Author results

6OT1
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CRYO-EM STRUCTURE OF VACCINE-ELICITED ANTIBODY 0PV-B.01 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP AND ANTIBODIES VRC03 AND PGT122
Descriptor:Envelope glycoprotein gp41, BG505 gp120, 0PV-b.01 heavy, ...
Authors:Gorman, J., Kwong, P.D.
Deposit date:2019-05-02
Release date:2019-08-07
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6OSY
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CRYO-EM STRUCTURE OF VACCINE-ELICITED ANTIBODY 0PV-A.01 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP AND ANTIBODIES VRC03 AND PGT122
Descriptor:BG505 gp120, PGT122 Heavy, PGT122 Light, ...
Authors:Gorman, J., Kwong, P.D.
Deposit date:2019-05-02
Release date:2019-07-24
Last modified:2019-08-07
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6NZ7
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CRYSTAL STRUCTURE OF BROADLY NEUTRALIZING INFLUENZA A ANTIBODY 429 B01 IN COMPLEX WITH HEMAGGLUTININ HONG KONG 1968
Descriptor:Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, 429 B01 FAB heavy chain, ...
Authors:Zhou, T., Kwong, P.D.
Deposit date:2019-02-13
Release date:2019-05-08
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine.
Sci Immunol, 4, 2019
6NF2
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CRYO-EM STRUCTURE OF VACCINE-ELICITED ANTIBODY 0PV-C.01 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP AND ANTIBODIES VRC03 AND PGT122
Descriptor:Envelope glycoprotein gp120, Envelope glycoprotein gp41, VRC03 Heavy Chain, ...
Authors:Gorman, J., Kwong, P.D.
Deposit date:2018-12-18
Release date:2019-07-24
Last modified:2019-08-14
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6N16
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VACCINE-ELICITED NHP FP-TARGETING NEUTRALIZING ANTIBODY 0PV-B.01 IN COMPLEX WITH HIV FUSION PEPTIDE (RESIDUE 512-519)
Descriptor:antibody 0PV-b.01 Fab heavy chain, antibody 0PV-b.01 Fab light chain, HIV fusion peptide (512-519)
Authors:Xu, K., Wang, Y., Kwong, P.D.
Deposit date:2018-11-08
Release date:2019-07-31
Last modified:2019-08-07
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQS
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VACCINE-ELICITED NHP FP-TARGETING HIV NEUTRALIZING ANTIBODY A12V163-A.01 IN COMPLEX WITH HIV FUSION PEPTIDE (RESIDUE 512-519)
Descriptor:antibody A12V163-a.01 heavy chain, antibody A12V163-a.01 light chain, HIV fusion peptide residue 512-519
Authors:Xu, K., Wang, Y., Kwong, P.D.
Deposit date:2018-10-10
Release date:2019-07-31
Last modified:2019-08-07
Method:X-RAY DIFFRACTION (2.997 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQR
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VACCINE-ELICITED NHP FP-TARGETING NEUTRALIZING ANTIBODY 0PV-A.01 IN COMPLEX WITH FP (RESIDUE 512-519)
Descriptor:antibody 0PV-A.01 Fab heavy chain, antibody 0PV-A.01 Fab light chain, HIV fusion peptide residue 512-519, ...
Authors:Xu, K., Wang, Y., Kwong, P.D.
Deposit date:2018-10-10
Release date:2019-07-31
Last modified:2019-08-07
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQM
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VACCINE-ELICITED NHP FP-TARGETING NEUTRALIZING ANTIBODY DF1W-A.01 IN COMPLEX WITH HIV FUSION PEPTIDE (RESIDUE 512-519)
Descriptor:antibody Fab heavy chain, antibody Fab light chain, HIV Env fusion peptide residue 512-519
Authors:Xu, K., Wang, Y., Kwong, P.D.
Deposit date:2018-10-10
Release date:2019-07-31
Last modified:2019-08-07
Method:X-RAY DIFFRACTION (3.484 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQE
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VACCINE-ELICITED NHP FP-TARGETING HIV NEUTRALIZING ANTIBODY DFPH-A.15 IN COMPLEX WITH HIV FUSION PEPTIDE (RESIDUE 512-519)
Descriptor:DFPHa.15 antibody Fab light chain, DFPHa.15 antibody Fab heavy chain, HIV fusion peptide
Authors:Xu, K., Wang, Y., Kwong, P.D.
Deposit date:2018-10-09
Release date:2019-07-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.459 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQC
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VACCINE-ELICITED NHP FP-TARGETING NEUTRALIZING ANTIBODY 0PV-C.01 IN COMPLEX WITH FP (RESIDUE 512-519)
Descriptor:0PV-C.01 antibody Fab heavy chain, 0PV-C.01 antibody Fab light chain, HIV fusion peptide residue 512-519
Authors:Xu, K., Wang, Y., Kwong, P.D.
