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2D1E
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CRYSTAL STRUCTURE OF PCYA-BILIVERDIN COMPLEX
Descriptor:Phycocyanobilin:ferredoxin oxidoreductase, SODIUM ION, BILIVERDINE IX ALPHA
Authors:Hagiwara, Y., Sugishima, M., Takahashi, Y., Fukuyama, K.
Deposit date:2005-08-17
Release date:2006-01-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Crystal structure of phycocyanobilin:ferredoxin oxidoreductase in complex with biliverdin IXalpha, a key enzyme in the biosynthesis of phycocyanobilin
Proc.Natl.Acad.Sci.Usa, 103, 2006
2DKE
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CRYSTAL STRUCTURE OF SUBSTRATE-FREE FORM OF PCYA
Descriptor:Phycocyanobilin:ferredoxin oxidoreductase, CHLORIDE ION
Authors:Hagiwara, Y., Sugishima, M., Takahashi, Y., Fukuyama, K.
Deposit date:2006-04-10
Release date:2006-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Induced-fitting and electrostatic potential change of PcyA upon substrate binding demonstrated by the crystal structure of the substrate-free form
Febs Lett., 580, 2006
3I8U
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CRYSTAL STRUCTURE OF PCYA-181,182-DIHYDROBILIVERDIN COMPLEX
Descriptor:Phycocyanobilin:ferredoxin oxidoreductase, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(Z)-(4-ethyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Authors:Hagiwara, Y., Sugishima, M., Fukuyama, K.
Deposit date:2009-07-10
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural insights into vinyl reduction regiospecificity of phycocyanobilin:ferredoxin oxidoreductase (PcyA).
To be Published
3I94
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CRYSTAL STRUCTURE OF PCYA-BILIVERDIN XIII ALPHA COMPLEX
Descriptor:Phycocyanobilin:ferredoxin oxidoreductase, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, SULFATE ION
Authors:Hagiwara, Y., Sugishima, M., Fukuyama, K.
Deposit date:2009-07-10
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Structural insights into vinyl reduction regiospecificity of phycocyanobilin:ferredoxin oxidoreductase (PcyA).
to be published
3I95
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CRYSTAL STRUCTURE OF E76Q MUTANT PCYA-BILIVERDIN COMPLEX
Descriptor:Phycocyanobilin:ferredoxin oxidoreductase, BILIVERDINE IX ALPHA
Authors:Hagiwara, Y., Sugishima, M., Fukuyama, K.
Deposit date:2009-07-10
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insights into vinyl reduction regiospecificity of phycocyanobilin:ferredoxin oxidoreductase (PcyA).
To be Published
5B4H
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CRYSTAL STRUCTURE OF I86D MUTANT OF PHYCOCYANOBILIN:FERREDOXIN OXIDOREDUCTASE IN COMPLEX WITH BILIVERDIN (DATA 1)
Descriptor:Phycocyanobilin:ferredoxin oxidoreductase, BILIVERDINE IX ALPHA
Authors:Hagiwara, Y., Wada, K., Irikawa, T., Unno, M., Fukuyama, K., Sugishima, M.
Deposit date:2016-04-04
Release date:2017-03-15
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Atomic-resolution structure of the phycocyanobilin:ferredoxin oxidoreductase I86D mutant in complex with fully protonated biliverdin
FEBS Lett., 590, 2016
5B4I
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CRYSTAL STRUCTURE OF I86D MUTANT OF PHYCOCYANOBILIN:FERREDOXIN OXIDOREDUCTASE IN COMPLEX WITH BILIVERDIN (DATA 2)
Descriptor:Phycocyanobilin:ferredoxin oxidoreductase, BILIVERDINE IX ALPHA
Authors:Hagiwara, Y., Wada, K., Irikawa, T., Unno, M., Fukuyama, K., Sugishima, M.
Deposit date:2016-04-04
Release date:2017-03-15
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Atomic-resolution structure of the phycocyanobilin:ferredoxin oxidoreductase I86D mutant in complex with fully protonated biliverdin
FEBS Lett., 590, 2016
5B4J
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CRYSTAL STRUCTURE OF I86D MUTANT OF PHYCOCYANOBILIN:FERREDOXIN OXIDOREDUCTASE IN COMPLEX WITH BILIVERDIN (DATA 3)
Descriptor:Phycocyanobilin:ferredoxin oxidoreductase, BILIVERDINE IX ALPHA
Authors:Hagiwara, Y., Wada, K., Irikawa, T., Unno, M., Fukuyama, K., Sugishima, M.
Deposit date:2016-04-04
Release date:2017-03-15
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Atomic-resolution structure of the phycocyanobilin:ferredoxin oxidoreductase I86D mutant in complex with fully protonated biliverdin
FEBS Lett., 590, 2016
3AJG
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CRYSTAL STRUCTURE OF PCYA V225D-BILIVERDIN IX ALPHA COMPLEX
Descriptor:Phycocyanobilin:ferredoxin oxidoreductase, BILIVERDINE IX ALPHA
Authors:Wada, K., Hagiwara, Y., Fukuyama, K.
Deposit date:2010-06-05
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:One residue substitution in PcyA leads to unexpected changes in tetrapyrrole substrate binding.
Biochem.Biophys.Res.Commun., 402, 2010
3AJH
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CRYSTAL STRUCTURE OF PCYA V225D-BILIVERDIN XIII ALPHA COMPLEX
Descriptor:Phycocyanobilin:ferredoxin oxidoreductase, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Authors:Wada, K., Hagiwara, Y., Fukuyama, K.
