Author results

1N6J
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STRUCTURAL BASIS OF SEQUENCE-SPECIFIC RECRUITMENT OF HISTONE DEACETYLASES BY MYOCYTE ENHANCER FACTOR-2
Descriptor:5'-D(*AP*GP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*CP*T)-3', Myocyte-specific enhancer factor 2B, ...
Authors:Han, A., Pan, F., Stroud, J.C., Youn, H.D., Liu, J.O., Chen, L.
Deposit date:2002-11-11
Release date:2003-11-11
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2
Nature, 422, 2003
1TQE
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MECHANISM OF RECRUITMENT OF CLASS II HISTONE DEACETYLASES BY MYOCYTE ENHANCER FACTOR-2
Descriptor:MEF2 binding site of nur77 promoter, Myocyte-specific enhancer factor 2B, Histone deacetylase 9
Authors:Chen, L., Han, A., He, J., Wu, Y., Liu, J.O.
Deposit date:2004-06-17
Release date:2004-12-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism of Recruitment of Class II Histone Deacetylases by Myocyte Enhancer Factor-2.
J.Mol.Biol., 345, 2005
1LTU
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CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM, APO (NO IRON BOUND) STRUCTURE
Descriptor:PHENYLALANINE-4-HYDROXYLASE
Authors:Erlandsen, H., Kim, J.Y., Patch, M.G., Han, A., Volner, A., Abu-Omar, M.M., Stevens, R.C.
Deposit date:2002-05-20
Release date:2002-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1LTV
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CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE WITH BOUND OXIDIZED FE(III)
Descriptor:PHENYLALANINE-4-HYDROXYLASE, FE (III) ION
Authors:Erlandsen, H., Kim, J.Y., Patch, M.G., Han, A., Volner, A., Abu-Omar, M.M., Stevens, R.C.
Deposit date:2002-05-20
Release date:2002-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1LTZ
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CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE HAS BOUND IRON (III) AND OXIDIZED COFACTOR 7,8-DIHYDROBIOPTERIN
Descriptor:PHENYLALANINE-4-HYDROXYLASE, FE (III) ION, CHLORIDE ION, ...
Authors:Erlandsen, H., Kim, J.Y., Patch, M.G., Han, A., Volner, A., Abu-Omar, M.M., Stevens, R.C.
Deposit date:2002-05-21
Release date:2002-07-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1R4K
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SOLUTION STRUCTURE OF THE DROSOPHILA ARGONAUTE 1 PAZ DOMAIN
Descriptor:Argonaute 1
Authors:Yan, K.S., Yan, S., Farooq, A., Han, A., Zeng, L., Zhou, M.-M.
Deposit date:2003-10-07
Release date:2003-12-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and conserved RNA binding of the PAZ domain
Nature, 426, 2003
2AS5
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STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT AND FOXP2 BOUND SPECIFICALLY TO DNA.
Descriptor:5'-D(TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*GP*)-3', 5'-D(AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*TP*)-3', Nuclear factor of activated T-cells, ...
Authors:Wu, Y., Stroud, J.C., Borde, M., Bates, D.L., Guo, L., Han, A., Rao, A., Chen, L.
Deposit date:2005-08-22
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT.
Cell(Cambridge,Mass.), 126, 2006
3GUT
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CRYSTAL STRUCTURE OF A HIGHER-ORDER COMPLEX OF P50:RELA BOUND TO THE HIV-1 LTR
Descriptor:Transcription factor p65, Nuclear factor NF-kappa-B p105 subunit, HIV-LTR Core Forward Strand, ...
Authors:Stroud, J.C., Oltman, A.J., Han, A., Bates, D.L., Chen, L.
Deposit date:2009-03-30
Release date:2009-09-08
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Structural basis of HIV-1 activation by NF-kappaB--a higher-order complex of p50:RelA bound to the HIV-1 LTR.
J.Mol.Biol., 393, 2009
2A07
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CRYSTAL STRUCTURE OF FOXP2 BOUND SPECIFICALLY TO DNA.
Descriptor:5'-D(*AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*T)-3', 5'-D(*TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*G)-3', Forkhead box protein P2, ...
Authors:Stroud, J.C., Wu, Y., Bates, D.L., Han, A., Nowick, K., Paabo, S., Tong, H., Chen, L.