Deposit date:2018-10-09
Release date:2019-07-31
Last modified:2019-08-07
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MOL
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MONOEXTENDED DARPIN M_R12 COMPLEX WITH EPOR
Descriptor:Monoextended DARPin R12 (M_R12), Erythropoietin receptor, GLYCEROL
Authors:Jude, K.M., Mohan, K., Garcia, K.C., Guo, Y.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (3.163 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOK
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DIMERIC DARPIN A_DISTANCE_R7 COMPLEX WITH EPOR
Descriptor:Dimeric DARPin ANR7 (A_distance_r7), Erythropoietin receptor
Authors:Jude, K.M., Mohan, K., Garcia, K.C., Guo, Y.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (5.101 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOJ
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DIMERIC DARPIN A_ANGLE_R5 COMPLEX WITH EPOR
Descriptor:Dimeric DARPin ACR5 (A_angle_R5), Erythropoietin receptor, D(-)-TARTARIC ACID, ...
Authors:Jude, K.M., Mohan, K., Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.431 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOI
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DIMERIC DARPIN C_ANGLE_R5 COMPLEX WITH EPOR
Descriptor:Dimeric DARPing CCR5 (C_angle_R5), Erythropoietin receptor, SULFATE ION, ...
Authors:Jude, K.M., Mohan, K., Garcia, K.C., Guo, Y.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.065 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOH
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DIMERIC DARPIN C_R3 COMPLEX WITH EPOR
Descriptor:Dimeric DARPin E2C (C_R3), Erythropoietin receptor, PHOSPHATE ION, ...
Authors:Jude, K.M., Mohan, K., Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOG
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DIMERIC DARPIN C_R3
Descriptor:DARPin C_R3, 1,2-ETHANEDIOL, TRIETHYLENE GLYCOL
Authors:Jude, K.M., Mohan, K., Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOF
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MONOMERIC DARPIN G2 COMPLEX WITH EPOR
Descriptor:G2 DARPin, Erythropoietin receptor, 1,2-ETHANEDIOL
Authors:Jude, K.M., Mohan, K., Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOE
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MONOMERIC DARPIN E2 COMPLEX WITH EPOR
Descriptor:E2 DARPin, Erythropoietin receptor, PHOSPHATE ION, ...
Authors:Jude, K.M., Mohan, K., Garcia, K.C.
Deposit date:2018-10-04
Release date:2019-06-05
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6J56
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CRYSTAL STRUCTURE OF MYOSIN VI CBD IN COMPLEX WITH TOM1 MBM
Descriptor:Unconventional myosin-VI, Peptide from Target of Myb protein 1
Authors:Hu, S., Pan, L.
Deposit date:2019-01-10
Release date:2019-08-21
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering.
Nat Commun, 10, 2019
6IV7
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THE CRYSTAL STRUCTURE OF A SAM-DEPENDENT ENZYME FROM ASPERGILLUS FLAVUS
Descriptor:methyltransferase lepI, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Zhou, Y.Z., Peng, T., Liao, L.J., Liu, X.K., Zhao, Y.C., Guo, Y., Zeng, Z.X.
Deposit date:2018-12-02
Release date:2019-02-06
Method:X-RAY DIFFRACTION (1.937 Å)
Cite:The crystal structure of A SAM-Dependent enzyme from Aspergillus flavus
To Be Published
6HNQ
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TARP-6RBOP-(CH2)6NH2
Descriptor:Probable ss-1,3-N-acetylglucosaminyltransferase, [(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentyl] [(2~{R},3~{R},4~{S})-2,3,4-tris(oxidanyl)-5-[oxidanyl-[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-phosphonooxy-pentoxy]phosphoryl]oxy-pentyl] hydrogen phosphate, MAGNESIUM ION, ...
Authors:Guo, Y., Stehle, T.
Deposit date:2018-09-17
Release date:2018-10-24
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.
Nature, 563, 2018
6H4M
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TARP-UDP-GLCNAC-3RBOP
Descriptor:Probable ss-1,3-N-acetylglucosaminyltransferase, [(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentyl] [(2~{R},3~{R},4~{S})-2,3,4-tris(oxidanyl)-5-[oxidanyl-[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-phosphonooxy-pentoxy]phosphoryl]oxy-pentyl] hydrogen phosphate, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ...
Authors:Guo, Y., Stehle, T.
Deposit date:2018-07-22
Release date:2018-09-26
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.
Nature, 563, 2018
6H4F
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TARP-3RBOP
Descriptor:Probable ss-1,3-N-acetylglucosaminyltransferase, [(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentyl] [(2~{R},3~{R},4~{S})-2,3,4-tris(oxidanyl)-5-[oxidanyl-[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-phosphonooxy-pentoxy]phosphoryl]oxy-pentyl] hydrogen phosphate, MAGNESIUM ION, ...
Authors:Guo, Y., Stehle, T.
Deposit date:2018-07-21
Release date:2018-09-26
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.
Nature, 563, 2018
6H2N
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TARP-UDP-GLCNAC-MG
Descriptor:Probable ss-1,3-N-acetylglucosaminyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, MAGNESIUM ION, ...
Authors:Guo, Y., Stehle, T.
Deposit date:2018-07-13
Release date:2018-09-26
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.
Nature, 563, 2018
6H21
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TARP-UDP-GLCNAC-MN
Descriptor:Probable ss-1,3-N-acetylglucosaminyltransferase, CHLORIDE ION, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ...
Authors:Guo, Y., Stehle, T.
Deposit date:2018-07-12
Release date:2018-09-26
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity.
Nature, 563, 2018