Author results

2F4S
  • Download 2f4s
  • View 2f4s
Molmil generated image of 2f4s
A-SITE RNA IN COMPLEX WITH NEAMINE
Descriptor:5'-R(P*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', (2R,3S,4R,5R,6R)-6-((1R,2R,3S,4R,6S)-4,6-DIAMINO-2,3-DIHYDROXYCYCLOHEXYLOXY)-5-AMINO-2-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-3,4-DIOL
Authors:Murray, J.B., Meroueh, S.O., Russell, R.J., Lentzen, G., Haddad, J., Mobashery, S.
Deposit date:2005-11-24
Release date:2006-05-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site
Chem.Biol., 13, 2006
2F4T
  • Download 2f4t
  • View 2f4t
Molmil generated image of 2f4t
ASITE RNA + DESIGNER ANTIBIOTIC
Descriptor:5'-R(*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', 5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', (2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE
Authors:Murray, J.B., Meroueh, S.O., Russell, R.J., Lentzen, G., Haddad, J., Mobashery, S.
Deposit date:2005-11-24
Release date:2006-05-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site
Chem.Biol., 13, 2006
2F4U
  • Download 2f4u
  • View 2f4u
Molmil generated image of 2f4u
ASITE RNA + DESIGNER ANTIBIOTIC
Descriptor:5'-R(*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', (2R)-4-AMINO-N-((1R,2S,3R,4R,5S)-5-AMINO-4-[(2-AMINO-2-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-{2-[(3-AMINOPROPYL)AMINO]ETHOXY}-3-HYDROXYCYCLOHEXYL)-2-HYDROXYBUTANAMIDE
Authors:Murray, J.B., Meroueh, S.O., Russell, R.J., Lentzen, G., Haddad, J., Mobashery, S.
Deposit date:2005-11-24
Release date:2006-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site
Chem.Biol., 13, 2006
2F4V
  • Download 2f4v
  • View 2f4v
Molmil generated image of 2f4v
30S RIBOSOME + DESIGNER ANTIBIOTIC
Descriptor:16S ribosomal RNA, 5'-R(P*UP*UP*CP*U)-3', 30S ribosomal protein S2, ...
Authors:Murray, J.B., Meroueh, S.O., Russell, R.J., Lentzen, G., Haddad, J., Mobashery, S.
Deposit date:2005-11-24
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Interactions of designer antibiotics and the bacterial ribosome aminoacyl-tRNA site
Chem.Biol., 13, 2006
5I6J
  • Download 5i6j
  • View 5i6j
Molmil generated image of 5i6j
CRYSTAL STRUCTURE OF SRGAP2 F-BARX
Descriptor:SLIT-ROBO Rho GTPase-activating protein 2
Authors:Sporny, M., Guez-Haddad, J., Isupov, M.N., Opatowsky, Y.
Deposit date:2016-02-16
Release date:2017-03-08
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural History of Human SRGAP2 Proteins.
Mol. Biol. Evol., 34, 2017
5I6R
  • Download 5i6r
  • View 5i6r
Molmil generated image of 5i6r
CRYSTAL STRUCTURE OF SRGAP2 F-BARX WT FORM-1
Descriptor:SLIT-ROBO Rho GTPase-activating protein 2, D-MALATE, ACETATE ION, ...
Authors:Sporny, M., Guez-Haddad, J., Isupov, M.N., Opatowsky, Y.
Deposit date:2016-02-16
Release date:2017-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Basis for srGAP2 Membrane Interactions, and Antagonism by the Human Specific Paralog srGAP2C
To Be Published
5I7D
  • Download 5i7d
  • View 5i7d
Molmil generated image of 5i7d
CRYSTAL STRUCTURE OF SRGAP2 F-BARX WT FORM-2
Descriptor:SLIT-ROBO Rho GTPase-activating protein 2
Authors:Sporny, M., Guez-Haddad, J., Isupov, M.N., Opatowsky, Y.
Deposit date:2016-02-17
Release date:2017-08-30
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Structural Basis for srGAP2 Membrane Interactions, and Antagonism by the Human Specific Paralog srGAP2C
To Be Published
4RTT
  • Download 4rtt
  • View 4rtt
Molmil generated image of 4rtt
CYRSTAL STRUCTURE OF SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 2 FRAGMENT
Descriptor:SLIT-ROBO Rho GTPase-activating protein 2, SULFATE ION
Authors:Opatowsky, Y., Guez-Hadad, J.
Deposit date:2014-11-16
Release date:2015-11-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.
Structure, 23, 2015
4RUG
  • Download 4rug
  • View 4rug
Molmil generated image of 4rug
CYRSTAL STRUCTURE OF SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 2 FRAGMENT
Descriptor:SLIT-ROBO Rho GTPase-activating protein 2
Authors:Opatowsky, Y., Guez-Hadad, J.
Deposit date:2014-11-19
Release date:2015-11-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.
Structure, 23, 2015
5NOI
  • Download 5noi
  • View 5noi
Molmil generated image of 5noi
HUMAN ROBO2 EXTRACELLULAR DOMAINS 4-5
Descriptor:Roundabout homolog 2
Authors:Opatowsky, Y., Barak, R.
Deposit date:2017-04-12
Release date:2017-10-25
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Robo Ig4 Is a Dimerization Domain.
J. Mol. Biol., 429, 2017
1O9M
  • Download 1o9m
  • View 1o9m
Molmil generated image of 1o9m
THE COMPLEX OF A NOVEL ANTIBIOTIC WITH THE AMINOACYL SITE OF THE BACTERIAL RIBOSOME REVEALED BY X-RAY CRYSTALLOGRAPHY.
Descriptor:EUBACTERIAL A-SITE, O-2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSE, PAROMOMYCIN (RING 2), ...
Authors:Russell, R., Murray, J.B.
Deposit date:2002-12-17
Release date:2003-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Complex of a Designer Antibiotic with a Model Aminoacyl Site of the 30S Ribosomal Subunit Revealed by X-Ray Crystallography
J.Am.Chem.Soc., 125, 2003
6I9S
  • Download 6i9s
  • View 6i9s
Molmil generated image of 6i9s
HROBO2 EXTRACELLULAR DOMAINS 2-3
Descriptor:Roundabout homolog 2, SODIUM ION
Authors:Barak, R., Isupov, N.M., Opatowsky, Y.
Deposit date:2018-11-25
Release date:2019-03-13
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural Principles in Robo Activation and Auto-inhibition.
Cell, 177, 2019
6IAA
  • Download 6iaa
  • View 6iaa
Molmil generated image of 6iaa
HROBO2 ECTODOMAIN
Descriptor:Roundabout homolog 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Barak, R., Isupov, N.M., Opatowsky, Y.
Deposit date:2018-11-26
Release date:2019-03-13
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Principles in Robo Activation and Auto-inhibition.
Cell, 177, 2019