Author results

4QE7
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OPEN MTHK PORE STRUCTURE SOAKED IN 10 MM BA2+/100 MM NA+
Descriptor:Calcium-gated potassium channel MthK, BARIUM ION
Authors:Guo, R., Zeng, W., Cui, H., Chen, L., Ye, S.
Deposit date:2014-05-15
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ionic interactions of Ba2+ blockades in the MthK K+ channel
J.Gen.Physiol., 144, 2014
4QE9
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OPEN MTHK PORE STRUCTURE SOAKED IN 10 MM BA2+/100 MM K+
Descriptor:Calcium-gated potassium channel MthK, POTASSIUM ION
Authors:Guo, R., Zeng, W., Cui, H., Chen, L., Ye, S.
Deposit date:2014-05-15
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Ionic interactions of Ba2+ blockades in the MthK K+ channel
J.Gen.Physiol., 144, 2014
1NH9
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CRYSTAL STRUCTURE OF A DNA BINDING PROTEIN MJA10B FROM THE HYPERTHERMOPHILE METHANOCOCCUS JANNASCHII
Descriptor:DNA-binding protein Alba
Authors:Wang, G., Bartlam, M., Guo, R., Yang, H., Xue, H., Liu, Y., Huang, L., Rao, Z.
Deposit date:2002-12-19
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeon Methanococcus jannaschii
Protein Sci., 12, 2003
3NBH
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CRYSTAL STRUCTURE OF HUMAN RMI1C-RMI2 COMPLEX
Descriptor:RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2
Authors:Wang, F., Yang, Y., Singh, T.R., Busygina, V., Guo, R., Wan, K., Wang, W., Sung, P., Meetei, A.R., Lei, M.
Deposit date:2010-06-03
Release date:2010-09-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex.
Structure, 18, 2010
3NBI
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CRYSTAL STRUCTURE OF HUMAN RMI1 N-TERMINUS
Descriptor:RecQ-mediated genome instability protein 1
Authors:Wang, F., Yang, Y., Singh, T.R., Busygina, V., Guo, R., Wan, K., Wang, W., Sung, P., Meetei, A.R., Lei, M.
Deposit date:2010-06-03
Release date:2010-09-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex.
Structure, 18, 2010
4PV7
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COCRYSTAL STRUCTURE OF DIPEPTIDYL-PEPTIDASE 4 WITH AN INDOLE SCAFFOLD INHIBITOR
Descriptor:Dipeptidyl peptidase 4 soluble form, 1-[2-(2,4-dichlorophenyl)-1-(methylsulfonyl)-1H-indol-3-yl]methanamine
Authors:Xiao, P., Guo, R., Huang, S., Cui, H., Ye, S., Zhang, Z.
Deposit date:2014-03-15
Release date:2015-03-18
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Discovery of dipeptidyl peptidase IV (DPP4) inhibitors based on a novel indole scaffold
Chin.Chem.Lett., 25, 2014
4RO0
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CRYSTAL STRUCTURE OF MTHK GATING RING IN A LIGAND-FREE FORM
Descriptor:Calcium-gated potassium channel MthK
Authors:Dong, W., Guo, R., Chai, H., Chen, Z., Cui, H., Ren, Z., Li, Y., Ye, S.
Deposit date:2014-10-27
Release date:2015-10-28
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:The principle of cooperative gating in a calcium-gated K+ channel
To be Published
4WJA
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CRYSTAL STRUCTURE OF PAXX
Descriptor:Uncharacterized protein C9orf142
Authors:Xing, M., Yang, M., Huo, W., Feng, F., Wei, L., Ning, S., Yan, Z., Li, W., Wang, Q., Hou, M., Dong, C., Guo, R., Gao, G., Ji, J., Lan, L., Liang, H., Xu, D.
Deposit date:2014-09-29
Release date:2015-03-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway.
Nat Commun, 6, 2015
5GPN
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ARCHITECTURE OF MAMMALIAN RESPIRASOME
Descriptor:Cytochrome b-c1 complex subunit 1, mitochondrial, Cytochrome b-c1 complex subunit 2, ...
Authors:Gu, J., Wu, M., Guo, R., Yang, M.
Deposit date:2016-08-03
Release date:2017-04-05
Last modified:2017-04-12
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:The architecture of the mammalian respirasome.
Nature, 537, 2016
5GUP
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CRYO-EM STRUCTURE OF MAMMALIAN RESPIRATORY SUPERCOMPLEX I1III2IV1
Descriptor:Cytochrome c oxidase subunit 6C, NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, ...
Authors:Gu, J., Wu, M., Guo, R., Yang, M.
Deposit date:2016-08-30
Release date:2017-03-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of Mammalian Respiratory Supercomplex I1III2IV1
Cell, 167, 2016
5D8W
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STRUCTRUE OF A LUCIDUM PROTEIN
Descriptor:Endoglucanase
Authors:Guo, R., Li, Q., Shang, N., Liu, G., Ko, T.P., Chen, C.C., Liu, W.
Deposit date:2015-08-18
Release date:2016-06-29
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Functional and structural analyses of a 1,4-beta-endoglucanase from Ganoderma lucidum.
Enzyme.Microb.Technol., 86, 2016
5D8Z
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STRUCTRUE OF A LUCIDUM PROTEIN
Descriptor:endoglucanase, CELLOBIOSE
Authors:Guo, R., Li, Q., Shang, N., Liu, G., Ko, T.P., Chen, C.C., Liu, W.
Deposit date:2015-08-18
Release date:2016-06-29
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Functional and structural analyses of a 1,4-beta-endoglucanase from Ganoderma lucidum.
Enzyme.Microb.Technol., 86, 2016
5XTB
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CRYO-EM STRUCTURE OF HUMAN RESPIRATORY COMPLEX I MATRIX ARM
Descriptor:NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, ...
Authors:Gu, J., Wu, M., Yang, M.
Deposit date:2017-06-18
Release date:2017-08-30
Last modified:2017-12-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
5XTC
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CRYO-EM STRUCTURE OF HUMAN RESPIRATORY COMPLEX I TRANSMEMBRANE ARM
Descriptor:NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1, ...
Authors:Gu, J., Wu, M., Yang, M.
Deposit date:2017-06-19
Release date:2017-08-30
Last modified:2017-12-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
5XTD
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CRYO-EM STRUCTURE OF HUMAN RESPIRATORY COMPLEX I
Descriptor:NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, ...
Authors:Gu, J., Wu, M., Yang, M.
Deposit date:2017-06-19
Release date:2017-08-30
Last modified:2017-12-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
5XTE
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CRYO-EM STRUCTURE OF HUMAN RESPIRATORY COMPLEX III (CYTOCHROME BC1 COMPLEX)
Descriptor:Cytochrome b-c1 complex subunit 8, Cytochrome b-c1 complex subunit Rieske, mitochondrial, ...
Authors:Gu, J., Wu, M., Yang, M.
Deposit date:2017-06-19
Release date:2017-08-30
Last modified:2017-12-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
5XTH
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CRYO-EM STRUCTURE OF HUMAN RESPIRATORY SUPERCOMPLEX I1III2IV1
Descriptor:NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, ...
Authors:Gu, J., Wu, M., Yang, M.
Deposit date:2017-06-19
Release date:2017-09-13
Last modified:2017-12-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
5XTI
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CRYO-EM ARCHITECTURE OF HUMAN RESPIRATORY CHAIN MEGACOMPLEX-I2III2IV2
Descriptor:NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, ...
Authors:Gu, J., Wu, M., Yang, M.
Deposit date:2017-06-19
Release date:2017-09-13
Last modified:2018-11-28
Method:ELECTRON MICROSCOPY (17.4 Å)
Cite:Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
3WBM
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CRYSTAL STRUCTURE OF PROTEIN-RNA COMPLEX
Descriptor:DNA/RNA-binding protein Alba 1, RNA (25-MER)
Authors:Ding, J., Wang, D.C.
Deposit date:2013-05-20
Release date:2013-12-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural insights into RNA binding by Ssh10b, a member of the highly conserved Sac10b family in Archaea
J.Biol.Chem., 2013
3Q96
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B-RAF KINASE DOMAIN IN COMPLEX WITH A TETRAHYDRONAPHTHALENE INHIBITOR
Descriptor:Serine/threonine-protein kinase B-raf, (2S)-N-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-7-[(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-4-yl)oxy]-1,2,3,4-tetrahydronaphthalene-2-carboxamide
Authors:Sintchak, M.D., Aertgeerts, K., Yano, J.
Deposit date:2011-01-07
Release date:2011-03-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Design and optimization of potent and orally bioavailable tetrahydronaphthalene raf inhibitors.
J.Med.Chem., 54, 2011
3SOU
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STRUCTURE OF UHRF1 PHD FINGER IN COMPLEX WITH HISTONE H3 1-9 PEPTIDE
Descriptor:E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION
Authors:Rajakumara, E., Patel, D.J.
Deposit date:2011-06-30
Release date:2011-08-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8001 Å)
Cite:PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
3SOW
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STRUCTURE OF UHRF1 PHD FINGER IN COMPLEX WITH HISTONE H3K4ME3 1-9 PEPTIDE
Descriptor:E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION
Authors:Rajakumara, E., Patel, D.J.
Deposit date:2011-06-30
Release date:2011-08-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9501 Å)
Cite:PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
3SOX
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STRUCTURE OF UHRF1 PHD FINGER IN THE FREE FORM
Descriptor:E3 ubiquitin-protein ligase UHRF1, ZINC ION
Authors:Rajakumara, E., Patel, D.J.
Deposit date:2011-06-30
Release date:2011-08-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6501 Å)
Cite:PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
5Z62
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STRUCTURE OF HUMAN CYTOCHROME C OXIDASE
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Gu, J., Zong, S., Wu, M., Yang, M.
Deposit date:2018-01-22
Release date:2019-02-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the intact 14-subunit human cytochrome c oxidase.
Cell Res., 28, 2018
5AEL
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T. BRUCEI FARNESYL DIPHOSPHATE SYNTHASE COMPLEXED WITH BISPHOSPHONATE BPH-597
Descriptor:FARNESYL PYROPHOSPHATE SYNTHASE, {2-[3-(hex-1-yn-1-yl)pyridinium-1-yl]ethane-1,1-diyl}bis(phosphonate), MAGNESIUM ION
Authors:Yang, G., Oldfield, E., No, J.H.
Deposit date:2014-12-26
Release date:2015-10-28
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Inhibition of Trypanosoma Brucei Cell Growth by Lipophilic Bisphosphonates: An in Vitro and in Vivo Investigation.
Antimicrob.Agents Chemother., 59, 2015