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4IG4
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CRYSTAL STRUCTURE OF SINGLE MUTANT THERMOSTABLE NPPASE (N86S) FROM GEOBACILLUS STEAROTHERMOPHILUS
Descriptor:Thermostable NPPase
Authors:Guo, Z., Wang, F., Huang, J., Qiu, R., Yang, Z., Wang, Y., Gong, W., Ji, C.
Deposit date:2012-12-16
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Crystal structure of thermostable NPPase from Geobacillus stearothermophilus
To be Published
1ZRK
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FACTOR XI COMPLEXED WITH 3-HYDROXYPROPYL 3-(7-AMIDINONAPHTHALENE-1-CARBOXAMIDO)BENZENESULFONATE
Descriptor:Coagulation factor XI, SULFATE ION, 3-HYDROXYPROPYL 3-[({7-[AMINO(IMINO)METHYL]-1-NAPHTHYL}AMINO)CARBONYL]BENZENESULFONATE
Authors:Guo, Z., Bannister, T., Noll, R., Jin, L., Rynkiewicz, M.J., Bibbins, F., Magee, S., Gorga, J., Babine, R., Strickler, J.
Deposit date:2005-05-19
Release date:2006-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Synthesis and Optimization of Potent and Selective Inhibitors for Human Factor XIa: Substituted Naphthamidine Series
To be Published
1ZSJ
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH N-(7-CARBAMIMIDOYL-NAPHTHALEN-1-YL)-3-HYDROXY-2-METHYL-BENZAMIDE
Descriptor:Coagulation factor XI, SULFATE ION, BICARBONATE ION, ...
Authors:Guo, Z., Bannister, T., Noll, R., Jin, L., Rynkiewicz, M., Bibbins, F., Magee, S., Gorga, J., Babine, R.E., Strickler, J.E., Meyers, H.V., Abdel-Meguid, S.S.
Deposit date:2005-05-24
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis and Optimization of Potent and Selective Inhibitors for Human Factor XIa: Substituted Naphthamidine Series
To be Published
1ZSK
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH 6-CARBAMIMIDOYL-4-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-NAPHTHALENE-2-CARBOXYLIC ACID METHYL ESTER
Descriptor:Coagulation factor XI, SULFATE ION, BICARBONATE ION, ...
Authors:Guo, Z., Bannister, T., Noll, R., Jin, L., Rynkiewicz, M., Bibbins, F., Magee, S., Gorga, J., Babine, R.E., Strickler, J.E., Meyers, H.V., Abdel-Meguid, S.S.
Deposit date:2005-05-24
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis and Optimization of Potent and Selective Inhibitors for Human Factor XIa: Substituted Naphthamidine Series
To be Published
2IGC
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STRUCTURE OF SPIN LABELED T4 LYSOZYME MUTANT T115R1A
Descriptor:Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Guo, Z., Cascio, D., Hideg, K., Hubbell, W.L.
Deposit date:2006-09-22
Release date:2007-06-12
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein Sci., 16, 2007
2NTG
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STRUCTURE OF SPIN-LABELED T4 LYSOZYME MUTANT T115R7
Descriptor:Lysozyme, S-[(4-bromo-1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, BETA-MERCAPTOETHANOL
Authors:Guo, Z., Cascio, D., Hideg, K., Hubbell, W.L.
Deposit date:2006-11-07
Release date:2007-06-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein Sci., 16, 2007
2NTH
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STRUCTURE OF SPIN-LABELED T4 LYSOZYME MUTANT L118R1
Descriptor:Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Guo, Z., Cascio, D., Hideg, K., Hubbell, W.L.
Deposit date:2006-11-07
Release date:2007-06-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein Sci., 16, 2007
2OU8
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STRUCTURE OF SPIN-LABELED T4 LYSOZYME MUTANT T115R1 AT ROOM TEMPERATURE
Descriptor:Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, BETA-MERCAPTOETHANOL
Authors:Guo, Z., Cascio, D., Hideg, K., Hubbell, W.L.
Deposit date:2007-02-09
Release date:2007-06-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å), EPR
Cite:Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein Sci., 16, 2007
2OU9
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STRUCTURE OF SPIN-LABELED T4 LYSOZYME MUTANT T115R1/R119A
Descriptor:Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Guo, Z., Cascio, D., Hideg, K., Hubbell, W.L.
Deposit date:2007-02-09
Release date:2007-06-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein Sci., 16, 2007
2Q9D
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STRUCTURE OF SPIN-LABELED T4 LYSOZYME MUTANT A41R1
Descriptor:Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, BETA-MERCAPTOETHANOL
Authors:Guo, Z., Cascio, D., Hideg, K., Hubbell, W.L.
Deposit date:2007-06-12
Release date:2007-06-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.4 Å), EPR
Cite:Structural determinants of nitroxide motion in spin-labeled proteins: Solvent-exposed sites in helix B of T4 lysozyme.
Protein Sci., 17, 2008
2Q9E
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STRUCTURE OF SPIN-LABELED T4 LYSOZYME MUTANT S44R1
Descriptor:Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, 2-HYDROXYETHYL DISULFIDE
Authors:Guo, Z., Cascio, D., Hideg, K., Hubbell, W.L.
Deposit date:2007-06-12
Release date:2007-06-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å), EPR
Cite:Structural determinants of nitroxide motion in spin-labeled proteins: Solvent-exposed sites in helix B of T4 lysozyme.
Protein Sci., 17, 2008
3C72
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ENGINEERED RABGGTASE IN COMPLEX WITH A PEPTIDOMIMETIC INHIBITOR
Descriptor:Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ZINC ION, ...
