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5AEB
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CRYSTAL STRUCTURE OF THE CLASS B3 DI-ZINC METALLO-BETA-LACTAMASE LRA- 12 FROM AN ALASKAN SOIL METAGENOME.
Descriptor:LRA-12, ZINC ION, SULFATE ION, ...
Authors:Power, P., Herman, R., Kerff, F., Bouillenne, F., Rodriguez, M.M., Galleni, M., Handelsman, J., Gutkind, G., Charlier, P., Sauvage, E.
Deposit date:2015-08-27
Release date:2015-09-16
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure and kinetic analysis of the class B3 di-zinc metallo-beta-lactamase LRA-12 from an Alaskan soil metagenome.
PLoS ONE, 12, 2017
3ZNY
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CRYSTAL STRUCTURE OF THE CLASS A EXTENDED-SPECTRUM BETA-LACTAMASE CTX- M-96, A NATURAL D240G MUTANT DERIVED FROM CTX-M-12
Descriptor:CTX-M-12A ENZYME
Authors:Power, P., Herman, R., Bouillenne, F., Ghiglione, B., Rodriguez, M.M., Galleni, M., Gutkind, G., Charlier, P., Sauvage, E.
Deposit date:2013-02-18
Release date:2014-01-08
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural and Kinetic Insights Into the "Ceftazidimase" Behavior of the Extended-Spectrum Beta-Lactamase Ctx-M-96.
Biochemistry, 54, 2015
4D2O
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CRYSTAL STRUCTURE OF THE CLASS A EXTENDED-SPECTRUM BETA-LACTAMASE PER- 2
Descriptor:PER-2 BETA-LACTAMASE
Authors:Power, P., Herman, R., Ruggiero, M., Kerff, F., Galleni, M., Gutkind, G., Charlier, P., Sauvage, E.
Deposit date:2014-05-12
Release date:2014-05-21
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the Extended-Spectrum Beta-Lactamase Per- 2 and Insights Into the Role of Specific Residues in the Interaction with Beta-Lactams and Beta-Lactamase Inhibitors.
Antimicrob.Agents Chemother., 58, 2014
6BN3
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CTX-M-151 CLASS A EXTENDED-SPECTRUM BETA-LACTAMASE APO CRYSTAL STRUCTURE AT 1.3 ANGSTROM RESOLUTION.
Descriptor:Beta-lactamase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Power, P., Ghiglione, B., Rodriguez, M.M., Gutkind, G., Ishii, Y., Bonomo, R.A., Klinke, S.
Deposit date:2017-11-16
Release date:2018-11-21
Method:X-RAY DIFFRACTION (1.278 Å)
Cite:CTX-M-151 class A extended-spectrum beta-lactamase apo crystal structure at 1.3 Angstrom resolution.
To Be Published
6BPF
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CTX-M-151 CLASS A EXTENDED-SPECTRUM BETA-LACTAMASE CRYSTAL STRUCTURE IN COMPLEX WITH AVIBACTAM AT 1.32 ANGSTROM RESOLUTION.
Descriptor:Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide
Authors:Power, P., Ghiglione, B., Rodriguez, M.M., Gutkind, G., Ishii, Y., Bonomo, R.A., Klinke, S.
Deposit date:2017-11-23
Release date:2018-11-28
Method:X-RAY DIFFRACTION (1.318 Å)
Cite:CTX-M-151 class A extended-spectrum beta-lactamase crystal structure in complex with avibactam at 1.32 Angstrom resolution.
To Be Published
6D3G
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PER-2 CLASS A EXTENDED-SPECTRUM BETA-LACTAMASE CRYSTAL STRUCTURE IN COMPLEX WITH AVIBACTAM AT 2.4 ANGSTROM RESOLUTION
Descriptor:Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, TETRAETHYLENE GLYCOL
Authors:Power, P., Ruggiero, M., Gutkind, G., Bonomo, R., Klinke, S.
Deposit date:2018-04-16
Release date:2019-04-24
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:Structural Insights into the Inhibition of the Extended-Spectrum beta-Lactamase PER-2 by Avibactam.
Antimicrob.Agents Chemother., 63, 2019
6DGU
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PER-2 CLASS A EXTENDED-SPECTRUM BETA-LACTAMASE CRYSTAL STRUCTURE AT 2.69 ANGSTROM RESOLUTION
Descriptor:Beta-lactamase
Authors:Power, P., Ruggiero, M., Gutkind, G., Bonomo, R., Klinke, S.
Deposit date:2018-05-18
Release date:2019-05-22
Method:X-RAY DIFFRACTION (2.691 Å)
Cite:PER-2 class A extended-spectrum beta-lactamase crystal structure in complex with avibactam at 2.4 Angstrom resolution.
To be published
2Y91
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CRYSTAL STRUCTURE OF CLASS A BETA-LACTAMASE FROM BACILLUS LICHENIFORMIS BS3 WITH CLAVULANIC ACID
Descriptor:BETA-LACTAMASE, 5-HYDROXY-3-OXOPENTANOIC ACID, CITRIC ACID, ...
Authors:Power, P., Sauvage, E., Herman, R., Kerff, F., Charlier, P.
Deposit date:2011-02-11
Release date:2012-02-22
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel Fragments of Clavulanate Observed in the Structure of the Class a Beta-Lactamase from Bacillus Licheniformis Bs3.
J.Antimicrob.Chemother., 67, 2012
3ZNT
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CRYSTAL STRUCTURE OF OXA-24 CLASS D BETA-LACTAMASE WITH TAZOBACTAM
Descriptor:BETA-LACTAMASE, TAZOBACTAM INTERMEDIATE, SULFATE ION
Authors:Power, P., Sauvage, E., Herman, R., Kerff, F., Charlier, P.
Deposit date:2013-02-18
Release date:2014-01-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of Oxa-24 Beta-Lactamase Inhibited by Tazobactam
To be Published
4A5R
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CRYSTAL STRUCTURE OF CLASS A BETA-LACTAMASE FROM BACILLUS LICHENIFORMIS BS3 WITH TAZOBACTAM
Descriptor:BETA-LACTAMASE, TAZOBACTAM INTERMEDIATE, CITRIC ACID, ...
Authors:Power, P., Sauvage, E., Herman, R., Kerff, F., Charlier, P.
Deposit date:2011-10-28
Release date:2012-10-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Class a Beta-Lactamase from Bacillus Licheniformis Inhibited by Tazobactam
To be Published