Deposit date:2005-06-16
Release date:2006-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Forkhead Domain of FOXP2 Bound to DNA.
Structure, 14, 2006
2H8N
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STRUCTURE OF A GLUTAMINE-RICH DOMAIN FROM HISTONE DEACETYLASE 4
Descriptor:Histone deacetylase 4
Authors:Guo, L., Han, A., Bates, D.L., Chen, L.
Deposit date:2006-06-07
Release date:2007-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2O94
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THE 97H/F MUTANT STRUCTURE OF A GLUTAMINE-RICH DOMAIN FROM HISTONE DEACETYLASE 4
Descriptor:Histone deacetylase 4
Authors:Guo, L., Han, A., Bates, D.L., Chen, L.
Deposit date:2006-12-13
Release date:2007-02-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3KOV
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STRUCTURE OF MEF2A BOUND TO DNA REVEALS A COMPLETELY FOLDED MADS-BOX/MEF2 DOMAIN THAT RECOGNIZES DNA AND RECRUITS TRANSCRIPTION CO-FACTORS
Descriptor:Myocyte-specific enhancer factor 2A, DNA (5'-D(*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*T)-3')
Authors:Wu, Y., Dey, R., Han, A., Jayathilaka, N., Philips, M., Ye, J., Chen, L.
Deposit date:2009-11-14
Release date:2010-02-16
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the MADS-box/MEF2 Domain of MEF2A Bound to DNA and Its Implication for Myocardin Recruitment.
J.Mol.Biol., 397, 2010
3MU6
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INHIBITING THE BINDING OF CLASS IIA HISTONE DEACETYLASES TO MYOCYTE ENHANCER FACTOR-2 BY SMALL MOLECULES
Descriptor:Myocyte-specific enhancer factor 2A, DNA (5'-D(*AP*AP*AP*GP*CP*TP*AP*TP*TP*AP*TP*TP*AP*GP*CP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*GP*CP*TP*AP*AP*TP*AP*AP*TP*AP*GP*CP*TP*T)-3'), ...
Authors:Jayathilaka, N., Han, A., Gaffney, K., Dey, R., He, J., Ye, J., Gao, T., Petasis, N.A., Chen, L.
Deposit date:2010-05-01
Release date:2011-11-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.434 Å)
Cite:Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2.
Nucleic Acids Res., 40, 2012
5DN8
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1.76 ANGSTROM CRYSTAL STRUCTURE OF GTP-BINDING PROTEIN DER FROM COXIELLA BURNETII IN COMPLEX WITH GDP.
Descriptor:GTPase Der, GUANOSINE-5'-DIPHOSPHATE
Authors:Minasov, G., Shuvalova, L., Han, A., Kim, H.-Y., Grimshaw, S., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2015-09-09
Release date:2015-10-14
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:1.76 Angstrom Crystal Structure of GTP-binding Protein Der from Coxiella burnetii in Complex with GDP.
To Be Published
5K04
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THE NATB ACETYLTRANSFERASE COMPLEX BOUND TO COA AND MES
Descriptor:Uncharacterized protein, N-terminal acetyltransferase B complex subunit NAT3, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Hong, H., Cai, Y., Zhang, S., Han, A.
Deposit date:2016-05-17
Release date:2017-04-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Basis of Substrate Specific Acetylation by N-Terminal Acetyltransferase NatB
Structure, 25, 2017
5K18
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THE NATB ACETYLTRANSFERASE COMPLEX BOUND TO BISUBSTRATE INHIBITOR
Descriptor:Uncharacterized protein, N-terminal acetyltransferase B complex subunit NAT3, Bisubstrate inhibitor, ...
Authors:Hong, H., Cai, Y., Zhang, S., Han, A.
Deposit date:2016-05-17
Release date:2017-04-19
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Molecular Basis of Substrate Specific Acetylation by N-Terminal Acetyltransferase NatB
Structure, 25, 2017
5EY0
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CRYSTAL STRUCTURE OF CODY FROM STAPHYLOCOCCUS AUREUS WITH GTP AND ILE
Descriptor:GTP-sensing transcriptional pleiotropic repressor CodY, ISOLEUCINE, GUANOSINE-5'-TRIPHOSPHATE
Authors:Han, A., Hwang, K.Y.
Deposit date:2015-11-24
Release date:2016-09-14
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
Nucleic Acids Res., 44, 2016
5EY1
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CRYSTAL STRUCTURE OF CODY FROM STAPHYLOCOCCUS AUREUS WITH GTP AND ILE
Descriptor:GTP-sensing transcriptional pleiotropic repressor CodY, ISOLEUCINE, GUANOSINE-5'-TRIPHOSPHATE
Authors:Han, A., Hwang, K.Y.
Deposit date:2015-11-24
Release date:2016-09-14
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
Nucleic Acids Res., 44, 2016
5EY2
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CRYSTAL STRUCTURE OF CODY FROM BACILLUS CEREUS
Descriptor:GTP-sensing transcriptional pleiotropic repressor CodY
Authors:Han, A., Lee, W.C., Son, J., Kim, S.H., Hwang, K.Y.
Deposit date:2015-11-24
Release date:2016-09-14
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
Nucleic Acids Res., 44, 2016
5FA9
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BIFUNCTIONAL METHIONINE SULFOXIDE REDUCTASE AB (MSRAB) FROM TREPONEMA DENTICOLA
Descriptor:Peptide methionine sulfoxide reductase MsrA, (4S,5S)-1,2-DITHIANE-4,5-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE
Authors:Han, A., Son, J., Kim, H.-Y., Hwang, K.Y.
Deposit date:2015-12-11
Release date:2016-09-14
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Essential Role of the Linker Region in the Higher Catalytic Efficiency of a Bifunctional MsrA-MsrB Fusion Protein
Biochemistry, 55, 2016
4NSQ
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CRYSTAL STRUCTURE OF PCAF
Descriptor:Histone acetyltransferase KAT2B, COENZYME A
Authors:Lin, J.Y., Cai, Y.F.
Deposit date:2013-11-28
Release date:2014-03-05
Method:X-RAY DIFFRACTION (2.3108 Å)
Cite:Dimeric structure of p300/CBP associated factor.
Bmc Struct.Biol., 14, 2014
6CFD
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ADEP4 BOUND TO E. FAECIUM CLPP
Descriptor:ATP-dependent Clp protease proteolytic subunit, (4S)-2-METHYL-2,4-PENTANEDIOL, N-[(6aS,12S,15aS,17R,21R,23aS)-17,21-dimethyl-6,11,15,20,23-pentaoxooctadecahydro-2H,6H,11H,15H-pyrido[2,1-i]dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13]oxatetraazacyclohexadecin-12-yl]-3,5-difluoro-Nalpha-[(2E)-hept-2-enoyl]-L-phenylalaninamide
Authors:Lee, R.E., Griffith, E.C.
Deposit date:2018-02-14
Release date:2018-05-16
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:In VivoandIn VitroEffects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci.
Antimicrob. Agents Chemother., 62, 2018
4U7N
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INACTIVE STRUCTURE OF HISTIDINE KINASE
Descriptor:Histidine protein kinase sensor protein
Authors:Cai, Y., Hu, X., Sang, J.
Deposit date:2014-07-31
Release date:2015-09-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Conformational dynamics of the essential sensor histidine kinase WalK.
Acta Crystallogr D Struct Biol, 73, 2017
4U7O
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ACTIVE HISTIDINE KINASE BOUND WITH ATP
Descriptor:Histidine protein kinase sensor protein, AMP PHOSPHORAMIDATE
Authors:Cai, Y., Hu, X., Sang, J.
Deposit date:2014-07-31
Release date:2015-09-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.395 Å)
Cite:Conformational dynamics of the essential sensor histidine kinase WalK.
Acta Crystallogr D Struct Biol, 73, 2017
4ZKI
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THE CRYSTAL STRUCTURE OF HISTIDINE KINASE YYCG WITH ADP
Descriptor:Histidine kinase, ADENOSINE-5'-DIPHOSPHATE
Authors:Cai, Y.
Deposit date:2015-04-30
Release date:2016-05-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.401 Å)
Cite:Conformational dynamics of the essential sensor histidine kinase WalK
Acta Crystallogr D Struct Biol, 73, 2017
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