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1BCG
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BU of 1bcg by Molmil
SCORPION TOXIN BJXTR-IT
Descriptor: TOXIN BJXTR-IT
Authors:Oren, D, Froy, O, Amit, E, Kleinberger-Doron, N, Gurevitz, M, Shaanan, B.
Deposit date:1998-04-29
Release date:1998-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An excitatory scorpion toxin with a distinctive feature: an additional alpha helix at the C terminus and its implications for interaction with insect sodium channels.
Structure, 6, 1998
1SEG
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BU of 1seg by Molmil
Crystal structure of a toxin chimera between Lqh-alpha-IT from the scorpion Leiurus quinquestriatus hebraeus and AAH2 from Androctonus australis hector
Descriptor: AAH2: LQH-ALPHA-IT (FACE) CHIMERIC TOXIN, NITRATE ION, PROPANOIC ACID, ...
Authors:Karbat, I, Frolow, F, Froy, O, Gilles, N, Cohen, L, Turkov, M, Gordon, D, Gurevitz, M.
Deposit date:2004-02-17
Release date:2004-08-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Molecular basis of the high insecticidal potency of scorpion alpha-toxins.
J.Biol.Chem., 279, 2004
2I61
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BU of 2i61 by Molmil
Depressant anti-insect neurotoxin, LqhIT2 from Leiurus quinquestriatus hebraeus
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, CARBON DIOXIDE, ...
Authors:Frolow, F, Gurevitz, M, Karbat, I, Turkov, M, Gordon, D.
Deposit date:2006-08-27
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity.
J.Mol.Biol., 366, 2007
1LQH
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BU of 1lqh by Molmil
INSECTICIDAL ALPHA SCORPION TOXIN ISOLATED FROM THE VENOM OF SCORPION LEIURUS QUINQUESTRIATUS HEBRAEUS, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: INSECT TOXIN ALPHA
Authors:Tugarinov, V, Kustanovich, I, Zilberberg, N, Gurevitz, M, Anglister, J.
Deposit date:1996-06-17
Release date:1997-03-12
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity.
Biochemistry, 36, 1997
1LQI
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BU of 1lqi by Molmil
INSECTICIDAL ALPHA SCORPION TOXIN ISOLATED FROM THE VENOM OF SCORPION LEIURUS QUINQUESTRIATUS HEBRAEUS, NMR, 29 STRUCTURES
Descriptor: INSECT TOXIN ALPHA
Authors:Tugarinov, V, Kustanovich, I, Zilberberg, N, Gurevitz, M, Anglister, J.
Deposit date:1996-06-17
Release date:1997-03-12
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structures of a highly insecticidal recombinant scorpion alpha-toxin and a mutant with increased activity.
Biochemistry, 36, 1997
6ZOI
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BU of 6zoi by Molmil
A lid blocking mechanism of a cone snail toxin revealed at the atomic level
Descriptor: Conknunitzin-C3 mutante
Authors:Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I.
Deposit date:2020-07-07
Release date:2021-07-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:A lid blocking mechanism of a cone snail toxin revealed at the atomic level
To Be Published
2YEO
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BU of 2yeo by Molmil
A39L mutation of scorpion toxin lqh-alpha-it
Descriptor: 1,2-ETHANEDIOL, ALPHA-INSECT TOXIN LQHAIT, CHLORIDE ION, ...
Authors:Frolow, F, Kahn, R, Gurevitz, M.
Deposit date:2011-03-28
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Crystal Structures of Scorpion Alpha-Toxinsmutants Reveal Conformational Constraints that Dictate Preference for Mammalian Brain Voltage-Gated Na- Channels
To be Published
6Q61
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BU of 6q61 by Molmil
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels
Descriptor: Kunitz-type conkunitzin-S1, SULFATE ION
Authors:Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E.
Deposit date:2018-12-10
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Pore-modulating toxins exploit inherent slow inactivation to block K+channels.
Proc.Natl.Acad.Sci.USA, 116, 2019
6Q6C
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BU of 6q6c by Molmil
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels
Descriptor: 1,2-ETHANEDIOL, Kunitz-type conkunitzin-S1, NITRATE ION, ...
Authors:Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E.
Deposit date:2018-12-10
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Pore-modulating toxins exploit inherent slow inactivation to block K+channels.
Proc.Natl.Acad.Sci.USA, 116, 2019
2ATB
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BU of 2atb by Molmil
Triple mutant 8D9D10V of scorpion toxin LQH-alpha-IT
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, NITRATE ION, ...
Authors:Kahn, R, Karbat, I, Gurevitz, M, Frolow, F.
Deposit date:2005-08-24
Release date:2006-09-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant
To be Published
2ASC
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BU of 2asc by Molmil
Scorpion toxin LQH-alpha-IT
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, ETHANOL, ...
Authors:Kahn, R, Karbat, I, Gurevitz, M, Frolow, F.
Deposit date:2005-08-23
Release date:2006-09-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant
To be Published
6YHT
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BU of 6yht by Molmil
A lid blocking mechanism of a cone snail toxin revealed at the atomic level
Descriptor: CITRIC ACID, Conk-C1, SULFATE ION
Authors:Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I.
Deposit date:2020-03-31
Release date:2021-04-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A Molecular Lid Mechanism of K + Channel Blocker Action Revealed by a Cone Peptide.
J.Mol.Biol., 433, 2021
6YHY
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BU of 6yhy by Molmil
A lid blocking mechanism of a cone snail toxin revealed at the atomic level
Descriptor: Conk-S1
Authors:Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I.
Deposit date:2020-03-31
Release date:2021-04-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A Molecular Lid Mechanism of K + Channel Blocker Action Revealed by a Cone Peptide.
J.Mol.Biol., 433, 2021

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