., Chen, H., Wu, Q., Lin, T.
Deposit date:2014-12-21
Release date:2015-03-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
4RZE
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CRYSTAL STRUCTURE ANALYSIS OF THE NUR77 LIGAND BINDING DOMAIN, L437W,D594E MUTANT
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Fengwei, L., Xuyang, T., Anzhong, L., Li, L., Yuan, L., Hangzi, C., Qiao, W., Tianwei, L.
Deposit date:2014-12-21
Release date:2015-03-18
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
4OWI
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PEPTIDE STRUCTURE
Descriptor:p53LZ2
Authors:Lee, J.-H.
Deposit date:2014-02-02
Release date:2014-05-21
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (1.202 Å)
Cite:Protein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitor.
Nat Commun, 5, 2014
4NSQ
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CRYSTAL STRUCTURE OF PCAF
Descriptor:Histone acetyltransferase KAT2B, COENZYME A
Authors:Lin, J.Y., Cai, Y.F.
Deposit date:2013-11-28
Release date:2014-03-05
Method:X-RAY DIFFRACTION (2.3108 Å)
Cite:Dimeric structure of p300/CBP associated factor.
Bmc Struct.Biol., 14, 2014
4KZM
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CRYSTAL STRUCTURE OF TR3 LBD S553A MUTANT
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Li, F., Zhang, Q., Li, A., Tian, X., Cai, Q., Wang, W., Wang, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-05-30
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling
Nat.Struct.Mol.Biol., 2013
4KZJ
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CRYSTAL STRUCTURE OF TR3 LBD L449W MUTANT
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
Authors:Li, F., Zhang, Q., Li, A., Tian, X., Cai, Q., Wang, W., Wang, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-05-30
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling
Nat.Struct.Mol.Biol., 2013
4KZI
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CRYSTAL STRUCTURE OF TR3 LBD IN COMPLEX WITH DPDO
Descriptor:Nuclear receptor subfamily 4 group A member 1, GLYCEROL, 1-(3,5-dimethoxyphenyl)decan-1-one
Authors:Li, F., Zhang, Q., Li, A., Tian, X., Cai, Q., Wang, W., Wang, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-05-30
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling
Nat.Struct.Mol.Biol., 2013
4JGV
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CRYSTAL STRUCTURE OF HUMAN NUR77 LIGAND-BINDING DOMAIN IN COMPLEX WITH THPN
Descriptor:Nuclear receptor subfamily 4 group A member 1, 1-(3,4,5-trihydroxyphenyl)nonan-1-one, GLYCEROL
Authors:Zhang, Q., Li, F., Li, A., Tian, X., Wan, W., Wan, Y., Chen, H., Xing, Y., Wu, Q., Lin, T.
Deposit date:2013-03-04
Release date:2013-12-18
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway.
Nat.Chem.Biol., 10, 2014
3W2D
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL EENTEROTOXIN B IN COMPLEX WITH A NOVEL NEUTRALIZATION MONOCLONAL ANTIBODY FAB FRAGMENT
Descriptor:Enterotoxin type B, Monoclonal Antibody 3E2 Fab figment light chain, Monoclonal Antibody 3E2 Fab figment heavy chain, ...
Authors:Liang, S.Y., Hu, S., Dai, J.X., Guo, Y.J., Lou, Z.Y.
Deposit date:2012-11-28
Release date:2013-12-25
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the neutralization and specificity of Staphylococcal enterotoxin B against its MHC Class II binding site.
MAbs, 6, 2014
3ULA
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CRYSTAL STRUCTURE OF THE TV3 MUTANT F63W-MD-2-ERITORAN COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B, Lymphocyte antigen 96, ...
Authors:Kim, H.J., Cheong, H.K., Jeon, Y.H.
Deposit date:2011-11-10
Release date:2012-04-04
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
3UL9
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STRUCTURE OF THE TV3 MUTANT M41E
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kim, H.J., Cheong, H.K., Jeon, Y.H.
Deposit date:2011-11-10
Release date:2012-05-23
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
3UL8
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CRYSTAL STRUCTURE OF THE TV3 MUTANT V134L
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kim, H.J., Cheong, H.K., Jeon, Y.H.
Deposit date:2011-11-10
Release date:2012-04-04
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
3UL7
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CRYSTAL STRUCTURE OF THE TV3 MUTANT F63W
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kim, H.J., Cheong, H.K., Jeon, Y.H.
Deposit date:2011-11-10
Release date:2012-04-04
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
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