Author results

1YB3
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CONSERVED HYPOTHETICAL PROTEIN PFU-178653-001 FROM PYROCOCCUS FURIOSUS
Descriptor:hypothetical protein, UNKNOWN ATOM OR ION
Authors:Habel, J., Zhou, W., Chang, J., Zhao, M., Xu, H., Chen, L., Lee, D., Nguyen, D., Chang, S.-H., Horanyi, P., Florence, Q., Tempel, W., Lin, D., Zhang, H., Praissman, J., Jenney Jr., F.E., Adams, M.W.W., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-19
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conserved hypothetical protein Pfu-178653-001 from Pyrococcus furiosus
To be published
5UVM
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HIT FAMILY HYDROLASE FROM CLOSTRIDIUM THERMOCELLUM CTH-393
Descriptor:Histidine triad (HIT) protein, ZINC ION, UNKNOWN ATOM OR ION, ...
Authors:Habel, J., Tempel, W., Liu, Z.-J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2017-02-20
Release date:2017-04-05
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:HIT family hydrolase from Clostridium thermocellum Cth-393
To Be Published
2R9S
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C-JUN N-TERMINAL KINASE 3 WITH 3,5-DISUBSTITUTED QUINOLINE INHIBITOR
Descriptor:Mitogen-activated protein kinase 10, N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide, UNKNOWN ATOM OR ION, ...
Authors:Habel, J.
Deposit date:2007-09-13
Release date:2007-10-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:3,5-Disubstituted quinolines as novel c-Jun N-terminal kinase inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
1XMA
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STRUCTURE OF A TRANSCRIPTIONAL REGULATOR FROM CLOSTRIDIUM THERMOCELLUM CTH-833
Descriptor:Predicted transcriptional regulator, MERCURY (II) ION, UNKNOWN ATOM OR ION
Authors:Yang, H., Chen, L., Lee, D., Habel, J., Nguyen, J., Chang, S.-H., Kataeva, I., Xu, H., Chang, J., Zhao, M., Horanyi, P., Florence, Q., Zhou, W., Tempel, W., Lin, D., Praissman, J., Zhang, H., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Ljungdahl, L., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-10-01
Release date:2004-12-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structure of a transcriptional regulator from Clostridium thermocellum Cth-833
To be published
1XRG
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CONSERVED HYPOTHETICAL PROTEIN FROM CLOSTRIDIUM THERMOCELLUM CTH-2968
Descriptor:Putative translation initiation inhibitor, yjgF family, UNKNOWN ATOM OR ION
Authors:Zhao, M., Chang, J., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Zhou, W., Tempel, W., Lin, D., Zhang, H., Arendall III, W.B., Ljundahl, L., Liu, Z.-J., Rose, J., Richardson, J.S., Richardson, D.C., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-10-14
Release date:2004-12-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conserved hypothetical protein from Clostridium thermocellum Cth-2968
To be published
1YBX
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CONSERVED HYPOTHETICAL PROTEIN CTH-383 FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:Conserved hypothetical protein, UNKNOWN ATOM OR ION
Authors:Tempel, W., Chang, J., Zhao, M., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Zhou, W., Lin, D., Zhang, H., Ljundahl, L., Liu, Z.-J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-21
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conserved hypothetical protein Cth-383 from Clostridium thermocellum
To be published
1YBY
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CONSERVED HYPOTHETICAL PROTEIN CTH-95 FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:Translation elongation factor P, UNKNOWN ATOM OR ION
Authors:Zhao, M., Zhou, W., Chang, J., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Tempel, W., Lin, D., Zhang, H., Ljundahl, L., Liu, Z.-J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-21
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Conserved hypothetical protein Cth-95 from Clostridium thermocellum
To be published
1XG7
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CONSERVED HYPOTHETICAL PROTEIN PFU-877259-001 FROM PYROCOCCUS FURIOSUS
Descriptor:hypothetical protein
Authors:Chang, J., Zhao, M., Horanyi, P., Xu, H., Yang, H., Liu, Z.-J., Chen, L., Zhou, W., Habel, J., Tempel, W., Lee, D., Lin, D., Chang, S.-H., Eneh, J.C., Hopkins, R.C., Jenney Jr., F.E., Lee, H.-S., Li, T., Poole II, F.L., Shah, C., Sugar, F.J., Chen, C.-Y., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Rose, J.P., Adams, M.W.W., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-09-16
Release date:2004-11-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus
To be published
1Y6J
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L-LACTATE DEHYDROGENASE FROM CLOSTRIDIUM THERMOCELLUM CTH-1135
Descriptor:L-lactate dehydrogenase
Authors:Chen, L., Yang, H., Kataeva, I., Chen, L.R., Tempel, W., Lee, D., Habel, J., Zhou, W., Lin, D., Ljungdahl, L., Liu, Z.-J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-06
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:L-Lactate Dehydrogenase from Clostridium Thermocellum Cth-1135
To be Published
1Y80
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STRUCTURE OF A CORRINOID (FACTOR IIIM)-BINDING PROTEIN FROM MOORELLA THERMOACETICA
Descriptor:Predicted cobalamin binding protein, CO-5-METHOXYBENZIMIDAZOLYLCOBAMIDE, UNKNOWN ATOM OR ION
Authors:Liu, Z.-J., Fu, Z.-Q., Tempel, W., Das, A., Habel, J., Zhou, W., Chang, J., Chen, L., Lee, D., Nguyen, D., Chang, S.-H., Ljungdahl, L., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-10
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of a corrinoid (factor IIIm)-binding protein from Moorella thermoacetica
To be published
1Y81
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CONSERVED HYPOTHETICAL PROTEIN PFU-723267-001 FROM PYROCOCCUS FURIOSUS
Descriptor:conserved hypothetical protein, THIOCYANATE ION, COENZYME A, ...