Deposit date:2010-06-05
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:One residue substitution in PcyA leads to unexpected changes in tetrapyrrole substrate binding.
Biochem.Biophys.Res.Commun., 402, 2010
1WOV
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CRYSTAL STRUCTURE OF HEME OXYGENASE-2 FROM SYNECHOCYSTIS SP. PCC 6803 IN COMPLEX WITH HEME
Descriptor:Heme oxygenase 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M., Hagiwara, Y., Zhang, X., Yoshida, T., Migita, C.T., Fukuyama, K.
Deposit date:2004-08-26
Release date:2005-03-22
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of dimeric heme oxygenase-2 from Synechocystis sp. PCC 6803 in complex with heme.
Biochemistry, 44, 2005
1WOW
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CRYSTAL STRUCTURE OF HEME OXYGENASE-2 FROM SYNECHOCYSTIS SP. PCC 6803 COMPLEXED WITH HEME IN FERROUS FORM
Descriptor:Heme oxygenase 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M., Hagiwara, Y., Zhang, X., Yoshida, T., Migita, C.T., Fukuyama, K.
Deposit date:2004-08-26
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of dimeric heme oxygenase-2 from Synechocystis sp. PCC 6803 in complex with heme.
Biochemistry, 44, 2005
1WOX
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CRYSTAL STRUCTURE OF HEME OXYGENASE-2 FROM SYNECHOCYSTIS SP. PCC 6803 IN COMPLEX WITH HEME AND NO
Descriptor:Heme oxygenase 2, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE
Authors:Sugishima, M., Hagiwara, Y., Zhang, X., Yoshida, T., Migita, C.T., Fukuyama, K.
Deposit date:2004-08-26
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of dimeric heme oxygenase-2 from Synechocystis sp. PCC 6803 in complex with heme.
Biochemistry, 44, 2005
4QCD
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NEUTRON CRYSTAL STRUCTURE OF PHYCOCYANOBILIN:FERREDOXIN OXIDOREDUCTASE IN COMPLEX WITH BILIVERDIN IXALPHA AT ROOM TEMPERATURE.
Descriptor:Phycocyanobilin:ferredoxin oxidoreductase, BILIVERDINE IX ALPHA, trideuteriooxidanium
Authors:Unno, M., Ishikawa-Suto, K., Ishihara, M., Hagiwara, Y., Sugishima, M., Wada, K., Fukuyama, K.
Deposit date:2014-05-10
Release date:2015-04-29
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.932 Å), NEUTRON DIFFRACTION
Cite:Insights into the Proton Transfer Mechanism of a Bilin Reductase PcyA Following Neutron Crystallography.
J. Am. Chem. Soc., 137, 2015
5B3T
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CRYSTAL STRUCTURE OF APO-FORM BILIVERDIN REDUCTASE FROM SYNECHOCYSTIS SP. PCC 6803
Descriptor:Biliverdin reductase, PHOSPHATE ION
Authors:Takao, H., Wada, K.
Deposit date:2016-03-12
Release date:2017-02-15
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:A substrate-bound structure of cyanobacterial biliverdin reductase identifies stacked substrates as critical for activity
Nat Commun, 8, 2017
5B3U
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CRYSTAL STRUCTURE OF BILIVERDIN REDUCTASE IN COMPLEX WITH NADP+ FROM SYNECHOCYSTIS SP. PCC 6803
Descriptor:Biliverdin reductase, PHOSPHATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Takao, H., Wada, K.
Deposit date:2016-03-13
Release date:2017-02-15
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:A substrate-bound structure of cyanobacterial biliverdin reductase identifies stacked substrates as critical for activity
Nat Commun, 8, 2017
5B3V
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CRYSTAL STRUCTURE OF BILIVERDIN REDUCTASE IN COMPLEX WITH BILIVERDIN AND NADP+ FROM SYNECHOCYSTIS SP. PCC 6803
Descriptor:Biliverdin reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, BILIVERDINE IX ALPHA
Authors:Takao, H., Wada, K.
Deposit date:2016-03-13
Release date:2017-02-15
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:A substrate-bound structure of cyanobacterial biliverdin reductase identifies stacked substrates as critical for activity
Nat Commun, 8, 2017
5B1S
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CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI SPERMIDINE SYNTHASE IN COMPLEX WITH 2-(2-FLUOROPHENYL)ETHANAMINE
Descriptor:Spermidine synthase, putative, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, ...
Authors:Amano, Y., Tateishi, Y.
Deposit date:2015-12-17
Release date:2016-12-21
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease
Sci Rep, 7, 2017
5Y4P
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CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI SPERMIDINE SYNTHASE IN COMPLEX WITH 5-METHOXY-2-(5-METHYL-4,5-DIHYDRO-1H-IMIDAZOL-2-YL)PHENOL
Descriptor:Spermidine synthase, putative, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, ...
Authors:Amano, Y., Tateishi, Y.
Deposit date:2017-08-04
Release date:2018-08-08
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Discovering a hidden allosteric binding site by combining molecular simulations and X-ray crystallography
To Be Published
5Y4Q
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CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI SPERMIDINE SYNTHASE IN COMPLEX WITH N-(4-METHOXYPHENYL)QUINOLIN-4-AMINE
Descriptor:Spermidine synthase, putative, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, ...
Authors:Amano, Y., Tateishi, Y.
Deposit date:2017-08-04
Release date:2018-08-08
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Discovering a hidden allosteric binding site by combining molecular simulations and X-ray crystallography
To Be Published