Author results

1UW3
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THE CRYSTAL STRUCTURE OF THE GLOBULAR DOMAIN OF SHEEP PRION PROTEIN
Descriptor:PRION PROTEIN, GLUTATHIONE, PHOSPHATE ION
Authors:Haire, L.F., Whyte, S.M., Vasisht, N., Gill, A.C., Verma, C., Dodson, E.J., Dodson, G.G., Bayley, P.M.
Deposit date:2004-01-29
Release date:2004-03-25
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Crystal Structure of the Globular Domain of Sheep Prion Protein
J.Mol.Biol., 336, 2004
1EYV
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THE CRYSTAL STRUCTURE OF NUSB FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG, PHOSPHATE ION
Authors:Gopal, B., Haire, L.F., Cox, R.A., Colston, M.J., Major, S., Brannigan, J.A., Smerdon, S.J., Dodson, G.G., TB Structural Genomics Consortium (TBSGC)
Deposit date:2000-05-09
Release date:2000-05-18
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of NusB from Mycobacterium tuberculosis.
Nat.Struct.Biol., 7, 2000
4CFH
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STRUCTURE OF AN ACTIVE FORM OF MAMMALIAN AMPK
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2013-11-18
Release date:2013-12-25
Last modified:2014-01-08
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
1GXC
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FHA DOMAIN FROM HUMAN CHK2 KINASE IN COMPLEX WITH A SYNTHETIC PHOSPHOPEPTIDE
Descriptor:SERINE/THREONINE-PROTEIN KINASE CHK2, SYNTHETIC PHOSPHOPEPTIDE
Authors:Li, J., Williams, B.L., Haire, L.F., Goldberg, M., Wilker, E., Durocher, D., Yaffe, M.B., Jackson, S.P., Smerdon, S.J.
Deposit date:2002-04-02
Release date:2002-06-13
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
Mol.Cell, 9, 2002
1K0R
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS NUSA
Descriptor:NusA, SULFATE ION
Authors:Gopal, B., Haire, L.F., Gamblin, S.J., Dodson, E.J., Lane, A.N., Papavinasasundaram, K.G., Colston, M.J., Dodson, G., TB Structural Genomics Consortium (TBSGC)
Deposit date:2001-09-20
Release date:2001-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the transcription elongation/anti-termination factor NusA from Mycobacterium tuberculosis at 1.7 A resolution.
J.Mol.Biol., 314, 2001
1RU7
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1934 HUMAN H1 HEMAGGLUTININ
Descriptor:hemagglutinin
Authors:Skehel, J.J., Gamblin, S.J., Haire, L.F., Russell, R.J., Stevens, D.J., Xiao, B., Ha, Y., Vasisht, N., Steinhauer, D.A., Daniels, R.S.
Deposit date:2003-12-11
Release date:2004-03-30
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1RUY
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1930 SWINE H1 HEMAGGLUTININ
Descriptor:hemagglutinin, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE
Authors:Skehel, J.J., Gamblin, S.J., Haire, L.F., Russell, R.J., Stevens, D.J., Xiao, B., Ha, Y., Vasisht, N., Steinhauer, D.A., Daniels, R.S.
Deposit date:2003-12-12
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1RUZ
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1918 H1 HEMAGGLUTININ
Descriptor:hemagglutinin, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE
Authors:Skehel, J.J., Gamblin, S.J., Haire, L.F., Russell, R.J., Stevens, D.J., Xiao, B., Ha, Y., Vasisht, N., Steinhauer, D.A., Daniels, R.S.
Deposit date:2003-12-12
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1RV0
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1930 SWINE H1 HEMAGGLUTININ COMPLEXED WITH LSTA
Descriptor:hemagglutinin, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID
Authors:Skehel, J.J., Gamblin, S.J., Haire, L.F., Russell, R.J., Stevens, D.J., Xiao, B., Ha, Y., Vasisht, N., Steinhauer, D.A., Daniels, R.S.