Authors:Zhao, M., Chang, J., Habel, J., Xu, H., Chen, L., Lee, D., Nguyen, D., Chang, S.-H., Horanyi, P., Florence, Q., Tempel, W., Zhou, W., Lin, D., Zhang, H., Praissman, J., Jenney Jr., F.E., Adams, M.W.W., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-10
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Conserved hypothetical protein Pfu-723267-001 from Pyrococcus furiosus
To be published
1Y82
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CONSERVED HYPOTHETICAL PROTEIN PFU-367848-001 FROM PYROCOCCUS FURIOSUS
Descriptor:hypothetical protein, UNKNOWN ATOM OR ION
Authors:Horanyi, P., Tempel, W., Habel, J., Chen, L., Lee, D., Nguyen, D., Chang, S.-H., Florence, Q., Zhou, W., Lin, D., Zhang, H., Praissman, J., Jenney Jr., F.E., Adams, M.W.W., Liu, Z.-J., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-10
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conserved hypothetical protein Pfu-367848-001 from Pyrococcus furiosus
To be published
1YBZ
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CONSERVED HYPOTHETICAL PROTEIN FROM PYROCOCCUS FURIOSUS PFU-1581948-001
Descriptor:chorismate mutase, UNKNOWN ATOM OR ION
Authors:Lee, D., Chen, L., Nguyen, D., Dillard, B.D., Tempel, W., Habel, J., Zhou, W., Chang, S.-H., Kelley, L.-L.C., Liu, Z.-J., Lin, D., Zhang, H., Praissman, J., Bridger, S., Eneh, J.C., Hopkins, R.C., Jenney Jr., F.E., Lee, H.-S., Li, T., Poole II, F.L., Shah, C., Sugar, F.J., Adams, M.W.W., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-21
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Conserved hypothetical protein from Pyrococcus furiosus Pfu-1581948-001
To be published
1YCY
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CONSERVED HYPOTHETICAL PROTEIN PFU-1806301-001 FROM PYROCOCCUS FURIOSUS
Descriptor:Conserved hypothetical protein
Authors:Huang, L., Liu, Z.-J., Lee, D., Tempel, W., Chang, J., Zhao, M., Habel, J., Xu, H., Chen, L., Nguyen, D., Chang, S.-H., Horanyi, P., Florence, Q., Zhou, W., Lin, D., Zhang, H., Praissman, J., Jenney Jr., F.E., Adams, M.W.W., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-23
Release date:2005-02-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conserved hypothetical protein Pfu-1806301-001 from Pyrococcus furiosus
To be published
1YD7
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CONSERVED HYPOTHETICAL PROTEIN PFU-1647980-001 FROM PYROCOCCUS FURIOSUS
Descriptor:2-keto acid:ferredoxin oxidoreductase subunit alpha, UNKNOWN ATOM OR ION
Authors:Horanyi, P., Florence, Q., Zhou, W., Chang, J., Zhao, M., Habel, J., Xu, H., Chen, L., Lee, D., Nguyen, D., Chang, S.-H., Tempel, W., Lin, D., Zhang, H., Praissman, J., Jenney Jr., F.E., Adams, M.W.W., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-23
Release date:2005-02-08
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conserved hypothetical protein Pfu-1647980-001 from Pyrococcus furiosus
To be published
1ZGH
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METHIONYL-TRNA FORMYLTRANSFERASE FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:Methionyl-tRNA formyltransferase, UNKNOWN ATOM OR ION
Authors:Yang, H., Kataeva, I., Xu, H., Zhao, M., Chang, J., Liu, Z., Chen, L., Tempel, W., Habel, J., Zhou, W., Lee, D., Lin, D., Chang, S., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Rose, J.P., Wang, B., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-04-21
Release date:2005-05-03
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Methionyl-tRNA formyltransferase from Clostridium thermocellum
To be published
2FZF
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HYPOTHETICAL PROTEIN PFU-1136390-001 FROM PYROCOCCUS FURIOSUS
Descriptor:hypothetical protein
Authors:Fu, Z.-Q., Liu, Z.-J., Lee, D., Kelley, L., Chen, L., Tempel, W., Shah, N., Horanyi, P., Lee, H.S., Habel, J., Dillard, B.D., Nguyen, D., Chang, S.-H., Zhang, H., Chang, J., Sugar, F.J., Poole, F.L., Jenney Jr., F.E., Adams, M.W.W., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2006-02-09
Release date:2006-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Hypothetical Protein Pfu-1136390-001 From Pyrococcus furiosus
To be published
1XI3
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THIAMINE PHOSPHATE PYROPHOSPHORYLASE FROM PYROCOCCUS FURIOSUS PFU-1255191-001
Descriptor:Thiamine phosphate pyrophosphorylase, SULFATE ION, UNKNOWN ATOM OR ION, ...
Authors:Zhou, W., Chen, L., Tempel, W., Liu, Z.-J., Habel, J., Lee, D., Lin, D., Chang, S.-H., Dillard, B.D., Eneh, J.C., Hopkins, R.C., Jenney Jr., F.E., Kelley, L.-L.C., Lee, H.-S., Li, T., Poole II, F.L., Shah, C., Sugar, F.J., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Rose, J.P., Adams, M.W.W., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-09-21
Release date:2004-09-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001
To be published
1XX7
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CONSERVED HYPOTHETICAL PROTEIN FROM PYROCOCCUS FURIOSUS PFU-403030-001
Descriptor:oxetanocin-like protein, NICKEL (II) ION, UNKNOWN ATOM OR ION
Authors:Chen, L., Tempel, W., Habel, J., Zhou, W., Nguyen, D., Chang, S.-H., Lee, D., Kelley, L.-L.C., Dillard, B.D., Liu, Z.-J., Bridger, S., Eneh, J.C., Hopkins, R.C., Jenney Jr, F.E., Lee, H.-S., Li, T., Poole II, F.L., Shah, C., Sugar, F.J., Adams, M.W.W., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-11-04
Release date:2004-12-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.261 Å)
Cite:Conserved hypothetical protein from Pyrococcus furiosus Pfu-403030-001
To be published
1ZTD
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HYPOTHETICAL PROTEIN PFU-631545-001 FROM PYROCOCCUS FURIOSUS
Descriptor:Hypothetical Protein Pfu-631545-001
Authors:Fu, Z.-Q., Horanyi, P., Florence, Q., Liu, Z.-J., Chen, L., Lee, D., Habel, J., Xu, H., Nguyen, D., Chang, S.-H., Zhou, W., Zhang, H., Jenney Jr., F.E., Sha, B., Adams, M.W.W., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-05-26
Release date:2005-06-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hypothetical Protein Pfu-631545-001 From Pyrococcus furiosus
To be Published
3KVX
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JNK3 BOUND TO AMINOPYRIMIDINE INHIBITOR, SR-3562
Descriptor:Mitogen-activated protein kinase 10, N-[(2Z)-4-(3-fluoro-5-morpholin-4-ylphenyl)pyrimidin-2(1H)-ylidene]-4-(3-morpholin-4-yl-1H-1,2,4-triazol-1-yl)aniline
Authors:Habel, J.E., Laughlin, J.D., LoGrasso, P.
Deposit date:2009-11-30
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Synthesis, Biological Evaluation, X-ray Structure, and Pharmacokinetics of Aminopyrimidine c-jun-N-terminal Kinase (JNK) Inhibitors
J.Med.Chem., 53, 2010
3FI2
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CRYSTAL STRUCTURE OF JNK3 WITH AMINO-PYRAZOLE INHIBITOR, SR-3451
Descriptor:Mitogen-activated protein kinase 10, 3-{4-[(phenylcarbamoyl)amino]-1H-pyrazol-1-yl}-N-(3,4,5-trimethoxyphenyl)benzamide, 1,2-ETHANEDIOL
Authors:Habel, J.E.
Deposit date:2008-12-10
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38.
J.Biol.Chem., 284, 2009
3FI3
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CRYSTAL STRUCTURE OF JNK3 WITH INDAZOLE INHIBITOR, SR-3737
Descriptor:Mitogen-activated protein kinase 10, 3-{5-[(2-fluorophenyl)amino]-1H-indazol-1-yl}-N-(3,4,5-trimethoxyphenyl)benzamide, 1,2-ETHANEDIOL
Authors:Habel, J.E., Duckett, D., LoGrasso, P.
Deposit date:2008-12-10
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38.
J.Biol.Chem., 284, 2009
3FV8
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JNK3 BOUND TO PIPERAZINE AMIDE INHIBITOR, SR2774.
Descriptor:Mitogen-activated protein kinase 10, 5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide, 1,2-ETHANEDIOL
Authors:Habel, J.E.
Deposit date:2009-01-15
Release date:2009-04-07
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
3H87
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RV0301 RV0300 TOXIN ANTITOXIN COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Putative uncharacterized protein, GLYCEROL, MAGNESIUM ION, ...
Authors:Min, A., Sawaya, M.R., Cascio, D., Eisenberg, D., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2009-04-28
Release date:2009-05-05
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg(2+) ion in the active site and a putative RNA-binding site.
Protein Sci., 21, 2012