Authors:Guo, Z., Wu, Y.W., Tan, K.T., Bon, R.S., Guiu-Rozas, E., Delon, C., Nguyen, U.T., Wetzel, S., Arndt, S., Goody, R.S., Blankenfeldt, W., Alexandrov, K., Waldmann, H.
Deposit date:2008-02-06
Release date:2008-07-22
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex.
Angew.Chem.Int.Ed.Engl., 47, 2008
3CAE
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STRUCTURE OF NNQQNY AS AN INSERT IN T7 ENDONUCLEASE I
Descriptor:Endonuclease I
Authors:Guo, Z., Eisenberg, D.
Deposit date:2008-02-19
Release date:2008-07-22
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of a fibril-forming sequence, NNQQNY, in the context of a globular fold.
Protein Sci., 17, 2008
3DSS
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CRYSTAL STRUCTURE OF RABGGTASE(DELTA LRR; DELTA IG)
Descriptor:Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ZINC ION, ...
Authors:Guo, Z., Yu, S., Goody, R.S., Alexandrov, K., Blankenfeldt, W.
Deposit date:2008-07-14
Release date:2008-09-09
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
3DST
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CRYSTAL STRUCTURE OF RABGGTASE(DELTA LRR; DELTA IG)IN COMPLEX WITH GERANYLGERANYL PYROPHOSPHATE
Descriptor:Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, GERANYLGERANYL DIPHOSPHATE, ...
Authors:Guo, Z., Yu, S., Goody, R.S., Alexandrov, K., Blankenfeldt, W.
Deposit date:2008-07-14
Release date:2008-09-09
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
3DSU
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CRYSTAL STRUCTURE OF RABGGTASE(DELTA LRR; DELTA IG)IN COMPLEX WITH FARNESYL PYROPHOSPHATE
Descriptor:Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, FARNESYL DIPHOSPHATE, ...
Authors:Guo, Z., Yu, S., Goody, R.S., Alexandrov, K., Blankenfeldt, W.
Deposit date:2008-07-14
Release date:2008-09-09
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
3DSV
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CRYSTAL STRUCTURE OF RABGGTASE(DELTA LRR; DELTA IG)IN COMPLEX WITH MONO-PRENYLATED PEPTIDE SER-CYS-SER-CYS(GG) DERIVATED FROM RAB7
Descriptor:Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ZINC ION, ...
Authors:Guo, Z., Yu, S., Goody, R.S., Alexandrov, K., Blankenfeldt, W.
Deposit date:2008-07-14
Release date:2008-09-09
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
3DSW
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CRYSTAL STRUCTURE OF RABGGTASE(DELTA LRR; DELTA IG)IN COMPLEX WITH MONO-PRENYLATED PEPTIDE SER-CYS(GG)-SER-CYS DERIVATED FROM RAB7
Descriptor:Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ZINC ION, ...
Authors:Guo, Z., Yu, S., Goody, R.S., Alexandrov, K., Blankenfeldt, W.
Deposit date:2008-07-14
Release date:2008-09-09
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
3DSX
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CRYSTAL STRUCTURE OF RABGGTASE(DELTA LRR; DELTA IG)IN COMPLEX WITH DI-PRENYLATED PEPTIDE SER-CYS(GG)-SER-CYS(GG) DERIVATED FROM RAB7
Descriptor:Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ZINC ION, ...
Authors:Guo, Z., Yu, S., Goody, R.S., Alexandrov, K., Blankenfeldt, W.
Deposit date:2008-07-14
Release date:2008-09-09
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
4IFT
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CRYSTAL STRUCTURE OF DOUBLE MUTANT THERMOSTABLE NPPASE FROM GEOBACILLUS STEAROTHERMOPHILUS
Descriptor:Thermostable NPPase
Authors:Guo, Z., Huang, J., Wang, F., Qiu, R., Wang, Y., Ji, C.
Deposit date:2012-12-15
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:Crystal structure of thermostable NPPase from Geobacillus stearothermophilus
To be Published
4KN8
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CRYSTAL STRUCTURE OF BS-TPNPPASE
Descriptor:Thermostable NPPase
Authors:Guo, Z., Wang, F., Huang, J., Gong, W., Ji, C.
Deposit date:2013-05-09
Release date:2014-04-09
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Crystal Structure of Thermostable p-nitrophenylphosphatase from Bacillus Stearothermophilus (Bs-TpNPPase)
PROTEIN PEPT.LETT., 21, 2014
4LHV
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CRYSTAL STRUCTURE OF RAB8 IN ITS INACTIVE GDP-BOUND FORM
Descriptor:Ras-related protein Rab-8A, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Guo, Z., Hou, X.M., Goody, R.S., Itzen, A.
Deposit date:2013-07-01
Release date:2013-10-09
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
4LHW
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CRYSTAL STRUCTURE OF RAB8 IN ITS ACTIVE GPPNHP-BOUND FORM
Descriptor:Ras-related protein Rab-8A, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Guo, Z., Hou, X.M., Goody, R.S., Itzen, A.
Deposit date:2013-07-01
Release date:2013-10-09
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
4LHX
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CRYSTAL STRUCTURE OF NUCLEOTIDE-FREE RAB8:RABIN8
Descriptor:Ras-related protein Rab-8A, Rab-3A-interacting protein, SULFATE ION
Authors:Guo, Z., Hou, X.M., Goody, R.S., Itzen, A.
Deposit date:2013-07-01
Release date:2013-10-09
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
4LHY
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CRYSTAL STRUCTURE OF GDP-BOUND RAB8:RABIN8
Descriptor:Ras-related protein Rab-8A, Rab-3A-interacting protein, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Guo, Z., Hou, X.M., Goody, R.S., Itzen, A.
Deposit date:2013-07-01
Release date:2013-10-09
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013