Deposit date:2003-12-12
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1RVT
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1930 H1 HEMAGGLUTININ IN COMPLEX WITH LSTC
Descriptor:hemagglutinin, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Skehel, J.J., Gamblin, S.J., Haire, L.F., Russell, R.J., Stevens, D.J., Xiao, B., Ha, Y., Vasisht, N., Steinhauer, D.A., Daniels, R.S.
Deposit date:2003-12-15
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1RVX
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1934 H1 HEMAGGLUTININ IN COMPLEX WITH LSTA
Descriptor:hemagglutinin, Hemagglutinin, O-SIALIC ACID, ...
Authors:Gamblin, S.J., Haire, L.F., Russell, R.J., Stevens, D.J., Xiao, B., Ha, Y., Vasisht, N., Steinhauer, D.A., Daniels, R.S., Elliot, A., Wiley, D.C., Skehel, J.J.
Deposit date:2003-12-15
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1RVZ
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1934 H1 HEMAGGLUTININ IN COMPLEX WITH LSTC
Descriptor:hemagglutinin, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Gamblin, S.J., Haire, L.F., Russell, R.J., Stevens, D.J., Xiao, B., Ha, Y., Vasisht, N., Steinhauer, D.A., Daniels, R.S., Elliot, A., Wiley, D.C., Skehel, J.J.
Deposit date:2003-12-15
Release date:2004-03-30
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1T15
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CRYSTAL STRUCTURE OF THE BRCA1 BRCT DOMAINS IN COMPLEX WITH THE PHOSPHORYLATED INTERACTING REGION FROM BACH1 HELICASE
Descriptor:Breast cancer type 1 susceptibility protein, BRCA1 interacting protein C-terminal helicase 1
Authors:Clapperton, J.A., Manke, I.A., Lowery, D.M., Ho, T., Haire, L.F., Yaffe, M.B., Smerdon, S.J.
Deposit date:2004-04-15
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
Nat.Struct.Mol.Biol., 11, 2004
1TI8
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H7 HAEMAGGLUTININ
Descriptor:hemagglutinin, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ALPHA-D-MANNOSE, ...
Authors:Russell, R.J., Gamblin, S.J., Haire, L.F., Stevens, D.J., Xaio, B., Ha, Y., Skehel, J.J.
Deposit date:2004-06-02
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:H1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes.
Virology, 325, 2004
1U7K
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STRUCTURE OF A HEXAMERIC N-TERMINAL DOMAIN FROM MURINE LEUKEMIA VIRUS CAPSID
Descriptor:Gag polyprotein
Authors:Mortuza, G.B., Haire, L.F., Stevens, A., Smerdon, S.J., Stoye, J.P., Taylor, I.A.
Deposit date:2004-08-04
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:High-resolution structure of a retroviral capsid hexameric amino-terminal domain.
Nature, 431, 2004
2HT5
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N8 NEURAMINIDASE
Descriptor:Neuraminidase, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, CALCIUM ION
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-25
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HT7
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N8 NEURAMINIDASE IN OPEN COMPLEX WITH OSELTAMIVIR
Descriptor:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-25
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HT8
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N8 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR
Descriptor:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-25
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTQ
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N8 NEURAMINIDASE IN COMPLEX WITH ZANAMIVIR
Descriptor:Neuraminidase, ZANAMIVIR
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTR
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N8 NEURAMINIDASE IN COMPLEX WITH DANA
Descriptor:Neuraminidase, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTU
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N8 NEURAMINIDASE IN COMPLEX WITH PERAMIVIR
Descriptor:Neuraminidase, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTV
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N4 NEURAMINIDASE
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTW
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N4 NEURAMINIDASE IN COMPLEX WITH DANA
Descriptor:Neuraminidase, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTY
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N1 NEURAMINIDASE
Descriptor:Neuraminidase, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, CALCIUM ION, ...
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HU0
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N1 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR 1
Descriptor:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006