Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7NM5
DownloadVisualize
BU of 7nm5 by Molmil
Solution structure of MLKL executioner domain in complex with a fragment
Descriptor: 2-[(~{S})-methoxy-(4-phenylphenyl)methyl]-3~{H}-benzimidazole-5-carboxylic acid, Mixed lineage kinase domain-like protein
Authors:Ruebbelke, M, Bauer, M, Hamilton, J, Binder, F, Nar, H, Zeeb, M.
Deposit date:2021-02-23
Release date:2021-09-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain.
J.Med.Chem., 64, 2021
7NM4
DownloadVisualize
BU of 7nm4 by Molmil
Solution structure of MLKL executioner domain in complex with a fragment
Descriptor: (~{S})-1~{H}-benzimidazol-2-yl-(4-propan-2-ylphenyl)methanol, Mixed lineage kinase domain-like protein
Authors:Ruebbelke, M, Bauer, M, Hamilton, J, Binder, F, Nar, H, Zeeb, M.
Deposit date:2021-02-23
Release date:2021-09-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain.
J.Med.Chem., 64, 2021
7NM2
DownloadVisualize
BU of 7nm2 by Molmil
Solution structure of MLKL executioner domain in complex with a fragment
Descriptor: 2-[(~{S})-methoxy-(4-propan-2-ylphenyl)methyl]-3~{H}-benzimidazole-5-carboxylic acid, Mixed lineage kinase domain-like protein
Authors:Ruebbelke, M, Bauer, M, Hamilton, J, Binder, F, Nar, H, Zeeb, M.
Deposit date:2021-02-23
Release date:2021-09-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain.
J.Med.Chem., 64, 2021
6ZPR
DownloadVisualize
BU of 6zpr by Molmil
Solution structure of MLKL executioner domain in complex with a covalent inhibitor
Descriptor: 7-(2-methoxyethoxymethyl)-1,3-dimethyl-purine-2,6-dione, Mixed lineage kinase domain-like protein,Mixed lineage kinase domain-like protein
Authors:Ruebbelke, M, Bauer, M, Hamilton, J, Binder, F, Nar, H, Zeeb, M.
Deposit date:2020-07-09
Release date:2020-12-16
Last modified:2021-01-06
Method:SOLUTION NMR
Cite:Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis.
Proc.Natl.Acad.Sci.USA, 117, 2020
3OD1
DownloadVisualize
BU of 3od1 by Molmil
The crystal structure of an ATP phosphoribosyltransferase regulatory subunit/histidyl-tRNA synthetase from Bacillus halodurans C
Descriptor: ATP phosphoribosyltransferase regulatory subunit, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER
Authors:Tan, K, Bigelow, L, Hamilton, J, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-08-10
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:The crystal structure of aATP phosphoribosyltransferase regulatory subunit/histidyl-tRNA synthetase from Bacillus halodurans C
To be Published
3OOS
DownloadVisualize
BU of 3oos by Molmil
The structure of an alpha/beta fold family hydrolase from Bacillus anthracis str. Sterne
Descriptor: Alpha/beta hydrolase family protein, GLYCEROL, SULFATE ION, ...
Authors:Fan, Y, Tan, K, Bigelow, L, Hamilton, J, Li, H, Zhou, Y, Clancy, S, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-08-31
Release date:2010-11-10
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The structure of an alpha/beta fold family hydrolase from Bacillus anthracis str. Sterne
To be Published
4U2X
DownloadVisualize
BU of 4u2x by Molmil
Ebola virus VP24 in complex with Karyopherin alpha 5 C-terminus
Descriptor: CHLORIDE ION, Importin subunit alpha-6, Membrane-associated protein VP24
Authors:Xu, W, Leung, D, Borek, D, Amarasinghe, G.
Deposit date:2014-07-18
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.153 Å)
Cite:Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1.
Cell Host Microbe, 16, 2014
6ZLE
DownloadVisualize
BU of 6zle by Molmil
Solution structure of unliganded MLKL executioner domain
Descriptor: Mixed lineage kinase domain-like protein
Authors:Ruebbelke, M, Bauer, M, Nar, H, Zeeb, M.
Deposit date:2020-06-30
Release date:2020-12-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZVO
DownloadVisualize
BU of 6zvo by Molmil
Crystal structure of unliganded MLKL executioner domain
Descriptor: BROMIDE ION, CHLORIDE ION, Mixed lineage kinase domain-like protein
Authors:Fiegen, D, Bauer, M, Nar, H.
Deposit date:2020-07-27
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.371 Å)
Cite:Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZZ1
DownloadVisualize
BU of 6zz1 by Molmil
Crystal structure of MLKL executioner domain in complex with a covalent inhibitor
Descriptor: 7-(2-methoxyethoxymethyl)-1,3-dimethyl-purine-2,6-dione, Mixed lineage kinase domain-like protein
Authors:Fiegen, D, Bauer, M, Nar, H.
Deposit date:2020-08-03
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis.
Proc.Natl.Acad.Sci.USA, 117, 2020

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon