Author results

4U7T
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CRYSTAL STRUCTURE OF DNMT3A-DNMT3L IN COMPLEX WITH HISTONE H3
分子名称:DNA (cytosine-5)-methyltransferase 3A, DNA (cytosine-5)-methyltransferase 3-like, peptide from Histone H3.3, ...
著者Guo, X., Wang, L., Yin, X., Li, J., Xiao, J., He, S., Wang, J., Xu, Y.
登録日2014-07-31
公開日2014-11-12
最終更新日2015-02-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
Nature, 517, 2015
4ADN
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FUSIDIC ACID RESISTANCE PROTEIN FUSB
分子名称:FAR1, ZINC ION, SODIUM ION, ...
著者Guo, X., Peisker, K., Backbro, K., Chen, Y., Kiran, R.K., Sanyal, S., Selmer, M.
登録日2011-12-31
公開日2012-03-07
最終更新日2012-07-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure and Function of Fusb: An Elongation Factor G-Binding Fusidic Acid Resistance Protein Active in Ribosomal Translocation and Recycling
Open Biol., 2, 2012
4ADO
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FUSIDIC ACID RESISTANCE PROTEIN FUSB
分子名称:FAR1, ZINC ION
著者Guo, X., Peisker, K., Backbro, K., Chen, Y., Kiran, R.K., Sanyal, S., Selmer, M.
登録日2011-12-31
公開日2012-03-07
最終更新日2012-07-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and Function of Fusb: An Elongation Factor G-Binding Fusidic Acid Resistance Protein Active in Ribosomal Translocation and Recycling
Open Biol., 2, 2012
6FLP
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CRYOEM STRUCTURE OF E.COLI RNA POLYMERASE PAUSED ELONGATION COMPLEX WITHOUT RNA HAIRPIN BOUND TO NUSA
分子名称:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Guo, X., Weixlbaumer, A.
登録日2018-01-26
公開日2018-03-07
最終更新日2018-03-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural Basis for NusA Stabilized Transcriptional Pausing.
Mol. Cell, 69, 2018
6FLQ
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CRYOEM STRUCTURE OF E.COLI RNA POLYMERASE PAUSED ELONGATION COMPLEX BOUND TO NUSA
分子名称:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Guo, X., Weixlbaumer, A.
登録日2018-01-26
公開日2018-03-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural Basis for NusA Stabilized Transcriptional Pausing.
Mol. Cell, 69, 2018
5ABT
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S.ENTERICA HISA MUTANT D7N, G102A, V106M, D176A
分子名称:1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENE AMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
著者Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
登録日2015-08-08
公開日2016-09-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The Protein Structures, Functions and Dynamics of Adaptive Evolution
To be Published
5G4W
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S. ENTERICA HISA MUTANT D7N, D10G, DUP13-15 (VVR) WITH SUBSTRATE PROFAR
分子名称:HISA, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, GLYCEROL
著者Guo, X., Soderholm, A., Newton, M., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
登録日2016-05-17
公開日2017-04-19
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4U7P
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CRYSTAL STRUCTURE OF DNMT3A-DNMT3L COMPLEX
分子名称:DNA (cytosine-5)-methyltransferase 3A, DNA (cytosine-5)-methyltransferase 3-like, ZINC ION, ...
著者Wang, L., Guo, X., Li, J., Xiao, J., Yin, X., He, S., Wang, J., Xu, Y.
登録日2014-07-31
公開日2014-11-12
最終更新日2015-02-04
実験手法X-RAY DIFFRACTION (3.821 Å)
主引用文献Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
Nature, 517, 2015
5AB3
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S.ENTERICA HISA MUTANT D7N, D10G, DUP13-15, Q24L, G102A
分子名称:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE, SODIUM ION
著者Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
登録日2015-07-31
公開日2016-09-28
最終更新日2018-06-06
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5AC6
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S.ENTERICA HISA MUTANT D10G, DUP13-15, Q24L, G102A
分子名称:SULFATE ION
著者Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
登録日2015-08-12
公開日2016-09-28
実験手法X-RAY DIFFRACTION (1.993 Å)
主引用文献The Protein Structures, Functions and Dynamics of Adaptive Evolution
To be Published
5G1T
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S. ENTERICA HISA MUTANT DUP13-15, D10G
分子名称:PHOSPHATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
著者Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
登録日2016-03-30
公開日2017-04-19
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G1Y
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S. ENTERICA HISA MUTANT D10G, DUP13-15,V14:2M, Q24L, G102
分子名称:SULFATE ION, GLYCEROL
著者Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
登録日2016-04-01
公開日2017-04-12
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G2I
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S. ENTERICA HISA MUTANT DUP13-15(VVR)
分子名称:PHOSPHATE ION, SODIUM ION
著者Guo, X., Soderholm, A., Newton, M., Nasvall, J., Duarte, F., Andersson, D., Patrick, W., Selmer, M.
登録日2016-04-08
公開日2017-04-19
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G2W
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S. ENTERICA HISA MUTANT D10G, G102A
分子名称:SULFATE ION
著者Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
登録日2016-04-14
公開日2017-04-19
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G5I
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S. ENTERICA HISA MUTANT D10G
分子名称:PHOSPHATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
著者Guo, X., Soderholm, A., Newton, M., Nasvall, J., Andersson, D., Patrick, W., Selmer, M.
登録日2016-05-25
公開日2017-04-19
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5L6U
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S. ENTERICA HISA MUTANT - D10G, DUP13-15, Q24L, G102A
分子名称:HisA, SULFATE ION
著者Guo, X., Soderholm, A., Selmer, M.
登録日2016-05-31
公開日2017-04-19
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5L9F
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S. ENTERICA HISA MUTANT - D10G, G11D, DUP13-15, G44E, G102A
分子名称:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, SODIUM ION, SULFATE ION
著者Guo, X., Soderholm, A., Selmer, M.
登録日2016-06-10
公開日2017-04-19
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5A5W
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CRYSTAL STRUCTURE OF SALMONELLA ENTERICA HISA D7N D176A WITH PROFAR
分子名称:[(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
著者Soderholm, A., Guo, X., Newton, M.S., Evans, G.B., Nasvall, J., Patrick, W.M., Selmer, M.
登録日2015-06-23
公開日2015-09-02
最終更新日2015-10-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Two-Step Ligand Binding in a Beta/Alpha8 Barrel Enzyme -Substrate-Bound Structures Shed New Light on the Catalytic Cycle of Hisa
J.Biol.Chem., 290, 2015
5AHF
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CRYSTAL STRUCTURE OF SALMONELLA ENTERICA HISA D7N WITH PROFAR
分子名称:[(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, GLYCEROL
著者Soderholm, A., Guo, X., Newton, M.S., Evans, G.B., Nasvall, J., Patrick, W.M., Selmer, M.
登録日2015-02-05
公開日2015-09-02
最終更新日2015-10-21
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Two-Step Ligand Binding in a Beta/Alpha8 Barrel Enzyme -Substrate-Bound Structures Shed New Light on the Catalytic Cycle of Hisa
J.Biol.Chem., 290, 2015
5AHI
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CRYSTAL STRUCTURE OF SALMONALLA ENTERICA HISA MUTANT D7N WITH PROFAR
分子名称:1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENE AMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, GLYCEROL, [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate, ...
著者Soderholm, A., Guo, X., Newton, M.S., Evans, G.B., Nasvall, J., Patrick, W.M., Selmer, M.
登録日2015-02-06
公開日2016-03-02
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Structure and Mechanism of Hisa from Salmonella Enterica
To be Published
5GNS
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STRUCTURES OF HUMAN MITOFUSIN 1 PROVIDE INSIGHT INTO MITOCHONDRIAL TETHERING
分子名称:Mitofusin-1, GUANOSINE-5'-TRIPHOSPHATE
著者Qi, Y., Yan, L., Yu, C., Guo, X., Zhou, X., Hu, X., Huang, X., Rao, Z., Lou, Z., Hu, J.
登録日2016-07-24
公開日2016-12-07
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Structures of human Mitofusin 1 provide insight into mitochondrial tethering
To Be Published
4FLA
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CRYSTAL STRUCTURE OF HUMAN RPRD1B, CARBOXY-TERMINAL DOMAIN
分子名称:Regulation of nuclear pre-mRNA domain-containing protein 1B, UNKNOWN ATOM OR ION
著者Ni, Z., Xu, C., Tempel, W., El Bakkouri, M., Loppnau, P., Guo, X., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Greenblatt, J.F., Structural Genomics Consortium (SGC)
登録日2012-06-14
公開日2012-08-22
最終更新日2014-08-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
4FLB
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CID OF HUMAN RPRD2
分子名称:Regulation of nuclear pre-mRNA domain-containing protein 2, SULFATE ION, PRASEODYMIUM ION, ...
著者Ni, Z., Xu, C., Tempel, W., El Bakkouri, M., Loppnau, P., Guo, X., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Greenblatt, J.F., Structural Genomics Consortium (SGC)
登録日2012-06-14
公開日2012-08-15
最終更新日2014-08-20
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
4JXT
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CID OF HUMAN RPRD1A IN COMPLEX WITH A PHOSPHORYLATED PEPTIDE FROM RPB1-CTD
分子名称:Regulation of nuclear pre-mRNA domain-containing protein 1A, DNA-directed RNA polymerase II subunit RPB1, UNKNOWN ATOM OR ION
著者Ni, Z., Xu, C., Tempel, W., El Bakkouri, M., Loppnau, P., Guo, X., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Greenblatt, J.F., Structural Genomics Consortium (SGC)
登録日2013-03-28
公開日2013-11-13
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
4Q96
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CID OF HUMAN RPRD1B IN COMPLEX WITH AN UNMODIFIED CTD PEPTIDE
分子名称:Regulation of nuclear pre-mRNA domain-containing protein 1B, RPB1-CTD, UNKNOWN ATOM OR ION, ...
著者Ni, Z., Xu, C., Tempel, W., El Bakkouri, M., Loppnau, P., Guo, X., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Greenblatt, J.F., Structural Genomics Consortium (SGC)
登録日2014-04-29
公開日2014-06-04
最終更新日2014-08-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014